Transcription Factor TFIID

• 

  Subject Areas on Research

  • A yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters. 
  • Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters. 
  • Promoting developmental transcription. 
  • Sp1 activation of a TATA-less promoter requires a species-specific interaction involving transcription factor IID. 
  • TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations. 
  • The DPE, a conserved downstream core promoter element that is functionally analogous to the TATA box. 
  • The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. 
  • The MTE, a new core promoter element for transcription by RNA polymerase II. 
  • The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery. 
  • The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. 
  • Transcriptional trans activation by human immunodeficiency virus type 1 Tat requires specific coactivators that are not basal factors.