Molecular Diagnostic Techniques
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Subject Areas on Research
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A lyophilized colorimetric RT-LAMP test kit for rapid, low-cost, at-home molecular testing of SARS-CoV-2 and other pathogens.
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A quality control program within a clinical trial Consortium for PCR protocols to detect Plasmodium species.
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A rationale for conducting parallel mechanistic studies in clinical trials of pharmacotherapy.
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Advancing Diagnostics to Address Antibacterial Resistance: The Diagnostics and Devices Committee of the Antibacterial Resistance Leadership Group.
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Advancing the boundaries of molecular imaging.
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Better tests, better care: improved diagnostics for infectious diseases.
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Biomarkers for amyotrophic lateral sclerosis.
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Block-diagonal discriminant analysis and its bias-corrected rules.
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Cancer characterization and feature set extraction by discriminative margin clustering.
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Clinical application of exome sequencing in undiagnosed genetic conditions.
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Clinical genomic testing: getting it right.
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Clinical utility of quantitative imaging.
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Comparative effectiveness research and demonstrating clinical utility for molecular diagnostic tests.
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Comparison of commercial influenza A virus assays in detecting avian influenza H7N9 among poultry cloacal swabs, China.
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Cost-Effectiveness of High-Risk Human Papillomavirus Testing With Messenger RNA Versus DNA Under United States Guidelines for Cervical Cancer Screening.
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Detection of occult N2 disease with molecular techniques.
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Detection of pathogen-specific antibodies by loop-mediated isothermal amplification.
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Determination of human platelet antigen typing by molecular methods: Importance in diagnosis and early treatment of neonatal alloimmune thrombocytopenia.
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Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis.
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Development of a TaqMan Array Card for Acute-Febrile-Illness Outbreak Investigation and Surveillance of Emerging Pathogens, Including Ebola Virus.
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Developments in Molecular Testing and Biosimilars.
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Diagnostic performance of two highly multiplexed respiratory virus assays in a pediatric cohort.
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Direct Detection of Unamplified Pathogen RNA in Blood Lysate using an Integrated Lab-in-a-Stick Device and Ultrabright SERS Nanorattles.
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Discussing Health Care Expenses in the Oncology Clinic: Analysis of Cost Conversations in Outpatient Encounters.
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Do Ultrasound Patterns and Clinical Parameters Inform the Probability of Thyroid Cancer Predicted by Molecular Testing in Nodules with Indeterminate Cytology?
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Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer.
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Genes with bimodal expression are robust diagnostic targets that define distinct subtypes of epithelial ovarian cancer with different overall survival.
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Getting small is suddenly very big: review of the proceedings of the third annual meeting of the Society for Molecular Imaging.
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Host-Based Peripheral Blood Gene Expression Analysis for Diagnosis of Infectious Diseases.
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Immune profiling: molecular monitoring in renal transplantation.
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Impact of molecular testing on reported Clostridoides difficile infection rates.
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Impact of multiple policy interventions on the screening and diagnosis of drug-resistant tuberculosis patients: a cascade analysis on six prefectures in China.
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Impact of strain type on detection of toxigenic Clostridium difficile: comparison of molecular diagnostic and enzyme immunoassay approaches.
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Integration of molecular diagnostics with therapeutics: implications for drug discovery and patient care.
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Intraoperative pathologic examination in the era of molecular testing for differentiated thyroid cancer.
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Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases.
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MOLECULAR PROGNOSTICS FOR UVEAL MELANOMA.
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Methods and challenges in quantitative imaging biomarker development.
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Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens.
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Molecular malaria epidemiology: mapping and burden estimates for the Democratic Republic of the Congo, 2007.
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Multicenter evaluation of the LightCycler methicillin-resistant Staphylococcus aureus (MRSA) advanced test as a rapid method for detection of MRSA in nasal surveillance swabs.
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Multicenter, prospective clinical evaluation of respiratory samples from subjects at risk for Pneumocystis jirovecii infection by use of a commercial real-time PCR assay.
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Multiplex 5' nuclease quantitative real-time PCR for clinical diagnosis of malaria and species-level identification and epidemiologic evaluation of malaria-causing parasites, including Plasmodium knowlesi.
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NCCN Clinical Practice Guidelines Occult primary.
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New Molecular Diagnostic Approaches to Bacterial Infections and Antibacterial Resistance.
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Non-small cell lung cancer.
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Performance of diagnostic tests to detect respiratory viruses in older adults.
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Personalized targeted therapy for esophageal squamous cell carcinoma.
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Physical Crossmatching vs Virtual Crossmatching: The end of an era? or Why give up a good thing?
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Prevalence and density-related concordance of three diagnostic tests for malaria in a region of Tanzania with hypoendemic malaria.
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Prevalence, incidence, and natural history of HPV infection in adult women ages 24 to 45 participating in a vaccine trial.
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Quantifying SARS-CoV-2 viral load: current status and future prospects.
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Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam Against Pseudomonas aeruginosa: PRIMERS IV.
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Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II.
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Robust detection of EGFR copy number changes and EGFR variant III: technical aspects and relevance for glioma diagnostics.
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Seeing into cells. The promise of in vivo molecular imaging in oncology.
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Serum biomarker panels for the detection of pancreatic cancer.
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Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay.
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Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists.
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Study protocol for a cluster-randomized trial to compare human papillomavirus based cervical cancer screening in community-health campaigns versus health facilities in western Kenya.
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Systematic review of the performance of HIV viral load technologies on plasma samples.
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Target Product Profile for a Diagnostic Assay to Differentiate between Bacterial and Non-Bacterial Infections and Reduce Antimicrobial Overuse in Resource-Limited Settings: An Expert Consensus.
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Targeted Re-Sequencing Emulsion PCR Panel for Myopathies: Results in 94 Cases.
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The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer.
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The NEXT-1 (Next generation pErsonalized tX with mulTi-omics and preclinical model) trial: prospective molecular screening trial of metastatic solid cancer patients, a feasibility analysis.
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The complexities of Xpert® MTB/RIF interpretation.
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The current epidemiology and clinical decisions surrounding acute respiratory infections.
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The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation.
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The host response as a tool for infectious disease diagnosis and management.
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The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice.
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The value of fluorescence in situ hybridization and polymerase chain reaction in the diagnosis of B-cell non-Hodgkin lymphoma by fine-needle aspiration.
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Translating genomic biomarkers into clinically useful diagnostics.
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Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.
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Keywords of People
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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Sullivan, Daniel Carl,
Professor Emeritus of Radiology,
Radiology
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Tsalik, Ephraim,
Adjunct Associate Professor in the Department of Medicine,
Medicine, Infectious Diseases