Gastrointestinal Tract

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  Subject Areas on Research

  • A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology. 
  • A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy. 
  • A phase II study of external beam radiotherapy combined with permanent source brachytherapy for intermediate-risk, clinically localized adenocarcinoma of the prostate: preliminary results of RTOG P-0019. 
  • A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors. 
  • A role for gut microbiota in host niche differentiation. 
  • Accelerated cell cycles enable organ regeneration under developmental time constraints in the Drosophila hindgut. 
  • Access to technology to support telehealth in areas without specialty care for liver disease. 
  • Acoustic radiation force impulse (ARFI) imaging of the gastrointestinal tract. 
  • Acute gastrointestinal vaso-occlusive ischemia in sickle cell disease: CT imaging features and clinical outcome. 
  • Adaptation in a mouse colony monoassociated with Escherichia coli K-12 for more than 1,000 days. 
  • American Gastroenterological Association Membership Policy Priorities: Building the American Gastroenterological Association Advocacy Agenda. 
  • An Impetus for Change: How COVID-19 Will Transform the Delivery of GI Health Care. 
  • Anatomy and physiology of the luminal gut: enteral access implications. 
  • Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease. 
  • Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. 
  • Assessing adverse events of postprostatectomy radiation therapy for prostate cancer: evaluation of outcomes in the Regione Emilia-Romagna, Italy. 
  • Associations Between Nutrition, Gut Microbiome, and Health in A Novel Nonhuman Primate Model. 
  • Autologous gastrointestinal reconstruction: review of the optimal nontransplant surgical options for adults and children with short bowel syndrome. 
  • Baby, It's Cold Outside: Host-Microbiota Relationships Drive Temperature Adaptations. 
  • Beyond bacteria: a study of the enteric microbial consortium in extremely low birth weight infants. 
  • Blocking Cyclin-Dependent Kinase 4/6 During Single Dose Versus Fractionated Radiation Therapy Leads to Opposite Effects on Acute Gastrointestinal Toxicity in Mice. 
  • Captivity humanizes the primate microbiome. 
  • Chimpanzees and humans harbour compositionally similar gut enterotypes. 
  • Clinical Implementation of Dual-Energy CT for Gastrointestinal Imaging. 
  • Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder. 
  • Colonization With Levofloxacin-resistant Extended-spectrum β-Lactamase-producing Enterobacteriaceae and Risk of Bacteremia in Hematopoietic Stem Cell Transplant Recipients. 
  • Comparative Developmental Transcriptomics Reveals Rewiring of a Highly Conserved Gene Regulatory Network during a Major Life History Switch in the Sea Urchin Genus Heliocidaris. 
  • Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. 
  • Cse1l is a negative regulator of CFTR-dependent fluid secretion. 
  • Detection of Kawasaki disease-associated antigen in inflamed gastrointestinal tract in acute Kawasaki disease. 
  • Development, diet and dynamism: longitudinal and cross-sectional predictors of gut microbial communities in wild baboons. 
  • Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management. 
  • Diet rapidly and reproducibly alters the human gut microbiome. 
  • Dissecting the in vivo metabolic potential of two human gut acetogens. 
  • Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. 
  • Dynamic linear models guide design and analysis of microbiota studies within artificial human guts. 
  • Early outcomes of empiric embolization of tumor-related gastrointestinal hemorrhage in patients with advanced malignancy. 
  • Effect of glycemia on plasma incretins and the incretin effect during oral glucose tolerance test. 
  • Effects of electroacupuncture on gastric motility and heart rate variability in conscious rats. 
  • Electrical stimulation of gut motility guided by an in silico model. 
  • Endoscopic management of gastrointestinal bleeding from multifocal lymphangioendotheliomatosis with thrombocytopenia: limited efficacy and complications. 
  • Enteric microbiome metabolites correlate with response to simvastatin treatment. 
  • Enterovirus Replication and Dissemination Are Differentially Controlled by Type I and III Interferons in the Gastrointestinal Tract. 
  • Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection. 
  • Evidence for a core gut microbiota in the zebrafish. 
  • Expanding the phenotype of multifocal lymphangioendotheliomatosis with thrombocytopenia. 
  • Factors associated with the diversification of the gut microbial communities within chimpanzees from Gombe National Park. 
  • Feeding strategy shapes gut metagenomic enrichment and functional specialization in captive lemurs. 
  • From esophagus to rectum: a comprehensive review of alimentary tract perforations at computed tomography. 
  • Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques. 
  • GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome. 
  • Gastrointestinal hormones and the gut connectome. 
  • Gastrointestinal microbiota alteration induced by Mucor circinelloides in a murine model. 
  • Genetic and phenotypic characterization of indolent T-cell lymphoproliferative disorders of the gastrointestinal tract. 
  • Genomic erosion and extensive horizontal gene transfer in gut-associated Acetobacteraceae. 
  • Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe. 
  • Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. 
  • Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE₂. 
  • Gut microbial succession follows acute secretory diarrhea in humans. 
  • Gut microbiota from twins discordant for obesity modulate metabolism in mice. 
  • Gut organoids: mini-tissues in culture to study intestinal physiology and disease. 
  • Gut-immune-brain dysfunction in Autism: Importance of sex. 
  • Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish. 
  • Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. 
  • Image-guided percutaneous drainage vs. surgical repair of gastrointestinal anastomotic leaks: is there a difference in hospital course or hospitalization cost? 
  • Immune modulator-induced changes in the gastrointestinal tract - reply. 
  • Increased prevalence of eosinophilic gastrointestinal disorders in pediatric PTEN hamartoma tumor syndromes. 
  • Influence of the Gastrointestinal Environment on the Bioavailability of Ethinyl Estradiol Sorbed to Single-Walled Carbon Nanotubes. 
  • Interactions of Gut Endocrine Cells with Epithelium and Neurons. 
  • Intersection of salt- and immune-mediated mechanisms of hypertension in the gut microbiome. 
  • Intestinal Acute Graft-versus-Host Disease: A Bug Highway to the Bloodstream. 
  • Intestinal microbiota composition in fishes is influenced by host ecology and environment. 
  • Long-term results of an RTOG Phase II trial (00-19) of external-beam radiation therapy combined with permanent source brachytherapy for intermediate-risk clinically localized adenocarcinoma of the prostate. 
  • MR Imaging Evaluation of Inflammatory Bowel Disease in Children:: Where Are We Now in 2019. 
  • Mammalian intestinal allometry, phylogeny, trophic level and climate. 
  • Management and outcomes of gastrointestinal congenital anomalies in low, middle and high income countries: protocol for a multicentre, international, prospective cohort study. 
  • Manipulating the gut microbiome to decrease uremic toxins. 
  • Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation. 
  • Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir. 
  • Microbial influences on gut development and gut-brain communication. 
  • Microbiome reduction and endosymbiont gain from a switch in sea urchin life history. 
  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study. 
  • NK cell recruitment limits tissue damage during an enteric helminth infection. 
  • Nutrition and gastrointestinal tract assessment and management of children with dysphagia. 
  • Ontogenetic Differences in Dietary Fat Influence Microbiota Assembly in the Zebrafish Gut. 
  • Overcoming disparities for sexual and gender minority patients and providers in gastroenterology and hepatology: introduction to Rainbows in Gastro. 
  • Parkinson's disease from the gut. 
  • Patterns and scales in gastrointestinal microbial ecology. 
  • Patterns of gut bacterial colonization in three primate species. 
  • Personalized Radiation Attenuating Materials for Gastrointestinal Mucosal Protection. 
  • Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology. 
  • Plasma cells are essentially absent in the luminal gastrointestinal tract of patients with "complete" 22q11.2 deletion syndrome (DiGeorge syndrome). 
  • Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants. 
  • Postoperative Radiation Therapy for Prostate Cancer: Comparison of Conventional Versus Hypofractionated Radiation Regimens. 
  • Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions. 
  • Progressive lentivirus infection induces natural killer cell receptor-expressing B cells in the gastrointestinal tract. 
  • Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice. 
  • RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. 
  • Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. 
  • Reflectance spectroscopy. 
  • Regulation of CD8(+) T cell functions by RARgamma. 
  • SIV-induced instability of the chimpanzee gut microbiome. 
  • SUMOylation Connects Cell Stress Responses and Inflammatory Control: Lessons From the Gut as a Model Organ. 
  • Safety of bevacizumab in patients with metastatic breast cancer. 
  • Selective decontamination of digestive tract in intensive care. 
  • Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. 
  • Single continuous lumen formation in the zebrafish gut is mediated by smoothened-dependent tissue remodeling. 
  • Social behavior shapes the chimpanzee pan-microbiome 
  • Society of abdominal radiology gastrointestinal bleeding disease-focused panel consensus recommendations for CTA technical parameters in the evaluation of acute overt gastrointestinal bleeding. 
  • Special issue: gut microbial communities in health and disease. 
  • Stem Cell-Derived Models of Viral Infections in the Gastrointestinal Tract. 
  • The Diagnostic Yield of Site and Symptom-Based Biopsies for Acute Gastrointestinal Graft-Versus-Host Disease: A 5-Year Retrospective Review. 
  • The MAL-ED study: a multinational and multidisciplinary approach to understand the relationship between enteric pathogens, malnutrition, gut physiology, physical growth, cognitive development, and immune responses in infants and children up to 2 years of age in resource-poor environments. 
  • The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice. 
  • The distinct binding specificities exhibited by enterobacterial type 1 fimbriae are determined by their fimbrial shafts. 
  • The gut connectome: making sense of what you eat. 
  • The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. 
  • The now and then of gut-brain signaling. 
  • The stepwise assembly of the neonatal virome is modulated by breastfeeding. 
  • Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity. 
  • Type III Interferons in Antiviral Defenses at Barrier Surfaces. 
  • Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock. 
  • What if gut hormones aren't really hormones: DPP-4 inhibition and local action of GLP-1 in the gastrointestinal tract. 
  • Where the gut meets the brain. 
  • Widespread organ tolerance to Xist loss and X reactivation except under chronic stress in the gut. 
  • mTOR is critical for intestinal T-cell homeostasis and resistance to Citrobacter rodentium. 
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  Keywords of People

  • Hyslop, Terry, Adjunct Professor in the Department of Biostatistics & Bioinformatics, Duke Cancer Institute
  • Kim, Charles Yoon, Professor of Radiology, Radiology, Interventional Radiology