Subject Areas on Research
- A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome.
- AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice.
- Acclimation of C2C12 myoblasts to physiological glucose concentrations for in vitro diabetes research.
- Addressing cell-sourcing limitations with gene therapy.
- Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.
- Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression.
- Angiopoietin-1 enhances skeletal muscle regeneration in mice.
- Astaxanthin but not quercetin preserves mitochondrial integrity and function, ameliorates oxidative stress, and reduces heat-induced skeletal muscle injury.
- Caspase-3 dependent cleavage and activation of skeletal muscle phosphorylase b kinase.
- Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues.
- Cell therapy for heart failure: the need for a new therapeutic strategy.
- Control of muscle formation by the fusogenic micropeptide myomixer.
- Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.
- Curcumin Ameliorates Heat-Induced Injury through NADPH Oxidase-Dependent Redox Signaling and Mitochondrial Preservation in C2C12 Myoblasts and Mouse Skeletal Muscle.
- DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2.
- Deconstructing Pompe disease by analyzing single muscle fibers: to see a world in a grain of sand..
- Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing.
- Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest.
- Early de novo DNA methylation and prolonged demethylation in the muscle lineage.
- Effect of cyclic stretch on beta1D-integrin expression and activation of FAK and RhoA.
- Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle.
- Engineering human pluripotent stem cells into a functional skeletal muscle tissue.
- Functional assessment of myoblast transplantation for cardiac repair with magnetic resonance imaging.
- Gene expression during normal and FSHD myogenesis.
- Heparin mimicking polymer promotes myogenic differentiation of muscle progenitor cells.
- Homer modulates NFAT-dependent signaling during muscle differentiation.
- Insights from molecular signature of in vivo cardiac c-Kit(+) cells following cardiac injury and β-catenin inhibition.
- Invading, Leading and Navigating Cells in Caenorhabditis elegans : Insights into Cell Movement in Vivo .
- Local tissue geometry determines contractile force generation of engineered muscle networks.
- Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells.
- Modeling statin myopathy in a human skeletal muscle microphysiological system.
- Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: reasons for cautious optimism.
- Molecular, cellular, and pharmacological therapies for Duchenne/Becker muscular dystrophies.
- Myoblast proliferation and differentiation on fibronectin-coated self assembled monolayers presenting different surface chemistries.
- Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators.
- Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine.
- Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.
- Pharmacological Inhibition of Lysosomal Activity as a Method For Monitoring Thyroid Hormone-induced Autophagic Flux in Mammalian Cells In Vitro.
- Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction.
- Progress in therapy for Duchenne muscular dystrophy.
- RASSF4 is required for skeletal muscle differentiation.
- Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype.
- SOCS1, SOCS3, and PIAS1 promote myogenic differentiation by inhibiting the leukemia inhibitory factor-induced JAK1/STAT1/STAT3 pathway.
- Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma.
- Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment.
- Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.
- Skeletal muscle mitochondrial fragmentation and impaired bioenergetics from nutrient overload are prevented by carbon monoxide.
- Skeletal muscle protein synthesis and the abundance of the mRNA translation initiation repressor PDCD4 are inversely regulated by fasting and refeeding in rats.
- Streptozotocin induces G2 arrest in skeletal muscle myoblasts and impairs muscle growth in vivo.
- The Transcriptional Coactivator TAZ Is a Potent Mediator of Alveolar Rhabdomyosarcoma Tumorigenesis.
- The type III TGF-beta receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation.
- Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells.
- VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.
- Video-assisted thoracoscopic transplantation of myoblasts into the heart.
Keywords of People
- Linardic, Corinne Mary, Associate Professor of Pediatrics, Cell Biology
- O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology