Mannose-Binding Lectins

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  Subject Areas on Research

  • Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer. 
  • CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer. 
  • Calorimetric analysis of the binding of lectins with overlapping carbohydrate-binding ligand specificities. 
  • Characterization of Langerin-expressing dendritic cell subsets in the normal cornea. 
  • Down regulation of macrophage mannose/N-acetylglucosamine receptors by elevated glucose concentrations. 
  • Effect of modulating macrophage phenotype on peripheral nerve repair. 
  • GPI-defective monocytes from paroxysmal nocturnal hemoglobinuria patients show impaired in vitro dendritic cell differentiation. 
  • Protection against Escherichia coli-induced urinary tract infections with hybridoma antibodies directed against type 1 fimbriae or complementary D-mannose receptors. 
  • Recalcitrant rhinosinusitis, innate immunity, and mannose-binding lectin. 
  • Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili. 
  • The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins.