Stem Cell Transplantation

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  Subject Areas on Research

  • 'Well, It's the Risk of the Unknown… Right?': A Qualitative Study of Perceived Risks and Benefits of HIV Cure Research in the United States. 
  • 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline. 
  • A Path Forward for Regenerative Medicine. 
  • A Phase 2 Randomized, Sham-Controlled Trial of Internal Carotid Artery Infusion of Autologous Bone Marrow-Derived ALD-401 Cells in Patients With Recent Stable Ischemic Stroke (RECOVER-Stroke). 
  • A device to facilitate limbal stem cell procurement from eye bank donor tissue for keratolimbal allograft procedures. 
  • A mechanism-based complementary screening approach for the amelioration and reversal of neurobehavioral teratogenicity. 
  • A multicenter pilot evaluation of the National Institutes of Health chronic graft-versus-host disease (cGVHD) therapeutic response measures: feasibility, interrater reliability, and minimum detectable change. 
  • A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke. 
  • A phase 3, randomized, double-blinded, active-controlled, unblinded standard of care study assessing the efficacy and safety of intramyocardial autologous CD34+ cell administration in patients with refractory angina: design of the RENEW study. 
  • A phase III, randomized, double-blind, placebo-controlled, study of iseganan for the reduction of stomatitis in patients receiving stomatotoxic chemotherapy. 
  • A prospective longitudinal multicenter study of coagulation in pediatric patients undergoing allogeneic stem cell transplantation. 
  • ABCB5 is a limbal stem cell gene required for corneal development and repair. 
  • ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration (ALLSTAR) Trial: Rationale and Design. 
  • ANZCCSG BabyBrain99; intensified systemic chemotherapy, second look surgery and involved field radiation in young children with central nervous system malignancy. 
  • Acute radiation injury: contingency planning for triage, supportive care, and transplantation. 
  • Adipokines, body fatness, and insulin resistance among survivors of childhood leukemia. 
  • Adoptive immunotherapy by allogeneic stem cell transplantation for metastatic renal cell carcinoma: a CALGB intergroup phase II study. 
  • Adult-derived stem cells and their potential for use in tissue repair and molecular medicine. 
  • Advance Care Planning and Palliative Care Specialists in Malignant Hematology and Stem-Cell Transplantation: On Why It Takes A Village. 
  • Advances in bioengineered conduits for peripheral nerve regeneration. 
  • Allogeneic Transplantation after Myeloablative Rituximab/BEAM ± Bortezomib for Patients with Relapsed/Refractory Lymphoid Malignancies: 5-Year Follow-Up Results. 
  • Amifostine protects against cisplatin-induced ototoxicity in children with average-risk medulloblastoma. 
  • Amniotic membrane use for management of corneal limbal stem cell deficiency. 
  • An avian model for the reversal of neurobehavioral teratogenicity with neural stem cells. 
  • Angiogenic therapy for coronary artery and peripheral arterial disease. 
  • Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. 
  • Antifungal therapy for invasive fungal diseases in allogeneic stem cell transplant recipients: an update. 
  • Archenteron precursor cells can organize secondary axial structures in the sea urchin embryo. 
  • Assessing surge capacity for radiation victims with marrow toxicity. 
  • Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials. 
  • B-cell function in severe combined immunodeficiency after stem cell or gene therapy: a review. 
  • Blood in the joint: effects of hemarthrosis on meniscus health and repair techniques. 
  • Bone marrow B cell precursor number after allogeneic stem cell transplantation and GVHD development. 
  • Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting. 
  • Can underpowered clinical trials be justified? 
  • Candida glabrata fungemia in transplant patients receiving voriconazole after fluconazole. 
  • Cardiac cell therapy in vitro: reproducible assays for comparing the efficacy of different donor cells. 
  • Cardiomyoplasty: the prospect of human stem cells. 
  • Cell therapy for heart failure: the need for a new therapeutic strategy. 
  • Cell-Based Therapy Restores Olfactory Function in an Inducible Model of Hyposmia. 
  • Cell-based interventions for neurologic conditions: ethical challenges for early human trials. 
  • Chronic graft-versus-host disease. 
  • Clinical challenges and images in GI. Invasive candidal enterocolitis. 
  • Clinical outcome of cerebrospinal fluid shunting for communicating hydrocephalus in mucopolysaccharidoses I, II, and III: a retrospective analysis of 13 patients. 
  • Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation. 
  • Combined bone allograft and adipose-derived stem cell autograft in a rabbit model. 
  • Comparison of intracardiac cell transplantation: autologous skeletal myoblasts versus bone marrow cells. 
  • Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens from allogeneic-stem-cell transplant recipients. 
  • Comparison of ¹²³I-metaiodobenzylguanidine (MIBG) and ¹³¹I-MIBG semi-quantitative scores in predicting survival in patients with stage 4 neuroblastoma: a report from the Children's Oncology Group. 
  • Continuous renal replacement therapy (CRRT) after stem cell transplantation. A report from the prospective pediatric CRRT Registry Group. 
  • Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain. 
  • Current State of Stem Cell Therapy for Ischemic Heart Disease. 
  • Dendritic cell recovery following nonmyeloablative allogeneic stem cell transplants. 
  • Depletion of host reactive T cells by photodynamic cell purging and prevention of graft versus host disease. 
  • Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies. 
  • Detailed analysis of cytomegalovirus (CMV)-specific T cells expanded for adoptive immunotherapy of CMV infection following allogeneic stem cell transplantation for malignant disease. 
  • Distinct Responses of Stem Cells to Telomere Uncapping-A Potential Strategy to Improve the Safety of Cell Therapy. 
  • Economic analysis of conventional-dose chemotherapy compared with high-dose chemotherapy plus autologous hematopoietic stem-cell transplantation for metastatic breast cancer. 
  • Editorial: Stem cell transplantation in autoimmune diseases (AID). 
  • Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma: A Randomized Clinical Trial. 
  • Effect of initial treatment on health-related quality of life in patients with newly diagnosed multiple myeloma without immediate stem cell transplant intent: results from the Connect® MM Registry. 
  • Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease. 
  • Emerging Concepts in Paracrine Mechanisms in Regenerative Cardiovascular Medicine and Biology. 
  • Emerging Therapies for Congestive Heart Failure. 
  • Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo. 
  • Endothelial progenitor cell therapy for atherosclerosis: the philosopher's stone for an aging population? 
  • Engineering human pluripotent stem cells into a functional skeletal muscle tissue. 
  • Enhancing stem cell therapy through genetic modification. 
  • Epithelial stem cells of the lung: privileged few or opportunities for many? 
  • Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium. 
  • Ethics: Moral issues of human-non-human primate neural grafting. 
  • Fatal Scopulariopsis brevicaulis infection in a paediatric stem-cell transplant patient treated with voriconazole and caspofungin and a review of Scopulariopsis infections in immunocompromised patients. 
  • First global consensus for evidence-based management of the hematopoietic syndrome resulting from exposure to ionizing radiation. 
  • Gene and cell-based therapies for heart disease. 
  • Gene therapy progress and prospects: RNA aptamers. 
  • Gene therapy: charting a future course--summary of a National Institutes of Health Workshop, April 12, 2013. 
  • Gene- and cell-based approaches for neurodegenerative disease. 
  • Genetic engineering and stem cells: combinatorial approaches for cardiac cell therapy. 
  • Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. 
  • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. 
  • Global Consensus on the Management of Limbal Stem Cell Deficiency. 
  • Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies. 
  • Granulocyte colony-stimulating factor "mobilized" peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high-dose chemotherapy. 
  • Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation. 
  • Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group. 
  • High-dose chemotherapy and hematopoietic support for patients with high-risk primary breast cancer and involvement of 4 to 9 lymph nodes. 
  • High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas. 
  • High-dose doxorubicin, etoposide, and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer. City of Hope Bone Marrow Oncology Team. 
  • Highlights of the 2007 Scientific Meeting of the Heart Failure Society of America: Washington, DC, September 16-19, 2007. 
  • House calls for stem cell transplant patients during the COVID-19 pandemic. 
  • Human lung stem cells: has the future arrived? 
  • Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. 
  • Hydrogels as carriers for stem cell transplantation. 
  • Identifying Treatments for Taste and Smell Disorders: Gaps and Opportunities. 
  • Immunomodulation in stem-cell transplantation. 
  • Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts. 
  • Important impact of gingival and periodontal conditions on outcomes in SCT recipients. 
  • In vivo comparison of biomineralized scaffold-directed osteogenic differentiation of human embryonic and mesenchymal stem cells. 
  • Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse. 
  • Incidence and clinical significance of cardiac biomarker elevation during stem cell mobilization, apheresis, and intramyocardial delivery: an analysis from ACT34-CMI. 
  • Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. 
  • Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. 
  • Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors. 
  • Isolated cerebrospinal fluid relapse of acute myeloid leukemia status post stem cell transplant: A neuroleukemiosis manifesting as polyneuropathy. 
  • Lenalidomide Maintenance After Autologous Stem-Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Meta-Analysis. 
  • Lenalidomide after stem-cell transplantation for multiple myeloma. 
  • Letter by Makkar et al regarding article, "Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions". 
  • Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo. 
  • Low plasma concentrations of retinol and alpha-tocopherol in hematopoietic stem cell transplant recipients: the effect of mucositis and the risk of infection. 
  • Lung stem cells: looking beyond the hype. 
  • Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice. 
  • Mantle cell lymphoma with plasma cell differentiation. 
  • Maribavir prophylaxis for prevention of cytomegalovirus infection in allogeneic stem cell transplant recipients: a multicenter, randomized, double-blind, placebo-controlled, dose-ranging study. 
  • Mechanically ventilated pediatric stem cell transplant recipients: effect of cord blood transplant and organ dysfunction on outcome. 
  • Mechanisms Contributing to the Progression of Ischemic and Nonischemic Dilated Cardiomyopathy: Possible Modulating Effects of Paracrine Activities of Stem Cells. 
  • Meningeosis myelomatosis. 
  • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. 
  • Modified simple limbal epithelial transplantation using cryopreserved amniotic membrane for unilateral limbal stem cell deficiency. 
  • Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: reasons for cautious optimism. 
  • Molecular, cellular, and pharmacological therapies for Duchenne/Becker muscular dystrophies. 
  • Morbidity and mortality of chronic GVHD after hematopoietic stem cell transplantation from HLA-identical siblings for patients with aplastic or refractory anemias. 
  • Morphologic examination of sequential bone marrow biopsies after nonmyeloablative stem cell transplantation complements molecular studies of donor engraftment. 
  • Multi-site evaluation of the BD Stem Cell Enumeration Kit for CD34(+) cell enumeration on the BD FACSCanto II and BD FACSCalibur flow cytometers. 
  • Multiple Myeloma, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology. 
  • Multiple myeloma. 
  • Multiple myeloma. Clinical practice guidelines in oncology. 
  • Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery. 
  • Natural killer cell-enriched donor lymphocyte infusions from A 3-6/6 HLA matched family member following nonmyeloablative allogeneic stem cell transplantation. 
  • Neutropenia Precautions for Children Receiving Chemotherapy or Stem Cell Transplantation for Cancer. 
  • New treatment approaches for osteonecrosis of the femoral head: an overview. 
  • Non-Hodgkin's lymphomas. 
  • Novel constructs for thrombin inhibition. 
  • Novel therapies for epilepsy in the pipeline. 
  • Outcomes of stem cell transplant patients with acute respiratory failure requiring mechanical ventilation in the United States. 
  • Palifermin for the reduction of acute GVHD: a randomized, double-blind, placebo-controlled trial. 
  • Parental perspectives on a behavioral health music intervention for adolescent/young adult resilience during cancer treatment: report from the children's oncology group. 
  • Pathogenesis and therapy of focal segmental glomerulosclerosis: an update. 
  • Perceptions of specialty palliative care and its role in pediatric stem cell transplant: A multidisciplinary qualitative study. 
  • Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord. 
  • Persistent Mycobacterium avium infection following nonmyeloablative allogeneic peripheral blood stem cell transplantation for interferon-gamma receptor-1 deficiency. 
  • Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant. 
  • Physically Associated Synthetic Hydrogels with Long-Term Covalent Stabilization for Cell Culture and Stem Cell Transplantation 
  • Pim1 Kinase Overexpression Enhances ckit+ Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine. 
  • Placental/umbilical cord blood for unrelated-donor bone marrow reconstitution: relevance of nucleated red blood cells. 
  • Postresectional Airway Fistula Occlusion via Stem-Cell Transplantation: Is It Oncologically Safe? 
  • Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair. 
  • Prevalence, predictors and outcomes of cardiopulmonary resuscitation in hospitalized adult stem cell transplant recipients in the United States: not just opening the black box but exploring an opportunity to optimize! 
  • Pseudo-Pelger-Huët anomaly induced by medications: a clinicopathologic study in comparison with myelodysplastic syndrome-related pseudo-Pelger-Huët anomaly. 
  • Pulmonary hypoplasia. 
  • Quantitative analysis of diffusion tensor imaging data in serial assessment of Krabbe disease. 
  • Reduced intensity versus myeloablative allogeneic stem cell transplantation for the treatment of acute myeloid leukemia, myelodysplastic syndrome and acute lymphoid leukemia. 
  • Regionalization of stem cell transplant procedures into teaching hospitals in United States: are we ready? 
  • Regionally-specified second trimester fetal neural stem cells reveals differential neurogenic programming. 
  • Reparative cell therapy for the heart: critical internal appraisal of the field in response to recent controversies. 
  • Reply to Strahilevitz and Shapira. 
  • Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation. 
  • Review of chronic graft-versus-host disease in children after allogeneic stem cell transplantation: nursing perspective. 
  • Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis. 
  • Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients. 
  • Selective elimination of alloreactivity from immunotherapeutic T cells by photodynamic cell purging and memory T-cell sorting. 
  • Semiquantitative mIBG scoring as a prognostic indicator in patients with stage 4 neuroblastoma: a report from the Children's oncology group. 
  • Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support. 
  • Severe pulmonary toxicity after myeloablative conditioning using total body irradiation: an assessment of risk factors. 
  • Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair. 
  • Spinal cord astrocytomas: progresses in experimental and clinical investigations for developing recovery neurobiology-based novel therapies. 
  • Stem Cell Therapy for Congenital Heart Disease: A Systematic Review. 
  • Stem Cell Transplantation and Informatics: Current Considerations. 
  • Stem cell therapies for heart disease: why do we need bioengineers? 
  • Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies. 
  • Stem cell therapies in cerebral palsy and autism spectrum disorder. 
  • Stem cell therapy for neurologic disorders: therapeutic potential of adipose-derived stem cells. 
  • Stem cell tourism and Canadian family physicians. 
  • Stem cell transplantation for multiple myeloma. 
  • Stem cells for the ischaemic heart. 
  • Stem cells in the treatment of stroke. 
  • Stories and Music for Adolescent/Young Adult Resilience During Transplant Partnerships: Strategies to Support Academic-Clinical Nurse Collaborations in Behavioral Intervention Studies. 
  • Subretinal Human Umbilical Tissue-Derived Cell Transplantation Preserves Retinal Synaptic Connectivity and Attenuates Müller Glial Reactivity. 
  • Superparamagnetic iron oxide labeling and transplantation of adipose-derived stem cells in middle cerebral artery occlusion-injured mice. 
  • Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain 
  • Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. 
  • The (Pluri)Potential of Cell Therapy for Heart Failure. 
  • The (Translational) Road Less Traveled. 
  • The Athena trials: Autologous adipose-derived regenerative cells for refractory chronic myocardial ischemia with left ventricular dysfunction. 
  • The Future of Skull Base Surgery: A View Through Tinted Glasses. 
  • The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models. 
  • The RENEW Trial: Efficacy and Safety of Intramyocardial Autologous CD34(+) Cell Administration in Patients With Refractory Angina. 
  • The effects of periurethral muscle-derived stem cell injection on leak point pressure in a rat model of stress urinary incontinence. 
  • The future of cardiothoracic anesthesia. 
  • The incidence of testicular recurrence in boys with acute leukemia treated with total body and testicular irradiation and stem cell transplantation. 
  • Therapeutic potential of endothelial progenitor cells in cardiovascular diseases. 
  • Tissue engraftment of hypoxic-preconditioned adipose-derived stem cells improves flap viability. 
  • To stop or not to stop: how much support should be provided to mechanically ventilated pediatric bone marrow and stem cell transplant patients? 
  • Transferrin receptor 1 is differentially required in lymphocyte development. 
  • Transplantation of embryonic stem cells into the infarcted mouse heart: formation of multiple cell types. 
  • Treating cancer with embryonic stem cells: rationale comes from aging studies. 
  • Treatment Journeys of Patients With Newly Diagnosed Multiple Myeloma (NDMM): Results From The Connect MM Registry. 
  • Triple-hit B-cell Lymphoma With MYC, BCL2, and BCL6 Translocations/Rearrangements: Clinicopathologic Features of 11 Cases. 
  • Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma. 
  • Universal masking in hospitals in the COVID-19 era: Is it time to consider shielding? 
  • Unrelated umbilical cord blood transplantation for an infant with beta-thalassemia major. 
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  Keywords of People

  • Bursac, Nenad, Professor of Biomedical Engineering, Biomedical Engineering
  • Chen, Jun, Professor of Medicine, Duke Cancer Institute
  • Choi, Taewoong, Assistant Professor of Medicine, Duke Cancer Institute
  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Lagoo, Anand Shreeram, Professor of Pathology, Pathology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Reed, Shelby Derene, Professor in Population Health Sciences, Duke Science & Society
  • Troy, Jesse David, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Velkey, John Matthew, Assistant Professor of the Practice of Medical Education in the Department of Cell Biology, Cell Biology