Chromosomes, Human, Y

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  Subject Areas on Research

  • A family of human Y chromosomes has dispersed throughout northern Eurasia despite a 1.8-Mb deletion in the azoospermia factor c region. 
  • A haplotype map of the human genome. 
  • AZFc deletions and spermatogenic failure: a population-based survey of 20,000 Y chromosomes. 
  • Absence of Y chromosome in human placental site trophoblastic tumor. 
  • Abundant gene conversion between arms of palindromes in human and ape Y chromosomes. 
  • Ancient West African foragers in the context of African population history. 
  • Are sequence family variants useful for identifying deletions in the human Y chromosome? 
  • Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content. 
  • Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee. 
  • De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay. 
  • Diverse patterns of T-cell response against multiple newly identified human Y chromosome-encoded minor histocompatibility epitopes. 
  • Genomics and genetics of human and primate y chromosomes. 
  • Has the chimpanzee Y chromosome been sequenced? 
  • High mutation rates have driven extensive structural polymorphism among human Y chromosomes. 
  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. 
  • Maternal microchimerism in Hirschsprung's disease. 
  • Polymorphism for a 1.6-Mb deletion of the human Y chromosome persists through balance between recurrent mutation and haploid selection. 
  • Post-Austronesian migrational wave of West Polynesians to Micronesia. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Should Y stay or should Y go: the evolution of non-recombining sex chromosomes. 
  • Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes. 
  • The DNA sequence of the human X chromosome. 
  • The generation of extracellular DNA in SLE: the role of death and sex. 
  • The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. 
  • Unmasking a role for sex chromosomes in gene silencing. 
  • Y chromosome gr/gr deletions are a risk factor for low semen quality.