Protein Array Analysis
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Subject Areas on Research
- A computational framework for the analysis of peptide microarray antibody binding data with application to HIV vaccine profiling.
- A phase I multi-institutional study of systemic sorafenib in conjunction with regional melphalan for in-transit melanoma of the extremity.
- A protein microarray-based analysis of S-nitrosylation.
- ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
- An overview of lung cancer genomics and proteomics.
- Analysing breast cancer microarrays from African Americans using shrinkage-based discriminant analysis.
- Autoantibody biomarkers identified by proteomics methods distinguish ovarian cancer from non-ovarian cancer with various CA-125 levels.
- Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies.
- BAFF-ling autoantibodies.
- Capture and release of proteins on the nanoscale by stimuli-responsive elastin-like polypeptide "switches".
- Cell culture block array for immunocytochemical study of protein expression in cultured cells.
- Clinical and therapeutic relevance of PIM1 kinase in gastric cancer.
- Comprehensive molecular portraits of human breast tumours.
- Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights.
- DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling.
- DNA repair phenotype and cancer susceptibility--a mini review.
- DNA-Templated Self-Assembly of Protein Arrays and Highly Conductive Nanowires
- Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays.
- Endothelial cell antibodies associated with novel targets and increased rejection.
- Evaluation of microarray surfaces and arraying parameters for autoantibody profiling.
- Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility.
- Expression of RON Proto-oncogene in Renal Oncocytoma and Chromophobe Renal Cell Carcinoma.
- Expression of nucleotide excision repair proteins in lymphocytes as a marker of susceptibility to squamous cell carcinomas of the head and neck.
- Fabrication of a reversible protein array directly from cell lysate using a stimuli-responsive polypeptide.
- Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome.
- Genetics of osteoarthritis.
- Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients.
- High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients.
- High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays.
- Identification and validation of a potential lung cancer serum biomarker detected by matrix-assisted laser desorption/ionization-time of flight spectra analysis.
- Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
- In vitro expression levels of cell-cycle checkpoint proteins are associated with cellular DNA repair capacity in peripheral blood lymphocytes: a multivariate analysis.
- Inflammatory protein profile during systemic high dose interleukin-2 administration.
- Invasion and MMP expression profile in desmoid tumours.
- Linking ligand-induced alterations in androgen receptor structure to differential gene expression: a first step in the rational design of selective androgen receptor modulators.
- Multi-analyte analysis system using an antibody-based biochip.
- Multiplexed protein array platforms for analysis of autoimmune diseases.
- Pancreatic cyst fluid protein expression profiling for discriminating between serous cystadenoma and intraductal papillary mucinous neoplasm.
- Pilot and feasibility study: prospective proteomic profiling of mammary epithelial cells from high-risk women provides evidence of activation of pro-survival pathways.
- Plasma biomarker profiles differ depending on breast cancer subtype but RANTES is consistently increased.
- Plasma biomarkers for distinguishing etiologic subtypes of thoracic aortic aneurysm disease.
- Polyreactivity and autoreactivity among HIV-1 antibodies.
- Prion disease diagnosis by proteomic profiling.
- Profiling heparin-chemokine interactions using synthetic tools.
- Profiling the dynamics of a human phosphorylome reveals new components in HGF/c-Met signaling.
- Protein array method for assessing in vitro biomaterial-induced cytokine expression.
- Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.
- Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data.
- Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer.
- Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiae.
- Proteomic analysis of stage I endometrial cancer tissue: identification of proteins associated with oxidative processes and inflammation.
- Quantitative modeling of transcription factor binding specificities using DNA shape.
- Rethinking Autoantibody Signature Panels for Cancer Diagnosis.
- Segment and fit thresholding: a new method for image analysis applied to microarray and immunofluorescence data.
- Serial dilution curve: a new method for analysis of reverse phase protein array data.
- Similar CD19 dysregulation in two autoantibody-associated autoimmune diseases suggests a shared mechanism of B-cell tolerance loss.
- Stability selection for regression-based models of transcription factor-DNA binding specificity.
- Survey of variation in human transcription factors reveals prevalent DNA binding changes.
- Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma.
- The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120.
- The protein expression landscape of the Arabidopsis root.
- The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA.
- Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer.
- Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways.
- Trefoil factor 3 immunohistochemical characterization of follicular thyroid lesions from tissue microarray.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Gordan, Raluca Mihaela, Associate Professor in Biostatistics & Bioinformatics, Computer Science
- Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
- Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
- Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology