Drug Resistance, Multiple, Bacterial
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Subject Areas on Research
- A community-based study of the incidence of trimethoprim-sulfamethoxazole-preventable infections in Malawian adults living with HIV.
- Central nervous system infection and cutaneous lymphadenitis due to Mycobacterium kansasii in an immunocompetent patient.
- Control of simultaneous outbreaks of carbapenemase-producing enterobacteriaceae and extensively drug-resistant Acinetobacter baumannii infection in an intensive care unit using interventions promoted in the Centers for Disease Control and Prevention 2012 carbapenemase-resistant Enterobacteriaceae Toolkit.
- Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC.
- Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR.
- Effective cohorting and "superisolation" in a single intensive care unit in response to an outbreak of diverse multi-drug-resistant organisms.
- Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection).
- Efficacy of colistin-impregnated beads to prevent multidrug-resistant A. baumannii implant-associated osteomyelitis.
- Emergence of fluoroquinolone resistance among Bacteroides species.
- Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study.
- Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene.
- Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains.
- Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance.
- High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors.
- HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
- Immunotherapy for refractory pulmonary infection after adult cardiac surgery: immune dysregulation syndrome.
- Implementation of strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in U.S. hospitals.
- Important cellular targets for antimicrobial photodynamic therapy.
- Increased Costs Associated with Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Bacteria Are Due Primarily to Patients with Hospital-Acquired Infections.
- Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
- Multicenter studies of tigecycline disk diffusion susceptibility results for Acinetobacter spp.
- Multidrug-resistant chronic osteomyelitis complicating war injury in Iraqi civilians.
- Oritavancin for acute bacterial skin and skin structure infections.
- Outcomes of transplantation using organs from a donor infected with Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae.
- Phosphate-containing polyethylene glycol polymers prevent lethal sepsis by multidrug-resistant pathogens.
- Reduced Chlorhexidine and Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium after Serial Chlorhexidine Exposure.
- Repairing the broken market for antibiotic innovation.
- Residence in Skilled Nursing Facilities Is Associated with Tigecycline Nonsusceptibility in Carbapenem-Resistant Klebsiella pneumoniae.
- Reversal of P-glycoprotein expressed in Escherichia coli leaky mutant by ascorbic acid.
- Role of newer and re-emerging older agents in the treatment of infections caused by carbapenem-resistant Enterobacteriaceae.
- Role of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance.
- Safety, tolerability, and efficacy of GSK1322322 in the treatment of acute bacterial skin and skin structure infections.
- Selection of strains for quality assessment of the disk induction method for detection of inducible clindamycin resistance in Staphylococci: a CLSI collaborative study.
- Shedding light on new methods to improve hospital cleanliness: the use of ultraviolet monitors as surrogate markers for bacterial contamination.
- Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
- Structural mechanisms of QacR induction and multidrug recognition.
- The complexities of Xpert® MTB/RIF interpretation.
- The effect of pulmonary surfactant on the in vitro activity of Iclaprim against common respiratory bacterial pathogens.
- The evolution of drug resistance in Mycobacterium tuberculosis: from a mono-rifampin-resistant cluster into increasingly multidrug-resistant variants in an HIV-seropositive population.
- The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus.
- The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa.
- Uncovering scaling laws to infer multidrug response of resistant microbes and cancer cells.
- Utility of a clinical risk factor scoring model in predicting infection with extended-spectrum β-lactamase-producing enterobacteriaceae on hospital admission.
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Keywords of People
- Guan, Ziqiang, Research Professor in Biochemistry, Biochemistry