Sus scrofa

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  Subject Areas on Research

  • 3-Dimensional spatially organized PEG-based hydrogels for an aortic valve co-culture model. 
  • A biomechanical role for perlecan in the pericellular matrix of articular cartilage. 
  • A conformal, bio-interfaced class of silicon electronics for mapping cardiac electrophysiology. 
  • A nitric oxide processing defect of red blood cells created by hypoxia: deficiency of S-nitrosohemoglobin in pulmonary hypertension. 
  • A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy. 
  • A novel method for teaching key steps of strabismus surgery in the wet lab. 
  • A novel ultrasound technique to estimate right ventricular geometry during fibrillation. 
  • Adeno-associated viral vectors based on serotype 3b use components of the fibroblast growth factor receptor signaling complex for efficient transduction. 
  • Adjustable-Loop Femoral Cortical Suspensory Fixation for Patellar Tendon Anterior Cruciate Ligament Reconstruction: A Time Zero Biomechanical Comparison With Interference Screw Fixation. 
  • An endovascular model of ischemic myopathy from peripheral arterial disease. 
  • Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells 
  • Animal models in the research of abdominal aortic aneurysms development. 
  • Ankyrin-B structurally defines terminal microdomains of peripheral somatosensory axons. 
  • Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation. 
  • Apixaban Versus Warfarin for Mechanical Heart Valve Thromboprophylaxis in a Swine Aortic Heterotopic Valve Model. 
  • Assessment of a modified acoustic lens for electromagnetic shock wave lithotripters in a swine model. 
  • Bariatric Embolization: Pilot Study on the Impact of Gastroprotective Agents and Arterial Distribution on Ulceration Risk and Efficacy in a Porcine Model. 
  • Bariatric Radioembolization: A Pilot Study on Technical Feasibility and Safety in a Porcine Model. 
  • Biodegradable nanoparticle-entrapped vaccine induces cross-protective immune response against a virulent heterologous respiratory viral infection in pigs. 
  • Cardiac myocyte p38α kinase regulates angiogenesis via myocyte-endothelial cell cross-talk during stress-induced remodeling in the heart. 
  • Combined lipid emulsion and ACLS resuscitation following bupivacaine- and hypoxia-induced cardiovascular collapse in unanesthetized swine. 
  • Comparison of a novel radially dilating balloon ureteral access sheath to a conventional sheath in the porcine model. 
  • Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. 
  • Decellularized native and engineered arterial scaffolds for transplantation. 
  • Doxorubicin-loaded protease-activated near-infrared fluorescent polymeric nanoparticles for imaging and therapy of cancer. 
  • Drained secant modulus for human and porcine peripapillary sclera using unconfined compression testing. 
  • Early Identification of Acute Lung Injury in a Porcine Model of Hemorrhagic Shock. 
  • Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds. 
  • Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction. 
  • Estimation of the transverse strain tensor in the arterial wall using ivus image registration 
  • Evaluating the bioaccessibility of flame retardants in house dust using an in vitro Tenax bead-assisted sorptive physiologically based method. 
  • Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc. 
  • Extended hepatectomy using the bipolar tissue sealer: an experimental model of small-for-size syndrome in pigs. 
  • Functional vagotopy in the cervical vagus nerve of the domestic pig: implications for the study of vagus nerve stimulation. 
  • Gene delivery approaches to heart failure treatment. 
  • Human-Mediated Admixture and Selection Shape the Diversity on the Modern Swine (Sus scrofa) Y Chromosomes. 
  • ICG angiography predicts burn scarring within 48 h of injury in a porcine vertical progression burn model. 
  • Identification and quantification of dolichol and dolichoic acid in neuromelanin from substantia nigra of the human brain. 
  • Immunofluorescence-guided atomic force microscopy to measure the micromechanical properties of the pericellular matrix of porcine articular cartilage. 
  • Improving the lens design and performance of a contemporary electromagnetic shock wave lithotripter. 
  • Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering. 
  • Increasing dwell time of mitomycin C in the upper tract with a reverse thermosensitive polymer. 
  • Ineffectiveness of remote ischemic renal preconditioning in a porcine solitary-kidney model. 
  • Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis. 
  • Integrating valve-inspired design features into poly(ethylene glycol) hydrogel scaffolds for heart valve tissue engineering. 
  • Integration of a spectral domain optical coherence tomography system into a surgical microscope for intraoperative imaging. 
  • Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. 
  • Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. 
  • Major hepatic trauma: warm ischemic tolerance of the liver after hemorrhagic shock. 
  • Microwave versus saline-linked radiofrequency (Aquamantys) assisted liver resection in a porcine liver resection model. A safety and feasibility pilot study. 
  • Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region. 
  • Non-invasive vesicoureteral reflux detection: heating risk studies for a new device. 
  • Novel emboli protection cannula during cardiac surgery: first animal study. 
  • Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. 
  • PLGA nanoparticle entrapped killed porcine reproductive and respiratory syndrome virus vaccine helps in viral clearance in pigs. 
  • Pathologic evaluation of hemostatic agents in percutaneous nephrolithotomy tracts in a porcine model. 
  • Porcine global flash multifocal electroretinogram: possible mechanisms for the glaucomatous changes in contrast response function. 
  • Porcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigs. 
  • Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. 
  • Real-time sonoelastography of hepatic thermal lesions in a swine model. 
  • Sources of off-target effects of vagus nerve stimulation using the helical clinical lead in domestic pigs. 
  • Tezosentan normalizes hepatomesenteric perfusion in a porcine model of cardiac tamponade. 
  • The Haemophilus ducreyi trimeric autotransporter adhesin DsrA protects against an experimental infection in the swine model of chancroid. 
  • The biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells: EPC-seeded antithrombotic Ti implants. 
  • The effect of irrigation solution at different temperatures on articular cartilage metabolism. 
  • The effect of nitric oxide surface flux on the foreign body response to subcutaneous implants. 
  • The effects of adipokines on cartilage and meniscus catabolism. 
  • The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs. 
  • The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF 
  • The temperature-dependent viscoelasticity of porcine lumbar spine ligaments. 
  • Thromboembolic Events with Enterprise Versus Pipeline: Porcine In Vivo Experiment. 
  • Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration. 
  • Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. 
  • Traumatic brain injury and hemorrhagic shock: evaluation of different resuscitation strategies in a large animal model of combined insults. 
  • Video-assisted thoracoscopic transplantation of myoblasts into the heart. 
  • White matter tract-oriented deformation predicts traumatic axonal brain injury and reveals rotational direction-specific vulnerabilities. 
  • sCD44 overexpression increases intraocular pressure and aqueous outflow resistance. 
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  Keywords of People

  • Farsiu, Sina, Professor in the Department of Biomedical Engineering, Electrical and Computer Engineering
  • Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology