Drug Resistance, Bacterial
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Subject Areas on Research
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10 x '20 Progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America.
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A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis.
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A 9-Year retrospective review of antibiotic cycling in a surgical intensive care unit.
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A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion.
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A Multicountry Molecular Analysis of Salmonella enterica Serovar Typhi With Reduced Susceptibility to Ciprofloxacin in Sub-Saharan Africa.
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A comparison of neonatal Gram-negative rod and Gram-positive cocci meningitis.
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A crystal structure of a dimer of the antibiotic ramoplanin illustrates membrane positioning and a potential Lipid II docking interface.
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A novel diagnostic approach may reduce inappropriate antibiotic use for acute respiratory infections.
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A prospective study of Escherichia coli bloodstream infection among adolescents and adults in northern Tanzania.
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Adapting environmental surveillance for polio to the need to track antimicrobial resistance.
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Advances in basic and translational tuberculosis research: Proceedings of the first meeting of RePORT international.
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Advances in the management of pulmonary disease due to Mycobacterium abscessus complex.
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Advancing Diagnostics to Address Antibacterial Resistance: The Diagnostics and Devices Committee of the Antibacterial Resistance Leadership Group.
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Adverse consequences of neonatal antibiotic exposure.
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Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics.
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An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli.
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Analysis of the potential for point-of-care test to enable individualised treatment of infections caused by antimicrobial-resistant and susceptible strains of Neisseria gonorrhoeae
: a modelling study.
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Analysis of two- and three-year trends in antimicrobial resistance in intensive care units using unit-specific antibiograms.
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Antibacterial Resistance Leadership Group 2.0: Back to Business.
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Antibacterial resistance leadership group: open for business.
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Antibiotic Susceptibility of Escherichia coli Among Infants Admitted to Neonatal Intensive Care Units Across the US From 2009 to 2017.
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Antibiotic development - economic, regulatory and societal challenges.
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Antibiotic stewardship: reassessment of guidelines for management of neonatal sepsis.
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Antibiotic use and misuse in the neonatal intensive care unit.
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Antibiotic-resistant bacteria on personal devices in hospital intensive care units: Molecular approaches to quantifying and describing changes in the bacterial community of personal mobile devices.
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Antibiotics as a selective driver for conjugation dynamics.
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Antimicrobial resistance and genetic background of non-typhoidal Salmonella enterica strains isolated from human infections in São Paulo, Brazil (2000-2019).
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Antimicrobial resistance genes are enriched in aerosols near impacted urban surface waters in La Paz, Bolivia.
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Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei.
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Antimicrobial stewardship and infection prevention-leveraging the synergy: A position paper update.
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Antimicrobial stewardship programs in community hospitals: the evidence base and case studies.
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Antimicrobial stewardship programs: how to start and steer a successful program.
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Antimicrobial stewardship: a matter of process or outcome?
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Antimicrobial-Resistant Shigella spp. in San Diego, California, USA, 2017-2020.
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Applying ecological resistance and resilience to dissect bacterial antibiotic responses.
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Bacteremia in lung transplant recipients in the current era.
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Bacterial conversion of folinic acid is required for antifolate resistance.
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Bacterial infections in Lilongwe, Malawi: aetiology and antibiotic resistance.
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Bacteriologic features of surgical site infections following breast surgery.
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Barriers to implementing antimicrobial stewardship programs in three low- and middle-income country tertiary care settings: findings from a multi-site qualitative study.
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Bloodstream infections in community hospitals in the 21st century: a multicenter cohort study.
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Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients.
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Carbapenems for surgical prophylaxis?
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Challenges in the Diagnosis and Management of Bacterial Lung Infections in Solid Organ Recipients: A Narrative Review.
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Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae.
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Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus.
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Clinical response and outcome of infection with Salmonella enterica serotype Typhi with decreased susceptibility to fluoroquinolones: a United States foodnet multicenter retrospective cohort study.
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Collective antibiotic tolerance: mechanisms, dynamics and intervention.
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Colonization With Levofloxacin-resistant Extended-spectrum β-Lactamase-producing Enterobacteriaceae and Risk of Bacteremia in Hematopoietic Stem Cell Transplant Recipients.
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Combating antimicrobial resistance: policy recommendations to save lives.
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Community-acquired MRSA infections in North Carolina children: prevalence, antibiotic sensitivities, and risk factors.
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Comparison of microscan broth microdilution, synergy quad plate agar dilution, and disk diffusion screening methods for detection of high-level aminoglycoside resistance in enterococcus species.
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Confronting antimicrobial resistance together.
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Controlling antimicrobial resistance in the hospital.
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Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria.
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Current best practices and guidelines. Assessment and management of complications in infective endocarditis.
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Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones.
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DNA damage responses in prokaryotes: regulating gene expression, modulating growth patterns, and manipulating replication forks.
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Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content.
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Daptomycin-resistant Enterococcus faecalis diverts the antibiotic molecule from the division septum and remodels cell membrane phospholipids.
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Daptomycin: a rapidly bactericidal lipopeptide for the treatment of Gram-positive infections.
