Tumor Suppressor Protein p14ARF
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Subject Areas on Research
- A spatially and temporally restricted mouse model of soft tissue sarcoma.
- Aberrant promoter methylation of multiple genes in non-small cell lung cancers.
- An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction.
- Correspondence re: Geradts J, Wilentz RE, Roberts H. Immunohistochemical detection of the alternate ink4a-encoded tumor suppressor protein p14(arf) in archival human cancers and cell lines using commercial antibodies: correlation with p16(ink4a) expression. Mod pathol 2001;14:1162-68.
- Genetic variants in p53-related genes confer susceptibility to second primary malignancy in patients with index squamous cell carcinoma of head and neck.
- Genetic variation in MDM2 and p14ARF and susceptibility to salivary gland carcinoma.
- Immunohistochemical [corrected] detection of the alternate INK4a-encoded tumor suppressor protein p14(ARF) in archival human cancers and cell lines using commercial antibodies: correlation with p16(INK4a) expression.
- Potentially functional variants of p14ARF are associated with HPV-positive oropharyngeal cancer patients and survival after definitive chemoradiotherapy.
- Replicative senescence revisited.
- Significance of MDM2 and P14 ARF polymorphisms in susceptibility to differentiated thyroid carcinoma.
- p14ARF genetic polymorphisms and susceptibility to second primary malignancy in patients with index squamous cell carcinoma of the head and neck.
- p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.