Amino Acid Transport System X-AG
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Subject Areas on Research
- Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity.
- Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.
- Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.
- NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro.
- Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism.
- Photoreceptor synapses degenerate early in experimental choroidal neovascularization.
- Role of the GLT-1 subtype of glutamate transporter in glutamate homeostasis: the GLT-1-preferring inhibitor WAY-855 produces marginal neurotoxicity in the rat hippocampus.
- Synaptic activation of presynaptic glutamate transporter currents in nerve terminals.
- Temporal changes in glutamate, glutamate transporters, basilar arteries wall thickness, and neuronal variability in an experimental rat model of subarachnoid hemorrhage.
- The development of excitatory synapses in cultured spinal neurons.
- Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants.