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Subject Areas on Research
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3D phenotyping and quantitative trait locus mapping identify core regions of the rice genome controlling root architecture.
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A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck.
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
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A Segregating Inversion Generates Fitness Variation in Yellow Monkeyflower (Mimulus guttatus).
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A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.
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A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease.
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A cytonuclear incompatibility causes anther sterility in Mimulus hybrids.
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A gain-of-function polymorphism controlling complex traits and fitness in nature.
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A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor.
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A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes.
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A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic.
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A global reference for human genetic variation.
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A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke.
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A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.
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A novel genetic locus modulates infarct volume independently of the extent of collateral circulation.
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A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
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A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia.
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A simple genetic incompatibility causes hybrid male sterility in mimulus.
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A simple method for computing exact probabilities of mutation numbers.
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A spontaneous deletion within the desmoglein 3 extracellular domain of mice results in hypomorphic protein expression, immunodeficiency, and a wasting disease phenotype.
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Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.
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Adjusting for covariates on a slippery slope: linkage analysis of change over time.
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Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of Alzheimer's disease-associated genetic variants.
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Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
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An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome.
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An international collaborative family-based whole genome quantitative trait linkage scan for myopic refractive error.
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An international collaborative family-based whole-genome linkage scan for high-grade myopia.
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Analysis of ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in ALDH1A2.
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Antagonistic selection and pleiotropy constrain the evolution of plant chemical defenses.
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Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis.
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Applications of a rat multiple tissue gene expression data set.
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Assessment of gene-by-sex interaction effect on bone mineral density.
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Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
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Association of Forced Vital Capacity with the Developmental Gene NCOR2.
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Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort.
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Association test for X-linked QTL in family-based designs.
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Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs.
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Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk.
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Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population.
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Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.
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Beyond QTL cloning.
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Broad regulation of gene isoform expression by Wnt signaling in cancer.
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Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.
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Can the Environment have a Genetic Basis? A Case Study of Seedling Establishment in Arabidopsis thaliana.
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Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans.
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Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice.
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Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation.
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Characterizing genetic and environmental influences on variable DNA methylation using monozygotic and dizygotic twins.
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Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.
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Collagen-related genes influence the glaucoma risk factor, central corneal thickness.
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Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.
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Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.
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Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.
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Complex genetic interactions in a quantitative trait locus.
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Complex-trait analysis in plants.
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Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.
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Comprehensive functional genomic resource and integrative model for the human brain.
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Connecting genetic risk to disease end points through the human blood plasma proteome.
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Contribution of chromosomal polymorphisms to the G-matrix of Mimulus guttatus.
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CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
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Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers.
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Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
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Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer.
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DIACYLGLYCEROL ACYLTRANSFERASE1 Contributes to Freezing Tolerance.
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DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.
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DNase I sensitivity QTLs are a major determinant of human expression variation.
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Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.
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Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.
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Dissecting the regulatory architecture of gene expression QTLs.
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Dissecting the role of a large chromosomal inversion in life history divergence throughout the Mimulus guttatus species complex.
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Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction.
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Ecological genomics of Boechera stricta: identification of a QTL controlling the allocation of methionine- vs branched-chain amino acid-derived glucosinolates and levels of insect herbivory.
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Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes.
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Effects of covariates: a summary of Group 5 contributions.
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Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.
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EndoU is a novel regulator of AICD during peripheral B cell selection.
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Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults.
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Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
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Epistasis among Drosophila persimilis factors conferring hybrid male sterility with D. pseudoobscura bogotana.
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Epistasis and balanced polymorphism influencing complex trait variation.
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Epistasis modifies the dominance of loci causing hybrid male sterility in the Drosophila pseudoobscura species group.
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Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen.
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Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.
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Evolutionary dynamics of an Arabidopsis insect resistance quantitative trait locus.
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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.
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Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci.
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Exploiting expression patterns across multiple tissues to map expression quantitative trait loci.
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Expression quantitative trait locus analysis identifies novel genes for statin myopathy.
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Failure to replicate two mate preference QTLs across multiple strains of Drosophila pseudoobscura.
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Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus.
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Five anthocyanin polymorphisms are associated with an R2R3-MYB cluster in Mimulus guttatus (Phrymaceae).
