WT1 Proteins

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  Subject Areas on Research

  • A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. 
  • COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. 
  • Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • Colocalization of WT1 and cell proliferation reveals conserved mechanisms in temperature-dependent sex determination. 
  • Dysregulation of WTI (-KTS) is Associated with the Kidney-Specific Effects of the LMX1B R246Q Mutation. 
  • Estrogen represses SOX9 during sex determination in the red-eared slider turtle Trachemys scripta. 
  • Expression and mutation analysis of the Wilms' tumor 1 gene in human neural tumors. 
  • HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. 
  • HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy. 
  • Immunotherapeutic targeting of Wilms' tumor protein. 
  • Induction of Wilms' tumor protein (WT1)-specific antitumor immunity using a truncated WT1-expressing adenovirus vaccine. 
  • Mutational analysis of NPHS2 and WT1 in frequently relapsing and steroid-dependent nephrotic syndrome. 
  • Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS). 
  • Nephrotic syndrome in the first year of life: two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2). 
  • Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression. 
  • Restricted expression of WT1 messenger ribonucleic acid in immature ovarian follicles: uniformity in mammalian and avian species and maintenance during reproductive senescence. 
  • WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells. 
  • WT1 and DAX-1 regulate SF-1-mediated human P450arom gene expression in gonadal cells. 
  • WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis. 
  • WT1 vaccination in acute myeloid leukemia: new methods of implementing adoptive immunotherapy.