Nuclear Matrix-Associated Proteins

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  Subject Areas on Research

  • Assessment of autoantibodies to meningioma in a population-based study. 
  • Autosomal-dominant distal myopathy associated with a recurrent missense mutation in the gene encoding the nuclear matrix protein, matrin 3. 
  • High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation. 
  • High-content imaging-based screening of microenvironment-induced changes to stem cells. 
  • Rae1 interaction with NuMA is required for bipolar spindle formation. 
  • Sequence divergence of coiled coils--structural rods, myosin filament packing, and the extraordinary conservation of cohesins. 
  • The composition and morphology of yeast nuclear scaffolds. 
  • Two serologic markers to monitor the engraftment, growth, and treatment response of human leukemias in severe combined immunodeficient mice.