Enterovirus B, Human

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  Subject Areas on Research

  • ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry. 
  • An In Vivo Model of Echovirus-Induced Meningitis Defines the Differential Roles of Type I and Type III Interferon Signaling in Central Nervous System Infection. 
  • Apolipoprotein J/clusterin induction in myocarditis: A localized response gene to myocardial injury. 
  • BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery. 
  • BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication. 
  • Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells. 
  • Comparative RNAi screening reveals host factors involved in enterovirus infection of polarized endothelial monolayers. 
  • Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. 
  • Dynamin- and lipid raft-dependent entry of decay-accelerating factor (DAF)-binding and non-DAF-binding coxsackieviruses into nonpolarized cells. 
  • Enterovirus Replication and Dissemination Are Differentially Controlled by Type I and III Interferons in the Gastrointestinal Tract. 
  • Enterovirus causes rapidly progressive dementia in a 28-year-old immunosuppressed woman. 
  • Enteroviruses in the early 21st century: new manifestations and challenges. 
  • Focal adhesion kinase mediates the interferon-gamma-inducible GTPase-induced phosphatidylinositol 3-kinase/Akt survival pathway and further initiates a positive feedback loop of NF-kappaB activation. 
  • Genetic adaptation to untranslated region-mediated enterovirus growth deficits by mutations in the nonstructural proteins 3AB and 3CD. 
  • Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice. 
  • Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells. 
  • Lipid raft- and SRC family kinase-dependent entry of coxsackievirus B into human placental trophoblasts. 
  • Neonate with coxsackie B1 infection, cardiomyopathy and arrhythmias. 
  • Persistent and fatal central-nervous-system ECHOvirus infections in patients with agammaglobulinemia. 
  • Poly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sites. 
  • Predictors of outcome of myocarditis. 
  • RIP3 Regulates Autophagy and Promotes Coxsackievirus B3 Infection of Intestinal Epithelial Cells. 
  • RNAi screening in mammalian cells to identify novel host cell molecules involved in the regulation of viral infections. 
  • Requirement of MIP-1 alpha for an inflammatory response to viral infection. 
  • The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. 
  • The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. 
  • The immunity-related GTPase Irgm3 relieves endoplasmic reticulum stress response during coxsackievirus B3 infection via a PI3K/Akt dependent pathway. 
  • The neonatal Fc receptor is a pan-echovirus receptor. 
  • mRNA translation is compartmentalized to the endoplasmic reticulum following physiological inhibition of cap-dependent translation. 
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  Keywords of People

  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Allergy and Immunology