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From genotype to phenotype: systems biology meets natural variation.
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From lab to field, new approaches to phenotyping root system architecture.
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Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death.
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Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice.
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GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
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Gene-trait similarity regression for multimarker-based association analysis.
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Generalized admixture mapping for complex traits.
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Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model.
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Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.
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Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome.
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
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Genetic analysis of susceptibility to Chlamydia trachomatis in mouse.
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Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium.
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Genetic and physiological basis of adaptive salt tolerance divergence between coastal and inland Mimulus guttatus.
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Genetic architecture and adaptation of flowering time among environments.
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Genetic architecture of divergence: the selfing syndrome in Ipomoea lacunosa.
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Genetic architecture of gene expression traits across diverse populations.
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Genetic architecture of plastic methyl jasmonate responses in Arabidopsis thaliana.
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Genetic architecture of quantitative flower and leaf traits in a pair of sympatric sister species of Primulina.
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Genetic divergence causes parallel evolution of flower color in Chilean Mimulus.
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Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.
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Genetic studies of body mass index yield new insights for obesity biology.
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Genetic trade-offs and conditional neutrality contribute to local adaptation.
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Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival.
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Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival.
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Genetic variants in RUNX3, AMD1 and MSRA in the methionine metabolic pathway and survival in nonsmall cell lung cancer patients.
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Genetic variants in nucleotide excision repair pathway predict survival of esophageal squamous cell cancer patients receiving platinum-based chemotherapy.
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Genetic variants in the PIWI-piRNA pathway gene DCP1A predict melanoma disease-specific survival.
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Genetic variants in the calcium signaling pathway genes are associated with cutaneous melanoma-specific survival.
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Genetic variants in the human leukocyte antigen region and survival of Chinese patients with non-small cell lung carcinoma.
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Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk.
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Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk.
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Genetic variants of CHEK1, PRIM2 and CDK6 in the mitotic phase-related pathway are associated with nonsmall cell lung cancer survival.
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Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study.
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Genetic variants of the peroxisome proliferator-activated receptor (PPAR) signaling pathway genes and risk of pancreatic cancer.
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Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice.
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Genetics of drought adaptation in Arabidopsis thaliana II. QTL analysis of a new mapping population, KAS-1 x TSU-1.
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Genetics of hybrid male sterility among strains and species in the Drosophila pseudoobscura species group.
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Genetics of incipient speciation in Drosophila mojavensis. I. Male courtship song, mating success, and genotype x environment interactions.
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Genetics of incipient speciation in Drosophila mojavensis. III. Life-history divergence in allopatry and reproductive isolation.
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Genetics of incipient speciation in Drosophila mojavensis: II. Host plants and mating status influence cuticular hydrocarbon QTL expression and G x E interactions.
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Genetics of superior growth traits in trees are being mapped but will the faster-growing risk-takers make it in the wild?
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Genome sequencing unveils a regulatory landscape of platelet reactivity.
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Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.
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Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality.
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Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.
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Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium.
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Genome-wide analysis identifies 12 loci influencing human reproductive behavior.
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Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus.
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Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels.
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Genome-wide association analysis identifies six new loci associated with forced vital capacity.
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Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.
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Genome-wide association of pericardial fat identifies a unique locus for ectopic fat.
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Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.
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Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
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Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.
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Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference.
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Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
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Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
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Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus.
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Genome-wide association study of obsessive-compulsive disorder.
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Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family.
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Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies.
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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
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Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake.
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Genome-wide significant risk associations for mucinous ovarian carcinoma.
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Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
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Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
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Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.
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Genomic approaches for understanding the genetics of complex disease.
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Gnao1 (G alphaO protein) is a likely genetic contributor to variation in physical dependence on opioids in mice.
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High-throughput imaging and analysis of root system architecture in Brachypodium distachyon under differential nutrient availability.
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Human genetic admixture.
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Hypertension Susceptibility Loci are Associated with Anthracycline-related Cardiotoxicity in Long-term Childhood Cancer Survivors.
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Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus.
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IMAGE: high-powered detection of genetic effects on DNA methylation using integrated methylation QTL mapping and allele-specific analysis.
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Identical twins carry a persistent epigenetic signature of early genome programming.
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Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.
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Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
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Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
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Identification of major quantitative trait loci underlying floral pollination syndrome divergence in Penstemon.
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Identification of novel candidate risk genes for myelomeningocele within the glucose homeostasis/oxidative stress and folate/one-carbon metabolism networks.
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Identification of quantitative trait loci and a candidate locus for freezing tolerance in controlled and outdoor environments in the overwintering crucifer Boechera stricta.
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Identification of six new susceptibility loci for invasive epithelial ovarian cancer.
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Identifying human disease genes through cross-species gene mapping of evolutionary conserved processes.
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Imaging and analysis platform for automatic phenotyping and trait ranking of plant root systems.
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Impact of measurement error on testing genetic association with quantitative traits.
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Increased efficiency of case-control association analysis by using allele-sharing and covariate information.
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Indirect evolution of hybrid lethality due to linkage with selected locus in Mimulus guttatus
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Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability.
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Inherited variants in regulatory T cell genes and outcome of ovarian cancer.
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Initial sequencing and comparative analysis of the mouse genome.
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Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.
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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation.
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Interpreting analyses of continuous covariates in affected sibling pair linkage studies.
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Intersection tests for single marker QTL analysis can be more powerful than two marker QTL analysis.
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Intraspecific Genetic Variation for Behavioral Isolation Loci in Drosophila.
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Is local adaptation in Mimulus guttatus caused by trade-offs at individual loci?
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Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.
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Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
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Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
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Large-scale association analysis identifies new risk loci for coronary artery disease.
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Leaf shape evolution has a similar genetic architecture in three edaphic specialists within the Mimulus guttatus species complex.
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Leveraging population information in family-based rare variant association analyses of quantitative traits.
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Life-history QTLS and natural selection on flowering time in Boechera stricta, a perennial relative of Arabidopsis.
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Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.
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Linking short tandem repeat polymorphisms with cytosine modifications in human lymphoblastoid cell lines.
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Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL.
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Major QTL controls adaptation to serpentine soils in Mimulus guttatus.
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Major QTLs for critical photoperiod and vernalization underlie extensive variation in flowering time in the Mimulus guttatus species complex.
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Mapping and characterization of structural variation in 17,795 human genomes.
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Mapping eQTL by leveraging multiple tissues and DNA methylation.
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Mapping of QTL for resistance against the crucifer specialist herbivore Pieris brassicae in a new Arabidopsis inbred line population, Da(1)-12 x Ei-2.
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Mapping of ionomic traits in Mimulus guttatus reveals Mo and Cd QTLs that colocalize with MOT1 homologues.
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Mapping of within-species segregation distortion in Drosophila persimilis and hybrid sterility between D. persimilis and D. pseudoobscura.
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Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.
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Mapping the proteo-genomic convergence of human diseases.
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Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort.
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Meta-analysis identifies common variants associated with body mass index in east Asians.
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Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology.
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Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes.
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Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits.
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Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.
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Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis.
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Minor quantitative trait loci underlie floral traits associated with mating system divergence in Mimulus.
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Modifier genes and heart failure.
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Multi-allelic major effect genes interact with minor effect QTLs to control adaptive color pattern variation in Heliconius erato.
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Multi-ethnic genome-wide association study for atrial fibrillation.
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Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
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Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.
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Multiple quantitative trait loci modify the heart failure phenotype in murine cardiomyopathy.
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Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.
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Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume.
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Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke.
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Natural variation in MAM within and between populations of Arabidopsis lyrata determines glucosinolate phenotype.
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New genetic loci link adipose and insulin biology to body fat distribution.
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
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New locus for autosomal dominant high myopia maps to the long arm of chromosome 17.
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Novel Neuroprotective Loci Modulating Ischemic Stroke Volume in Wild-Derived Inbred Mouse Strains.
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Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer.
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Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer.
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Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits.
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Oxidative stress survival in a clinical Saccharomyces cerevisiae isolate is influenced by a major quantitative trait nucleotide.
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Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction.
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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
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Pleiotropic quantitative trait loci contribute to population divergence in traits associated with life-history variation in Mimulus guttatus.
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Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence.
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Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer.
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Potentially functional genetic variants in PLIN2, SULT2A1 and UGT1A9 genes of the ketone pathway and survival of nonsmall cell lung cancer.
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Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non-small cell lung cancer in the PLCO cancer screening trial.
