MicroRNAs

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  Subject Areas on Research

  • miR-146a -Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression. 
  • A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking. 
  • A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. 
  • A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily. 
  • A TGF-β1 genetic variant at the miRNA187 binding site significantly modifies risk of HPV16-associated oropharyngeal cancer. 
  • A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. 
  • A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes. 
  • A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. 
  • A densely interconnected genome-wide network of microRNAs and oncogenic pathways revealed using gene expression signatures. 
  • A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer. 
  • A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk of recurrence in patients with oropharyngeal cancer. 
  • A functional variant at miRNA-122 binding site in IL-1α 3' UTR predicts risk and HPV-positive tumours of oropharyngeal cancer. 
  • A functional variant at the miR-184 binding site in TNFAIP2 and risk of squamous cell carcinoma of the head and neck. 
  • A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer. 
  • A functional variant at the miRNA binding site in E2F1 gene is associated with risk and tumor HPV16 status of oropharynx squamous cell carcinoma. 
  • A genetic variant within MDM4 3'UTR miRNA binding site is associated with HPV16-positive tumors and survival of oropharyngeal cancer. 
  • A genome-wide survey of copy number variations in Han Chinese residing in Taiwan. 
  • A large-scale survey of genetic copy number variations among Han Chinese residing in Taiwan. 
  • A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division. 
  • A microRNA signature profile in EBV+ diffuse large B-cell lymphoma of the elderly. 
  • A new way to see RNAs. 
  • A novel Cbx1, PurB, and Sp3 complex mediates long-term silencing of tissue- and lineage-specific genes. 
  • A precision medicine approach to stress testing using metabolomics and microribonucleic acids. 
  • A pri-miR-218 variant and risk of cervical carcinoma in Chinese women. 
  • A statin-regulated microRNA represses human c-Myc expression and function. 
  • A stele-enriched gene regulatory network in the Arabidopsis root. 
  • A variant at a potentially functional microRNA-binding site in BRIP1 was associated with risk of squamous cell carcinoma of the head and neck. 
  • A viral microRNA functions as an orthologue of cellular miR-155. 
  • AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma. 
  • ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category. 
  • Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. 
  • Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice. 
  • Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells. 
  • Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model. 
  • Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis. 
  • Altered lymphopoiesis and immunodeficiency in miR-142 null mice. 
  • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. 
  • An integrated approach to the prediction of chemotherapeutic response in patients with breast cancer. 
  • An introduction to small non-coding RNAs: miRNA and snoRNA. 
  • An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset. 
  • Analysis of "old" proteins unmasks dynamic gradient of cartilage turnover in human limbs. 
  • Angiogenin-mediated tRNA cleavage as a novel feature of stored red blood cells. 
  • Angiomirs expression profiling in diffuse large B-Cell lymphoma. 
  • Anti-fibrotic effects of different sources of MSC in bleomycin-induced lung fibrosis in C57BL6 male mice. 
  • Antisense inhibitors, ribozymes, and siRNAs. 
  • Apolipoprotein E isotype-dependent modulation of microRNA-146a in plasma and brain. 
  • Assessing the utility of thermodynamic features for microRNA target prediction under relaxed seed and no conservation requirements. 
  • Association between miRNA-binding site polymorphisms in double-strand break repair genes and risk of recurrence in patients with squamous cell carcinomas of the non-oropharynx. 
  • Association of genomic subtypes of lower-grade gliomas with shape features automatically extracted by a deep learning algorithm. 
  • Autophagy as a mechanism of antiviral defense at the maternal-fetal interface. 
  • BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • BCAT1 and miR-2504: novel methylome signature distinguishes spindle/desmoplastic melanoma from superficial malignant peripheral nerve sheath tumor. 
  • Biological clocks and the coordination theory of RNA operons and regulons. 
  • Biomarkers for kidney transplant rejection. 
  • Biomarkers of Diabetic Retinopathy. 
  • CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells. 
  • CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. 
  • Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells. 
  • Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B. 
  • Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. 
  • Cell signalling by microRNA165/6 directs gene dose-dependent root cell fate. 
  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. 
  • Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells. 
  • Cellular microRNAs correlate with clinical parameters in multiple injury patients. 
  • Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing. 
  • Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling. 
  • CircIRAK3 sponges miR-3607 to facilitate breast cancer metastasis. 
  • Circular RNA RSF1 promotes inflammatory and fibrotic phenotypes of irradiated hepatic stellate cell by modulating miR-146a-5p. 
  • Circulating microRNA expression profile: a novel potential predictor for chronic nervous lesions. 
  • Cis-acting polymorphisms affect complex traits through modifications of microRNA regulation pathways. 
  • Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma. 
  • Clinical and molecular markers of long-term survival after oligometastasis-directed stereotactic body radiotherapy (SBRT). 
  • Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity. 
  • Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer. 
  • Comprehensive molecular characterization of urothelial bladder carcinoma. 
  • Comprehensive molecular portraits of human breast tumours. 
  • Computational Analysis of Targeting SARS-CoV-2, Viral Entry Proteins ACE2 and TMPRSS2, and Interferon Genes by Host MicroRNAs. 
  • Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. 
  • Conserved microRNA program as key to mammalian cardiac regeneration: insights from zebrafish. 
  • Crosstalk in competing endogenous RNA networks reveals new circular RNAs involved in the pathogenesis of early HIV infection. 
  • Cullin-5, a ubiquitin ligase scaffold protein, is significantly underexpressed in endometrial adenocarcinomas and is a target of miR-182. 
  • DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest. 
  • DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. 
  • DNA copy number evolution in Drosophila cell lines. 
  • DNA methylation and miRNA expression profiling in childhood B-cell acute lymphoblastic leukemia. 
  • Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. 
  • Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. 
  • Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling. 
  • Detecting and characterizing circular RNAs. 
  • Differential expression of microRNAs among cell populations in the regenerating adult mouse olfactory epithelium. 
  • Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis. 
  • Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways. 
  • Differentially expressed microRNAs and affected biological pathways revealed by modulated modularity clustering (MMC) analysis of human preeclamptic and IUGR placentas. 
  • Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma. 
  • Direct SERDS sensing of molecular biomarkers in plants under field conditions. 
  • Direct and Label-Free Detection of MicroRNA Cancer Biomarkers using SERS-Based Plasmonic Coupling Interference (PCI) Nanoprobes. 
  • Direct reprogramming of cardiac fibroblasts to cardiomyocytes using microRNAs. 
  • Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis. 
  • Down-regulation of microRNAs controlling tumourigenic factors in follicular thyroid carcinoma. 
  • Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion. 
  • Dynamic microRNA gene transcription and processing during T cell development. 
  • Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies. 
  • Dysregulated activation of fetal liver programme in acute liver failure. 
  • Dysregulation of miR-181c expression influences recurrence of endometrial endometrioid adenocarcinoma by modulating NOTCH2 expression: An NRG Oncology/Gynecologic Oncology Group study. 
  • Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication. 
  • EBV-positive diffuse large B-cell lymphoma of the elderly. 
  • EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1. 
  • Editorial commentary: MicroRNAs as effectors and indicators of aspirin therapeutic potential. 
  • Effect of microRNA modulation on bioartificial muscle function. 
  • Effects of spaceflight on murine skeletal muscle gene expression. 
  • Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6. 
  • Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis. 
  • Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182. 
  • Epigenetics and psychostimulant addiction. 
  • Epithelial progenitor cells of the embryonic lung and the role of microRNAs in their proliferation. 
  • Essential Role of Non-Coding RNAs in Enterovirus Infection: From Basic Mechanisms to Clinical Prospects. 
  • Evaluation of microRNA expression in patient bone marrow aspirate slides. 
  • Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21. 
  • Exosome-Mediated Delivery of Inducible miR-423-5p Enhances Resistance of MRC-5 Cells to Rabies Virus Infection. 
  • Expression and trafficking of placental microRNAs at the feto-maternal interface. 
  • Expression of mRNAs, miRNAs, and lncRNAs in Human Trabecular Meshwork Cells Upon Mechanical Stretch. 
  • Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury. 
  • Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1. 
  • Extracellular vesicles from endometriosis patients are characterized by a unique miRNA-lncRNA signature. 
  • FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish. 
  • Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors. 
  • Functional variants in TNFAIP8 associated with cervical cancer susceptibility and clinical outcomes. 
  • Functional variants in the low-density lipoprotein receptor gene are associated with clear cell renal cell carcinoma susceptibility. 
  • Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. 
  • Gene Expression Signatures and the Spectrum of Coronary Artery Disease. 
  • Gene silencing using RNA interference in embryonic stem cells. 
  • Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies. 
  • Genetic polymorphisms in the microRNA binding-sites of the thymidylate synthase gene predict risk and survival in gastric cancer. 
  • Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ≤ 55 years. 
  • Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site. 
  • Genetic variants at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 
  • Genetic variants in miR-196a2 and miR-499 are associated with susceptibility to esophageal squamous cell carcinoma in Chinese Han population. 
  • Genetic variants in microRNA-binding sites of DNA repair genes as predictors of recurrence in patients with squamous cell carcinoma of the oropharynx. 
  • Genetic variants in selected pre-microRNA genes and the risk of squamous cell carcinoma of the head and neck. 
  • Genome-wide analysis of miRNA signature in the APPswe/PS1ΔE9 mouse model of alzheimer's disease. 
  • Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome. 
  • Genome-wide search for miRNA-target interactions in Arabidopsis thaliana with an integrated approach. 
  • Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer. 
  • Global analysis of microRNA target gene expression reveals that miRNA targets are lower expressed in mature mouse and Drosophila tissues than in the embryos. 
  • HDAC4 promotes Pax7-dependent satellite cell activation and muscle regeneration. 
  • HIF-1α inducing exosomal microRNA-23a expression mediates the cross-talk between tubular epithelial cells and macrophages in tubulointerstitial inflammation. 
  • HIF-miR-215-KDM1B promotes glioma-initiating cell adaptation to hypoxia. 
  • Hematopoietic stem cell transplantation for adults with T-cell lymphoblastic lymphoma: can we successfully step into the era of precision medicine? 
  • Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. 
  • High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease. 
  • High-resolution experimental and computational profiling of tissue-specific known and novel miRNAs in Arabidopsis. 
  • High-throughput intracellular biopsy of microRNAs for dissecting the temporal dynamics of cellular heterogeneity. 
  • HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis. 
  • Human aqueous humor exosomes. 
  • Human mesenchymal stem cells suppress the stretch-induced inflammatory miR-155 and cytokines in bronchial epithelial cells. 
  • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. 
  • Human placental trophoblasts confer viral resistance to recipient cells. 
  • Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. 
  • Hypercholesterolemia Increases Colorectal Cancer Incidence by Reducing Production of NKT and γδ T Cells from Hematopoietic Stem Cells. 
  • Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. 
  • IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C. 
  • Identification and Functional Validation of Reciprocal microRNA-mRNA Pairings in African American Prostate Cancer Disparities. 
  • Identification of a novel epigenetic regulatory region within the pluripotency associated microRNA cluster, EEmiRC. 
  • Identification of a serum microRNA expression signature for detection of lung cancer, involving miR-23b, miR-221, miR-148b and miR-423-3p. 
  • Identification of co-regulated transcripts affecting male body size in Drosophila. 
  • Identification of differentially expressed microRNAs in human hepatocellular adenoma associated with type I glycogen storage disease: a potential utility as biomarkers. 
  • Identification of wounding and topping responsive small RNAs in tobacco (Nicotiana tabacum). 
  • Identifying host microRNAs in bronchoalveolar lavage samples from lung transplant recipients infected with Aspergillus. 
  • In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. 
  • Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons. 
  • Increased miR-21-3p in Injured Brain Microvascular Endothelial Cells after Traumatic Brain Injury Aggravates Blood-Brain Barrier Damage by Promoting Cellular Apoptosis and Inflammation through Targeting MAT2B. 
  • Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury. 
  • Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells. 
  • Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells. 
  • Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis. 
  • Integrated genomic analyses of ovarian carcinoma. 
  • Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14. 
  • Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability. 
  • Intercellular communication during plant development. 
  • Intralingual Administration of AAVrh10-miRSOD1 Improves Respiratory But Not Swallowing Function in a Superoxide Dismutase-1 Mouse Model of Amyotrophic Lateral Sclerosis. 
  • Intraocular Medulloepitheliomas and Embryonal Tumors With Multilayered Rosettes of the Brain: Comparative Roles of LIN28A and C19MC. 
  • Inverse Molecular Sentinel-Integrated Fiberoptic Sensor for Direct and in Situ Detection of miRNA Targets. 
