Hyphae

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  Subject Areas on Research

  • A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans. 
  • Antifungal drug resistance evoked via RNAi-dependent epimutations. 
  • Aspergillus fumigatus calcipressin CbpA is involved in hyphal growth and calcium homeostasis. 
  • Axl2 integrates polarity establishment, maintenance, and environmental stress response in the filamentous fungus Ashbya gossypii. 
  • Biomass and compositional responses of ectomycorrhizal fungal hyphae to elevated CO2 and nitrogen fertilization. 
  • CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. 
  • CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival. 
  • Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis. 
  • Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis. 
  • Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae. 
  • Calcineurin localizes to the hyphal septum in Aspergillus fumigatus: implications for septum formation and conidiophore development. 
  • Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides. 
  • Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. 
  • Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus. 
  • Calcineurin-binding protein Cbp1 directs the specificity of calcineurin-dependent hyphal elongation during mating in Cryptococcus neoformans. 
  • Campafungins: Inhibitors of Candida albicans and Cryptococcus neoformans Hyphal Growth. 
  • Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha. 
  • Cerebral phaeohyphomycosis mimics high-grade astrocytoma. 
  • Chlamydospore formation during hyphal growth in Cryptococcus neoformans. 
  • Control of filamentous fungal cell shape by septins and formins. 
  • Divergent Roles for cAMP-PKA Signaling in the Regulation of Filamentous Growth in Saccharomyces cerevisiae and Saccharomyces bayanus . 
  • Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen. 
  • Fungal morphogenesis. 
  • Genetic circuits that govern bisexual and unisexual reproduction in Cryptococcus neoformans. 
  • Gpr1, a putative G-protein-coupled receptor, regulates morphogenesis and hypha formation in the pathogenic fungus Candida albicans. 
  • Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. 
  • Identification of cell cycle-regulated, putative hyphal genes in Candida albicans. 
  • Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis. 
  • Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus. 
  • Maximal polar growth potential depends on the polarisome component AgSpa2 in the filamentous fungus Ashbya gossypii. 
  • Nuclear anarchy: asynchronous mitosis in multinucleated fungal hyphae. 
  • PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex. 
  • Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition. 
  • Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans. 
  • Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus. 
  • Photo Quiz: A 9-Year-Old Girl with Eye Swelling and Drainage. 
  • Profiling a killer, the development of Cryptococcus neoformans. 
  • Pseudohyphal growth of Cryptococcus neoformans is a reversible dimorphic transition in response to ammonium that requires Amt1 and Amt2 ammonium permeases. 
  • Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans. 
  • Sexual reproduction of human fungal pathogens. 
  • Spores as infectious propagules of Cryptococcus neoformans. 
  • Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design. 
  • Surfactant protein D binding to Aspergillus fumigatus hyphae is calcineurin-sensitive. 
  • The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans. 
  • The RGS protein Crg2 regulates both pheromone and cAMP signalling in Cryptococcus neoformans. 
  • The TOR signal transduction cascade controls cellular differentiation in response to nutrients. 
  • The heterotrimeric G-protein beta subunit Gpb1 controls hyphal growth under low oxygen conditions through the protein kinase A pathway and is essential for virulence in the fungus Mucor circinelloides. 
  • The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. 
  • The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth. 
  • Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators. 
  • Trimorphic stepping stones pave the way to fungal virulence. 
  • Two CDC42 paralogues modulate Cryptococcus neoformans thermotolerance and morphogenesis under host physiological conditions. 
  • Unisexual reproduction enhances fungal competitiveness by promoting habitat exploration via hyphal growth and sporulation. 
  • Unisexual reproduction of Cryptococcus gattii. 
  • Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans. 
  • Unisexual versus bisexual mating in Cryptococcus neoformans: Consequences and biological impacts. 
  • Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation.