Vascular Endothelial Growth Factor Receptor-1
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Subject Areas on Research
- A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use.
- Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells.
- Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia.
- Alteration in angiogenic and anti-angiogenic forms of vascular endothelial growth factor-A in skeletal muscle of patients with intermittent claudication following exercise training.
- Circulating angiogenic factors and abnormal uterine artery Doppler velocimetry in the second trimester.
- Co-expression of angiogenic markers and associations with prognosis in advanced epithelial ovarian cancer: a Gynecologic Oncology Group study.
- Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport.
- Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
- Differential expression of VEGF isoforms in mouse during development and in the adult.
- Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature.
- Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women.
- First trimester placental growth factor and soluble fms-like tyrosine kinase 1 and risk for preeclampsia.
- Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids.
- Functional FLT1 Genetic Variation is a Prognostic Factor for Recurrence in Stage I-III Non-Small-Cell Lung Cancer.
- Hypoxic Gene Expression of Donor Bronchi Linked to Airway Complications after Lung Transplantation.
- Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1.
- Independent prognostic relevance of microvessel density in advanced epithelial ovarian cancer and associations between CD31, CD105, p53 status, and angiogenic marker expression: A Gynecologic Oncology Group study.
- Metabolism and vascular fatty acid transport.
- PAX3-FOXO1 fusion gene in rhabdomyosarcoma.
- Phase I study of every 2- or 3-week dosing of ramucirumab, a human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2 in patients with advanced solid tumors.
- Phase III Trial of Adjuvant Sunitinib in Patients with High-Risk Renal Cell Carcinoma: Exploratory Pharmacogenomic Analysis.
- Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer.
- Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance.
- Regulation of flt-1 expression during mouse embryogenesis suggests a role in the establishment of vascular endothelium.
- Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells.
- Relationship of smoking and fibrosis in patients with chronic hepatitis C.
- Relaxin-2 and Soluble Flt1 Levels in Peripartum Cardiomyopathy: Results of the Multicenter IPAC Study.
- Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth.
- The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin.
- The role of angiogenesis in Group 3 medulloblastoma pathogenesis and survival.
- Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways.
- Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt.
- VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model.
- Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide.
- Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Linardic, Corinne Mary, Associate Professor of Pediatrics, Pharmacology & Cancer Biology