Transcriptional Elongation Factors

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  Subject Areas on Research

  • A Bayesian approach for determining protein side-chain rotamer conformations using unassigned NOE data. 
  • Charged residues on the side of the nucleosome contribute to normal Spt16-gene interactions in budding yeast. 
  • Noncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant Cells. 
  • Pol II docking and pausing at growth and stress genes in C. elegans. 
  • Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non-small cell lung cancer in the PLCO cancer screening trial. 
  • Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II. 
  • Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat. 
  • Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome. 
  • Use of phage display to identify novel mineralocorticoid receptor-interacting proteins. 
  • Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.