  • Iron-responsive miR-485-3p regulates cellular iron homeostasis by targeting ferroportin. 
  • Isolation and characterization of microRNAs of human mature erythrocytes. 
  • Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity. 
  • Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3. 
  • LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer. 
  • LIN28B promotes the development of neuroendocrine prostate cancer. 
  • Large-Scale microRNA Expression Profiling Identifies Putative Retinal miRNA-mRNA Signaling Pathways Underlying Form-Deprivation Myopia in Mice. 
  • Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3. 
  • Lin28b Regulates Fetal Regulatory T Cell Differentiation through Modulation of TGF-β Signaling. 
  • Long noncoding RNA MIR4435-2HG enhances metabolic function of myeloid dendritic cells from HIV-1 elite controllers. 
  • Long-Term Decrease of Intraocular Pressure in Rats by Viral Delivery of miR-146a. 
  • Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance. 
  • Loss of microRNA-21 leads to profound stromal remodeling and short survival in K-Ras-driven mouse models of pancreatic cancer. 
  • Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. 
  • Macrophage immunoregulatory pathways in tuberculosis. 
  • Macrophage-Derived MicroRNA-21 Drives Overwhelming Glycolytic and Inflammatory Response during Sepsis via Repression of the PGE2/IL-10 Axis. 
  • MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5. 
  • Mechanisms coordinating ELAV/Hu mRNA regulons. 
  • Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2. 
  • Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum. 
  • MiR-106a-5p modulates apoptosis and metabonomics changes by TGF-β/Smad signaling pathway in cleft palate. 
  • MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1. 
  • MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer. 
  • MiR-21 alleviates secondary blood-brain barrier damage after traumatic brain injury in rats. 
  • MiR-215 Is Induced Post-transcriptionally via HIF-Drosha Complex and Mediates Glioma-Initiating Cell Adaptation to Hypoxia by Targeting KDM1B. 
  • MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex. 
  • Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. 
  • Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines. 
  • MicroRNA binding-site polymorphisms as potential biomarkers of cancer risk. 
  • MicroRNA expression characterizes oligometastasis(es). 
  • MicroRNA expression differentiates squamous epithelium from Barrett's esophagus and esophageal cancer. 
  • MicroRNA expression profiles differentiate chronic pain condition subtypes. 
  • MicroRNA expression profiling using microarrays. 
  • MicroRNA induced cardiac reprogramming in vivo: evidence for mature cardiac myocytes and improved cardiac function. 
  • MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2. 
  • MicroRNA miR396 Regulates the Switch between Stem Cells and Transit-Amplifying Cells in Arabidopsis Roots. 
  • MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium. 
  • MicroRNA regulation and interspecific variation of gene expression. 
  • MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model. 
  • MicroRNA variants increase the risk of HPV-associated squamous cell carcinoma of the oropharynx in never smokers. 
  • MicroRNA, the putative molecular control for mid-life decline. 
  • MicroRNA-122 associates with serum apolipoprotein B but not liver fibrosis markers in CHC genotype 1 infection. 
  • MicroRNA-146a-5p Attenuates Fibrosis-related Molecules in Irradiated and TGF-beta1-Treated Human Hepatic Stellate Cells by Regulating PTPRA-SRC Signaling. 
  • MicroRNA-155 controls vincristine sensitivity and predicts superior clinical outcome in diffuse large B-cell lymphoma. 
  • MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma. 
  • MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice. 
  • MicroRNA-182 and microRNA-200a control G-protein subunit α-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. 
  • MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes. 
  • MicroRNA-23a Curbs Necrosis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium. 
  • MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation. 
  • MicroRNA-31 controls G protein alpha-13 (GNA13) expression and cell invasion in breast cancer cells. 
  • MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3. 
  • MicroRNA-34a enhances T cell activation by targeting diacylglycerol kinase ζ. 
  • MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma. 
  • MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling. 
  • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. 
  • MicroRNAs and Cardiac Regeneration. 
  • MicroRNAs associated to single drug components of R-CHOP identifies diffuse large B-cell lymphoma patients with poor outcome and adds prognostic value to the international prognostic index. 
  • MicroRNAs both promote and antagonize longevity in C. elegans. 
  • MicroRNAs in endometrial cancers from black and white patients. 
  • MicroRNAs in placental health and disease. 
  • MicroRNAs in skin tissue engineering. 
