Thrombopoiesis

• 

  Subject Areas on Research

  • Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage. 
  • Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes. 
  • Role of growth factors and thrombopoietic agents in the treatment of chronic hepatitis C. 
  • Transcriptional diversity during lineage commitment of human blood progenitors.