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Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR).
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Detection of inducible clindamycin resistance in staphylococci by broth microdilution using erythromycin-clindamycin combination wells.
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Direct-from-blood RNA sequencing identifies the cause of post-bronchoscopy fever.
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Dissecting the effects of antibiotics on horizontal gene transfer: Analysis suggests a critical role of selection dynamics.
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Distribution of serotypes and antibiotic resistance of invasive Pseudomonas aeruginosa in a multi-country collection.
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Effect of trimethoprim-sulfamethoxazole prophylaxis on antimicrobial resistance of fecal Escherichia coli in HIV-infected patients in Tanzania.
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Effects of Sexual Network Connectivity and Antimicrobial Drug Use on Antimicrobial Resistance in Neisseria gonorrhoeae.
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Efficacy of anti-pseudomonal antibiotics: need to reconsider the empirical use of cefepime.
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Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular Pathogen.
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Emerging moxifloxacin resistance in Pseudomonas aeruginosa keratitis isolates in South India.
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Emerging options for treatment of invasive, multidrug-resistant Staphylococcus aureus infections.
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Enterococcal endocarditis in the beginning of the 21st century: analysis from the International Collaboration on Endocarditis-Prospective Cohort Study.
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Environmental and genetic determinants of plasmid mobility in pathogenic Escherichia coli.
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Envisioning Future Urinary Tract Infection Diagnostics.
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Epidemiology and risk factors for endemic typhoid fever in Uzbekistan.
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Epidemiology of highly endemic multiply antibiotic-resistant shigellosis in children in the Peruvian Amazon.
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Exogenous reinfection of tuberculosis in a low-burden area.
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Expert Consensus on Metrics to Assess the Impact of Patient-Level Antimicrobial Stewardship Interventions in Acute-Care Settings.
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Extensively drug-resistant tuberculosis: are we learning from history or repeating it?
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Facilitation of robust growth of Prochlorococcus colonies and dilute liquid cultures by "helper" heterotrophic bacteria.
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From the Centers for Disease Control and Prevention. Disseminated infection with Simiae-avium group mycobacteria in persons with AIDS--Thailand and Malawi, 1997.
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Generation of ramoplanin-resistant Staphylococcus aureus.
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Gram-Negative Bacterial Infections: Research Priorities, Accomplishments, and Future Directions of the Antibacterial Resistance Leadership Group.
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Gram-Positive Bacterial Infections: Research Priorities, Accomplishments, and Future Directions of the Antibacterial Resistance Leadership Group.
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Gut Colonization Preceding Mucosal Barrier Injury Bloodstream Infection in Pediatric Hematopoietic Stem Cell Transplantation Recipients.
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Harmonisation in study design and outcomes in paediatric antibiotic clinical trials: a systematic review.
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History of antibiotics: from fluoroquinolones to daptomycin (Part 2).
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Iclaprim: a differentiated option for the treatment of skin and skin structure infections.
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Implementation of antibiotic rotation protocol improves antibiotic susceptibility profile in a surgical intensive care unit.
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In vitro activity of amikacin against isolates of Mycobacterium avium complex with proposed MIC breakpoints and finding of a 16S rRNA gene mutation in treated isolates.
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In vitro activity of telithromycin against macrolide-susceptible and macrolide-resistant pharyngeal isolates of group A streptococci in the United States.
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Incorporation of secretory immunoglobulin A into biofilms can decrease their resistance to ciprofloxacin.
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Infected bilomas in liver transplant recipients, incidence, risk factors and implications for prevention.
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Infective endocarditis caused by daptomycin-resistant Enterococcus faecalis: a case report.
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Intermittent tuberculosis treatment for patients with isoniazid intolerance or drug resistance.
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International prevalence and risk factors evaluation for drug-resistant Streptococcus pneumoniae pneumonia.
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Intestinal alkaline phosphatase promotes gut bacterial growth by reducing the concentration of luminal nucleotide triphosphates.
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Invasive gram-positive bacterial infection in cancer patients.
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Invasive non-Typhi Salmonella disease in Africa.
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Isomeric N-alkylpyridylporphyrins and their Zn(II) complexes: inactive as SOD mimics but powerful photosensitizers.
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Lessons learned from the anaerobe survey: historical perspective and review of the most recent data (2005-2007).
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Levofloxacin-resistant-Streptococcus mitis endophthalmitis: a unique presentation of bacterial endocarditis.
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Low prevalence of Pneumocystis pneumonia (PCP) but high prevalence of pneumocystis dihydropteroate synthase (dhps) gene mutations in HIV-infected persons in Uganda.
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MASTERMIND: Bringing Microbial Diagnostics to the Clinic.
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Measuring the effect of inappropriate initial antibiotic therapy on outcomes of patients with Gram-negative sepsis: An imprecise science.
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Methicillin-resistant Staphylococcus aureus: an evolving pathogen.
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Microbial inactivation of Pseudomonas putida and Pichia pastoris using gene silencing.
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Microbiology of ventilator-associated pneumonia compared with that of hospital-acquired pneumonia.
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Molecular Diagnostics for Mycobacterium tuberculosis Infection.
