Vascular Endothelial Growth Factor Receptor-2
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Subject Areas on Research
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A comparison of antiangiogenic therapies for the prevention of liver metastases.
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Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.
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Aging is not associated with bone marrow-resident progenitor cell depletion.
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An endothelial TLR4-VEGFR2 pathway mediates lung protection against oxidant-induced injury.
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An open-label study to determine the maximum tolerated dose of the multitargeted tyrosine kinase inhibitor CEP-11981 in patients with advanced cancer.
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Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells
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Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators.
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Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.
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Cell-Demanded VEGF Release via Nanocapsules Elicits Different Receptor Activation Dynamics and Enhanced Angiogenesis
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Circulating progenitor cells can be reliably identified on the basis of aldehyde dehydrogenase activity.
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Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations.
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Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
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Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries.
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Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity.
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Direct Evidence of Target Inhibition with Anti-VEGF, EGFR, and mTOR Therapies in a Clinical Model of Wound Healing.
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Effect of pazopanib on tumor microenvironment and liposome delivery.
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Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
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Endoglin interacts with VEGFR2 to promote angiogenesis.
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From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?
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Hypoxic Gene Expression of Donor Bronchi Linked to Airway Complications after Lung Transplantation.
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IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.
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Immediate and long-term consequences of vascular toxicity during zebrafish development.
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Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium study.
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Late outgrowth endothelial progenitor cells in patients with age-related macular degeneration.
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Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.
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Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding.
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NgBR is essential for endothelial cell glycosylation and vascular development.
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Pharmacodynamic analysis of target inhibition and endothelial cell death in tumors treated with the vascular endothelial growth factor receptor antagonists SU5416 or SU6668.
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Phase I study of every 2- or 3-week dosing of ramucirumab, a human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2 in patients with advanced solid tumors.
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Phase I/II trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice-weekly methotrexate, and daily prednisone as therapy for metastatic breast cancer using vascular endothelial growth factor and soluble vascular endothelial growth factor receptor levels as markers of response.
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Phase III Trial of Adjuvant Sunitinib in Patients with High-Risk Renal Cell Carcinoma: Exploratory Pharmacogenomic Analysis.
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Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor.
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Reduction of Stat3 activity attenuates HIV-induced kidney injury.
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Regional effects of an antivascular endothelial growth factor receptor monoclonal antibody on receptor phosphorylation and apoptosis in human 253J B-V bladder cancer xenografts.
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Regulation of blood vessel versus lymphatic vessel growth in the cornea.
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Relationship of smoking and fibrosis in patients with chronic hepatitis C.
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Selective coexpression of VEGF receptor 2 in EGFRvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature.
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Synergistic induction of mitogen-activated protein kinase phosphatase-1 by thrombin and epidermal growth factor requires vascular endothelial growth factor receptor-2.
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Synergy between tumor immunotherapy and antiangiogenic therapy.
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Targeted inhibition of VEGF receptor 2: an update on ramucirumab.
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Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer.
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Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.
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The Flk1-myr::mCherry mouse as a useful reporter to characterize multiple aspects of ocular blood vessel development and disease.
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The effect of vascular endothelial growth factor (VEGF) presentation within fibrin matrices on endothelial cell branching
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The effects of ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in mice.
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The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF
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Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level.
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Tumor vascular permeability to a nanoprobe correlates to tumor-specific expression levels of angiogenic markers.
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VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model.
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VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF
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Vascular endothelial growth factor induces abnormal microvasculature in the endoglin heterozygous mouse brain.
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Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression.
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Vascular-targeted photothermal therapy of an orthotopic murine glioma model.