Antigens, Nuclear
-
Subject Areas on Research
- Acute myeloid leukemia ontogeny is defined by distinct somatic mutations.
- Antibodies against retroviral proteins and nuclear antigens in a subset of idiopathic CD4+ T lymphocytopenia patients.
- Antinuclear antibodies and nuclear antigens in NZB myeloma ascitic fluids.
- Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue.
- Assessment of autoantibodies to meningioma in a population-based study.
- B lymphocytes and systemic lupus erythematosus.
- Ependymomas: MIB-1 proliferation index and survival.
- Genetic variants of the nonhomologous end joining gene LIG4 and severe radiation pneumonitis in nonsmall cell lung cancer patients treated with definitive radiotherapy.
- Gliomas of the optic nerve: histological, immunohistochemical (MIB-1 and p53), and MRI analysis.
- High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation.
- High-content imaging-based screening of microenvironment-induced changes to stem cells.
- March 2000: A 16 year old female with a cerebellar mass.
- Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens.
- Prognostic risk factors that identify patients with clinical stage I nonseminomatous germ cell tumors at low risk and high risk for metastasis.
- Prognostic value of MIB-1 in advanced ovarian carcinoma as determined using automated immunohistochemistry and quantitative image analysis.
- Protein expression of p53, bcl-2, and KI-67 (MIB-1) as prognostic biomarkers in patients with surgically treated, clinically localized prostate cancer.
- Rae1 interaction with NuMA is required for bipolar spindle formation.
- Sequence divergence of coiled coils--structural rods, myosin filament packing, and the extraordinary conservation of cohesins.
- The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae.
- The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome.
- Use of phage display to identify novel mineralocorticoid receptor-interacting proteins.
-
Keywords of People
- Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
- McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Pharmacology & Cancer Biology
- McLendon, Roger Edwin, Professor of Pathology, Pathology