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Molecular identification of streptomycin monoresistant Mycobacterium tuberculosis related to multidrug-resistant W strain.
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Multicenter study to determine disk diffusion and broth microdilution criteria for prediction of high- and low-level mupirocin resistance in Staphylococcus aureus.
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Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA.
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Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3-β4 loop to favor a low-affinity drug-binding state.
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Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity.
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Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease.
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National survey on the susceptibility of Bacteroides Fragilis Group: report and analysis of trends for 1997-2000.
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National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004.
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Neonatal Escherichia coli Bloodstream Infections: Clinical Outcomes and Impact of Initial Antibiotic Therapy.
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New Molecular Diagnostic Approaches to Bacterial Infections and Antibacterial Resistance.
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Office-Based Strategies to Combat Antimicrobial Resistance.
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Open Waste Canals as Potential Sources of Antimicrobial Resistance Genes in Aerosols in Urban Kanpur, India.
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Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions.
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Pathogen flow: what we need to know.
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Patient and physician attitudes regarding risk and benefit in streamlined development programmes for antibacterial drugs: a qualitative analysis.
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Pediatric-specific antimicrobial susceptibility data and empiric antibiotic selection.
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Persistence and reversal of plasmid-mediated antibiotic resistance.
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Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance.
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Population-based surveillance of typhoid fever in Egypt.
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Predictors of Infectious Complications after Targeted Prophylaxis for Prostate Needle Biopsy.
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Predictors of fluoroquinolone-resistant bacteria in the rectal vault of men undergoing prostate biopsy.
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Predictors of mortality in patients with bloodstream infection due to ceftazidime-resistant Klebsiella pneumoniae.
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Rapid molecular detection of tuberculosis and rifampin resistance.
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Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection.
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Reevaluating fluoroquinolone breakpoints for Salmonella enterica serotype Typhi and for non-Typhi salmonellae.
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Reevaluation of Clinical and Laboratory Standards Institute disk diffusion breakpoints for tetracyclines for testing Enterobacteriaceae.
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Reply to Phillips, Morris, and Walker.
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Research needs in antibiotic stewardship.
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Resistance diagnosis and the changing economics of antibiotic discovery.
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Resistance diagnosis and the changing epidemiology of antibiotic resistance.
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Sequential emergence of antibiotic resistance in enterococcal bloodstream isolates over 25 years.
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Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition.
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Staphylococcus aureus bacteremia and endocarditis.
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Streptococcus mitis and S. oralis Lack a Requirement for CdsA, the Enzyme Required for Synthesis of Major Membrane Phospholipids in Bacteria.
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Structure, inhibition, and regulation of essential lipid A enzymes.
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Surveillance of carbapenem-resistant Klebsiella pneumoniae: tracking molecular epidemiology and outcomes through a regional network.
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Surveillance of iclaprim activity: in vitro susceptibility of Gram-positive skin infection pathogens collected from 2015 to 2016 from North America and Europe.
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Survival of lung transplant patients with cystic fibrosis harboring panresistant bacteria other than Burkholderia cepacia, compared with patients harboring sensitive bacteria.
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Telavancin.
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Telavancin: a new lipoglycopeptide for gram-positive infections.
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The Antibacterial Resistance Leadership Group: Progress Report and Work in Progress.
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The Effect of Catheterization on Susceptibility of Uropathogens After Pelvic Reconstructive Surgery.
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The Role of Stewardship in Addressing Antibacterial Resistance: Stewardship and Infection Control Committee of the Antibacterial Resistance Leadership Group.
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The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions.
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The potential for community exposures to pathogens from an urban dairy.
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The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
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Tigecycline disk diffusion breakpoints of Acinetobacter spp.: a clinical point of view.
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Tigecycline therapy for carbapenem-resistant Klebsiella pneumoniae (CRKP) bacteriuria leads to tigecycline resistance.
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Transcription-associated mutation of lasR in Pseudomonas aeruginosa.
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Transforming Concepts Into Clinical Trials and Creating a Multisite Network: The Leadership and Operations Center of the Antibacterial Resistance Leadership Group.
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Urgent, Comprehensive Federal Action Needed To Stem Mortality and Medicare Costs Associated With Antimicrobial Resistance.
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Vital signs: improving antibiotic use among hospitalized patients.
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When two for the price of one isn't a bargain: estimating prevalence and microbiology of bacterial co-infections in patients with COVID-19.
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White paper: recommendations on the conduct of superiority and organism-specific clinical trials of antibacterial agents for the treatment of infections caused by drug-resistant bacterial pathogens.
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Whole-genome sequencing of Staphylococcus epidermidis bloodstream isolates from a prospective clinical trial reveals that complicated bacteraemia is caused by a limited number of closely related sequence types.
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Keywords of People
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Moehring, Rebekah,
Associate Professor of Medicine,
Medicine, Infectious Diseases
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Pasquale, Dana Kristine,
Assistant Professor in Population Health Sciences,
Population Health Sciences
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Sullivan, Daniel Carl,
Professor Emeritus of Radiology,
Radiology