Subject Areas on Research
- Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling.
- Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.
- K63 polyubiquitination is a new modulator of the oxidative stress response.
- Mechanical unfolding of ubiquitin molecules.
- Polyubiquitin Chains Linked by Lysine Residue 48 (K48) Selectively Target Oxidized Proteins In Vivo.
- The mechanical stability of ubiquitin is linkage dependent.