Iron-Binding Proteins
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Subject Areas on Research
- A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway.
- Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology.
- Analysis of the E399D mutation in SLC11A2.
- Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: a role for boron in iron transport in marine life.
- Bordetella pertussis FbpA binds both unchelated iron and iron siderophore complexes.
- Cloning, sequencing, and recombinant expression of the porcine inhibitor of carbonic anhydrase: a novel member of the transferrin family.
- Correlation of IgG autoantibodies against acetylcholine receptors and desmogleins in patients with pemphigus treated with steroid sparing agents or rituximab.
- DMT1 expression is increased in the lungs of hypotransferrinemic mice.
- Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy.
- Divalent metal transporter-1 decreases metal-related injury in the lung.
- Enhanced mobilization of iron from body stores in malnourished patients during intravenous nutritional support.
- Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice.
- Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.
- Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA.
- Genes that modify the hemochromatosis phenotype in mice.
- Increased leptin levels correlate with thyroid autoantibodies in nonobese males.
- Iron homeostasis in the lung.
- Iron is hot: an update on the pathophysiology of hemochromatosis.
- Iron metabolism in mice with partial frataxin deficiency.
- Iron transport across biologic membranes.
- Iron uptake and Nramp2/DMT1/DCT1 in human bronchial epithelial cells.
- Iron-dependent regulation of the divalent metal ion transporter.
- Isolation, purification and characterization of an iron-binding protein from the horseshoe crab (Limulus polyphemus).
- Kinetics and mechanism of exogenous anion exchange in FeFbpA-NTA: significance of periplasmic anion lability and anion binding activity of ferric binding protein A.
- Kinetics and mechanism of iron release from the bacterial ferric binding protein nFbp: exogenous anion influence and comparison with mammalian transferrin.
- Kinetics and mechanism of iron(III) complexation by ferric binding protein: the role of phosphate.
- Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport.
- Mammalian iron transport: an unexpected link between metal homeostasis and host defense.
- Metabolic capacity regulates iron homeostasis in endothelial cells.
- Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene.
- Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue.
- Monomeric yeast frataxin is an iron-binding protein.
- Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.
- Progressive mitochondrial protein lysine acetylation and heart failure in a model of Friedreich's ataxia cardiomyopathy.
- Role of citrate and phosphate anions in the mechanism of iron(III) sequestration by ferric binding protein: kinetic studies of the formation of the holoprotein of wild-type FbpA and its engineered mutants.
- Scara5 is a ferritin receptor mediating non-transferrin iron delivery.
- Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver.
- TNF, IFN-gamma, and endotoxin increase expression of DMT1 in bronchial epithelial cells.
- The G185R mutation disrupts function of the iron transporter Nramp2.
- The Nramp2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border.
- The iron cycle and oxidative stress in the lung.
- The iron transporter DMT1.