  • MicroRNAs preferentially target the genes with high transcriptional regulation complexity. 
  • MicroRNAs relate to early worsening of renal function in patients with acute heart failure. 
  • MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes. 
  • Microenvironmental regulation of cancer metastasis by miRNAs. 
  • Mining database for the expression and gene regulation network of JAK2 in skin cutaneous melanoma. 
  • Molecular biology: microRNA is here to stay. 
  • Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation. 
  • Molecular genetic mechanisms of allelic specific regulation of murine Comt expression. 
  • Molecular markers for incidence, prognosis, and response to therapy. 
  • Monocyte miRNAs Are Associated With Type 2 Diabetes. 
  • Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. 
  • Mycobacterium tuberculosis decreases human macrophage IFN-γ responsiveness through miR-132 and miR-26a. 
  • Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b. 
  • Myogenic transcription factors regulate pro-metastatic miR-182. 
  • N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway. 
  • NCCN task force report: molecular markers in leukemias and lymphomas. 
  • Negative regulation of the tumor suppressor p53 gene by microRNAs. 
  • Network calisthenics: control of E2F dynamics in cell cycle entry. 
  • Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories. 
  • New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing. 
  • New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis. 
  • New regulators of vertebrate appendage regeneration. 
  • Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association. 
  • Noncoding RNAs: biology and applications-a Keystone Symposia report. 
  • Novel Transcriptional Mechanisms for Regulating Metabolism by Thyroid Hormone. 
  • Oncogene-dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma. 
  • Optimizing delivery for efficient cardiac reprogramming. 
  • PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data. 
  • POWRS: position-sensitive motif discovery. 
  • Parallel Multi-Omics in High-Risk Subjects for the Identification of Integrated Biomarker Signatures of Type 1 Diabetes. 
  • Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. 
  • Patterns of microRNA expression characterize stages of human B-cell differentiation. 
  • Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR. 
  • Phase separation of chromatin and small RNA pathways in plants. 
  • Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL). 
  • Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support. 
  • Plasma MicroRNAs in Established Rheumatoid Arthritis Relate to Adiposity and Altered Plasma and Skeletal Muscle Cytokine and Metabolic Profiles. 
  • Plasma biomarkers for distinguishing etiologic subtypes of thoracic aortic aneurysm disease. 
  • Plasma miRNAs as early biomarkers for detecting hepatocellular carcinoma. 
  • Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. 
  • Plasma microRNA-586 is a new biomarker for acute graft-versus-host disease. 
  • Plasmonic Nanoprobes for in Vivo Multimodal Sensing and Bioimaging of MicroRNA within Plants. 
  • Plasmonic coupling interference (PCI) nanoprobes for nucleic acid detection. 
  • Plasmonic nanobiosensors for detection of microRNA cancer biomarkers in clinical samples. 
  • Platelet RNA as a novel biomarker for the response to antiplatelet therapy. 
  • Platelet microparticle delivered microRNA-Let-7a promotes the angiogenic switch. 
  • Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression. 
  • Polymorphisms at the microRNA binding-site of the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer. 
  • Polymorphisms in MicroRNAs are associated with survival in non-small cell lung cancer. 
  • Polymorphisms in microRNA targets: a gold mine for molecular epidemiology. 
  • Post-transcriptional regulation of MTA family by microRNAs in the context of cancer. 
  • Postoperative prognosis prediction of pancreatic cancer with seven microRNAs. 
  • Potency analysis of cellular therapies: the emerging role of molecular assays. 
  • Potential role of Hedgehog signaling and microRNA-29 in liver fibrosis of IKKβ-deficient mouse. 
  • Pre-miRNA variants as predictors of clinical outcome in patients with squamous cell carcinomas of the nonoropharynx. 
  • Pre-microRNA variants predict HPV16-positive tumors and survival in patients with squamous cell carcinoma of the oropharynx. 
  • Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. 
  • Primary tumor microRNA signature predicts recurrence and survival in patients with locally advanced esophageal adenocarcinoma. 
  • Principles of microRNA regulation of a human cellular signaling network. 
  • Production of Cardiomyocytes by microRNA-Mediated Reprogramming in Optimized Reprogramming Media. 
  • Profiling MicroRNAs with Associated Spatial Dynamics in Acute Tissue Slices. 
  • Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. 
