Telomeric Repeat Binding Protein 2
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Subject Areas on Research
- Distinct functions of POT1 at telomeres.
- Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.
- Loss of hPot1 function leads to telomere instability and a cut-like phenotype.
- Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function.
- POT1 association with TRF2 regulates telomere length.
- Putative telomere-recruiting domain in the catalytic subunit of human telomerase.
- Telomere dysfunction causes alveolar stem cell failure.
- Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation.
- The protein hSnm1B is stabilized when bound to the telomere-binding protein TRF2.
- The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response.
- hSnm1B is a novel telomere-associated protein.