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Potentially functional genetic variants in the complement-related immunity gene-set are associated with non-small cell lung cancer survival.
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Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients.
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Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
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Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family Study.
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Protein Quantitative Trait Loci Analysis Identifies Genetic Variation in the Innate Immune Regulator TOLLIP in Post-Lung Transplant Primary Graft Dysfunction Risk.
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Protein prediction for trait mapping in diverse populations.
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QTL Mapping in Three Rice Populations Uncovers Major Genomic Regions Associated with African Rice Gall Midge Resistance.
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QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival.
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Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent.
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Quantitative genetic analysis of the retinal vascular caliber: the Australian Twins Eye Study.
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Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association.
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Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes.
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Quantitative trait locus mapping reveals regions of the maize genome controlling root system architecture.
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RNA-Seq optimization with eQTL gold standards.
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Random Forests approach for identifying additive and epistatic single nucleotide polymorphisms associated with residual feed intake in dairy cattle.
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Recombination and gene conversion in a 170-kb genomic region of Arabidopsis thaliana.
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Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure.
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Replicated Landscape Genomics Identifies Evidence of Local Adaptation to Urbanization in Wood Frogs.
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Screening for pain phenotypes: analysis of three congenic mouse strains on a battery of nine nociceptive assays.
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Selection on QTL and complex traits in complex environments.
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Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast.
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Serum lipids in the GENECARD study of coronary artery disease identify quantitative trait loci and phenotypic subsets on chromosomes 3q and 5q.
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Signatures of demography and recombination at coding genes in naturally-distributed populations of Arabidopsis lyrata subsp. petraea.
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Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus.
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Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage.
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Strong selection genome-wide enhances fitness tradeoffs across environments and episodes of selection
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Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs.
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The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits.
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The complex genetics of gait speed: genome-wide meta-analysis approach.
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The earliest stages of adaptation in an experimental plant population: strong selection on QTLs for seed dormancy.
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The ecological, genetic and genomic architecture of local adaptation and population differentiation in Boechera stricta
.
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The evolution of quantitative traits in complex environments
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The evolutionary significance of cis-regulatory mutations.
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The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus.
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The genetic architecture and evolution of life-history divergence among perennials in the Mimulus guttatus
species complex.
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The genetic architecture of biofilm formation in a clinical isolate of Saccharomyces cerevisiae.
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The genetic architecture of gene expression levels in wild baboons.
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The genetic architecture of local adaptation and reproductive isolation in sympatry within the Mimulus guttatus species complex.
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The genetic basis of developmental abnormalities in interpopulation hybrids of the moss Ceratodon purpureus.
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The genetics of speciation by reinforcement.
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The relationship between retinal arteriolar and venular calibers is genetically mediated, and each is associated with risk of cardiovascular disease.
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The statistics of bulk segregant analysis using next generation sequencing.
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Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk.
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Tissue-specific genetic control of splicing: implications for the study of complex traits.
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Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.
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Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma.
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Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations.
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Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights.
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Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource.
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Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.
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Twins eye study in Tasmania (TEST): rationale and methodology to recruit and examine twins.
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Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.
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Understanding rice adaptation to varying agro-ecosystems: trait interactions and quantitative trait loci.
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Unifying genetic canalization, genetic constraint, and genotype-by-environment interaction: QTL by genomic background by environment interaction of flowering time in Boechera stricta.
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Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.
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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer.
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Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.
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Variation in recombination rate may bias human genetic disease mapping studies.
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Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation.
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Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function.
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What can patterns of differentiation across plant genomes tell us about adaptation and speciation?
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Which evolutionary processes influence natural genetic variation for phenotypic traits?
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Wnt-regulated lncRNA discovery enhanced by in vivo identification and CRISPRi functional validation.
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rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology.
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Keywords of People
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Immunology
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Li, Yi-Ju,
Professor of Biostatistics & Bioinformatics,
Biostatistics & Bioinformatics
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Magwene, Paul Mitaari,
Professor of Biology,
Biology
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Mitchell-Olds, Thomas,
Newman Ivey White Distinguished Professor of Biology,
Biology
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Pitt, Geoffrey Stuart,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
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Wray, Gregory Allan,
Professor of Biology,
Evolutionary Anthropology