  • Progesterone Resistance in Endometriosis Is Modulated by the Altered Expression of MicroRNA-29c and FKBP4. 
  • Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia. 
  • Prognostic factors, therapeutic approaches, and distinct immunobiologic features in patients with primary mediastinal large B-cell lymphoma on long-term follow-up. 
  • Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer. 
  • Prospective gene signature study using microRNA to identify the tissue of origin in patients with carcinoma of unknown primary. 
  • Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network. 
  • Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq. 
  • RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure. 
  • REV3L 3'UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility. 
  • RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. 
  • RNA-binding protein DUS16 plays an essential role in primary miRNA processing in the unicellular alga Chlamydomonas reinhardtii. 
  • RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures. 
  • Rationale and design of a multicenter randomized clinical trial of vestibulodynia: understanding pathophysiology and determining appropriate treatments (vestibulodynia: UPDATe). 
  • Regulation of PP2Cm expression by miRNA-204/211 and miRNA-22 in mouse and human cells. 
  • Regulation of T cell function by microRNA-720. 
  • Regulation of mast cell survival and function by tuberous sclerosis complex 1. 
  • Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. 
  • Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c. 
  • Regulation of zebrafish heart regeneration by miR-133. 
  • Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. 
  • Restriction of big hearts by a small RNA. 
  • Review: placenta-specific microRNAs in exosomes - good things come in nano-packages. 
  • SUMO2/3 conjugation is an endogenous neuroprotective mechanism. 
  • Scleral micro-RNA signatures in adult and fetal eyes. 
  • Screening of the Seed Region of MIR184 in Keratoconus Patients from Saudi Arabia. 
  • Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. 
  • Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog. 
  • Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. 
  • Serum inflammatory miRNAs predict radiation esophagitis in patients receiving definitive radiochemotherapy for non-small cell lung cancer. 
  • Serum miR-638 Combined with Squamous Cell Carcinoma-Related Antigen as Potential Screening Biomarkers for Cervical Squamous Cell Carcinoma. 
  • Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls. 
  • Signature of circulating microRNAs in patients with acute heart failure. 
  • Significance of microRNA-related variants in susceptibility to recurrence of oropharyngeal cancer patients after definitive radiotherapy. 
  • Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program. 
  • Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival. 
  • Small ubiquitin-like modifier 1-3 conjugation [corrected] is activated in human astrocytic brain tumors and is required for glioblastoma cell survival. 
  • Smartphone-Based Device for Colorimetric Detection of MicroRNA Biomarkers Using Nanoparticle-Based Assay. 
  • Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. 
  • Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. 
  • Spatial preferences of microRNA targets in 3' untranslated regions. 
  • Spatiotemporal signalling in plant development. 
  • Stereotactic body radiotherapy for oligometastatic breast cancer: a new standard of care, or a medical reversal in waiting? 
  • Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. 
  • Suppression of the microRNA pathway by bacterial effector proteins. 
  • Sustained-input switches for transcription factors and microRNAs are central building blocks of eukaryotic gene circuits. 
  • Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. 
  • T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation. 
  • TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study. 
  • TGF-β-Regulated MicroRNAs and Their Function in Cancer Biology. 
  • TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma. 
  • TP53 dysfunction in diffuse large B-cell lymphoma. 
  • Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression. 
  • Targeting the Wnt-Regulatory Protein CTNNBIP1 by microRNA-214 Enhances the Stemness and Self-Renewal of Cancer Stem-Like Cells in Lung Adenocarcinomas. 
  • The Cancer Genome Atlas expression profiles of low-grade gliomas. 
  • The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells. 
  • The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cis. 
  • The Function of TrophomiRs and Other MicroRNAs in the Human Placenta. 
  • The MicroRNA miR-191 Supports T Cell Survival Following Common γ Chain Signaling. 
  • The cholinergic anti-inflammatory pathway meets microRNA. 
  • The colorectal microRNAome. 
  • The combination of TPL2 knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines. 
  • The current epidemiology and clinical decisions surrounding acute respiratory infections. 
  • The effects of heparins on the liver: application of mechanistic serum biomarkers in a randomized study in healthy volunteers. 
  • The expression level of C19MC miRNAs in early pregnancy and in response to viral infection. 
  • The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs. 
  • The genetic landscape of the childhood cancer medulloblastoma. 
  • The genome of a songbird. 
  • The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. 
  • The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy. 
  • The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer. 
  • The microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder. 
  • The oncogenic microRNA miR-21 promotes regulated necrosis in mice. 
  • The role of CAF derived exosomal microRNAs in the tumour microenvironment of melanoma. 
  • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. 
  • The role of microRNAs in Epstein-Barr virus latency and lytic reactivation. 
  • The role of microRNAs in glaucoma. 
  • The role of trophoblastic microRNAs in placental viral infection. 
  • The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. 
  • The viral and cellular microRNA targetome in lymphoblastoid cell lines. 
  • The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. 
  • Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells. 
  • Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. 
  • Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs. 
  • Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant. 
  • To grow or not to grow: nutritional control of development during Caenorhabditis elegans L1 arrest. 
  • Trans-kingdom small RNA transfer during host-pathogen interactions: The case of P. falciparum and erythrocytes. 
  • Transcriptome profiling of genes involved in neural tube closure during human embryonic development using long serial analysis of gene expression (long-SAGE). 
  • Transcriptome, genetic editing, and microRNA divergence substantiate sympatric speciation of blind mole rat, Spalax. 
  • Transcriptomic analysis of peripheral blood mononuclear cells in rapid progressors in early HIV infection identifies a signature closely correlated with disease progression. 
  • Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. 
  • Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance. 
  • Treatment of HCV infection by targeting microRNA. 
  • Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. 
  • Unc-13 homolog D mediates an antiviral effect of the chromosome 19 microRNA cluster miR-517a. 
  • Unexpected positive control of NFκB and miR-155 by DGKα and ζ ensures effector and memory CD8+ T cell differentiation. 
  • Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. 
  • Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis. 
  • Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure. 
  • Use of viral systems to study miRNA-mediated regulation of gene expression in human cells. 
  • Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. 
  • Viral Micro-RNAs Are Detected in the Early Systemic Response to Injury and Are Associated With Outcomes in Polytrauma Patients. 
  • Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. 
  • Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus. 
  • [Relationship between Helicobacter pylori infection and miR-24-3p expression during the development of gastric mucosa lesions]. 
  • miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. 
  • miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β. 
  • miR-149 and miR-29c as candidates for bipolar disorder biomarkers. 
  • miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy. 
  • miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation. 
  • miR-181a is an intrinsic modulator of T cell sensitivity and selection. 
  • miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. 
  • miR-19 is a key oncogenic component of mir-17-92. 
  • miR-203, a tumor suppressor frequently down-regulated by promoter hypermethylation in rhabdomyosarcoma. 
  • miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy. 
  • miR-21 improves the neurological outcome after traumatic brain injury in rats. 
  • miR-21-5p: A viable therapeutic strategy for regulating intraocular pressure. 
  • miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1. 
  • miR-301a as an NF-κB activator in pancreatic cancer cells. 
  • miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia. 
  • miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways. 
  • miR-34a is a microRNA safeguard for Citrobacter-induced inflammatory colon oncogenesis. 
  • miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population. 
  • miRNA Profile in Three Different Normal Human Ocular Tissues by miRNA-Seq. 
  • miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy. 
  • miRNA probe integrated biosensor platform using bimetallic nanostars for amplification-free multiplexed detection of circulating colorectal cancer biomarkers in clinical samples. 
  • miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus. 
  • microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. 
  • microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function. 
  • microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential. 
  • microRNA-214 promotes epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting the suppressor-of-fused protein (Sufu). 
  • microRNAs at the regulatory frontier: an investigation into how microRNAs impact the development and effector functions of CD4 T cells. 
  • mir-17-92: a polycistronic oncomir with pleiotropic functions. 
  • p38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neurons. 
  • p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma. 
  • β-arrestin1-biased β1-adrenergic receptor signaling regulates microRNA processing. 
• 

  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Ciofani, Maria, Associate Professor of Integrative Immunobiology, Cell Biology
  • Luftig, Micah Alan, Professor of Molecular Genetics and Microbiology, Cell Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Nackley, Andrea Gail, Associate Professor in Anesthesiology, Pharmacology & Cancer Biology
  • Tsalik, Ephraim, Adjunct Associate Professor in the Department of Medicine, Medicine, Infectious Diseases