Integrin alpha5beta1
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Subject Areas on Research
- Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry.
- Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes.
- CLT1 targets bladder cancer through integrin α5β1 and CLIC3.
- Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.
- Cutting edge: Role of osteopontin and integrin αv in T cell-mediated anti-inflammatory responses in endotoxemia.
- Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells.
- Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability
- Smooth muscle cell rigidity and extracellular matrix organization influence endothelial cell spreading and adhesion formation in coculture.
- Trimers of the fibronectin cell adhesion domain localize to actin filament bundles and undergo rearward translocation.
- TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells.