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Subject Areas on Research
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3-Dimensional spatially organized PEG-based hydrogels for an aortic valve co-culture model.
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A 3D Poly(ethylene glycol)-based Tumor Angiogenesis Model to Study the Influence of Vascular Cells on Lung Tumor Cell Behavior.
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A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer.
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A comparison of antiangiogenic therapies for the prevention of liver metastases.
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A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.
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A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR.
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A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity.
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A flow cytometric crossmatch test using endothelial precursor cells isolated from peripheral blood.
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A macrophage-endothelial immunoregulatory axis ameliorates septic acute kidney injury.
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A model of giant vacuole dynamics in human Schlemm's canal endothelial cells.
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A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke.
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A new generation organ culture arising from cross-talk between multiple primary human cell types.
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A novel monoclonal antibody to secreted frizzled-related protein 2 inhibits tumor growth.
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A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
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A novel somatic mutation in GNAQ in a capillary malformation provides insight into molecular pathogenesis.
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A nuclear factor-kappaB inhibitor BAY11-7082 inhibits interactions between human endothelial cells, T cells, and monocytes.
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A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated Tie2 activation and function.
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A practical model for economic evaluation of tissue-engineered therapies.
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A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model.
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A systems biology model of junctional localization and downstream signaling of the Ang-Tie signaling pathway.
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A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation.
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ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.
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ADAM12: a genetic modifier of preclinical peripheral arterial disease.
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ALK1 regulates the internalization of endoglin and the type III TGF-β receptor.
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ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression.
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ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration.
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APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2.
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ATTRACT.
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Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.
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Adhesion and function of human endothelial cells co-cultured on smooth muscle cells.
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Adhesion molecules and hydroxyurea in the pathophysiology of sickle cell disease.
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Advanced glycation end-product of low density lipoprotein activates the toll-like 4 receptor pathway implications for diabetic atherosclerosis.
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Aldehyde dehydrogenase activity allows reliable EPC enumeration in stored peripheral blood samples.
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Alterations in human trabecular meshwork cell homeostasis by selenium.
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Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma.
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An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.
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An In Vitro Bovine Cellular Model for Human Schlemm's Canal Endothelial Cells and Their Response to TGFβ Treatment.
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An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation.
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An active learning approach for rapid characterization of endothelial cells in human tumors.
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An open-label study to determine the maximum tolerated dose of the multitargeted tyrosine kinase inhibitor CEP-11981 in patients with advanced cancer.
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Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells
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Angiopoietin-2 confers Atheroprotection in apoE-/- mice by inhibiting LDL oxidation via nitric oxide.
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Angiostatin directly inhibits human prostate tumor cell invasion by blocking plasminogen binding to its cellular receptor, CD26.
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Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase.
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Antagonism Between PEDF and TGF-β Contributes to Type VI Osteogenesis Imperfecta Bone and Vascular Pathogenesis.
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Antagonists of the system L neutral amino acid transporter (LAT) promote endothelial adhesivity of human red blood cells.
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Anti-Angiotensin II Type 1 Receptor and Anti-Endothelial Cell Antibodies: A Cross-Sectional Analysis of Pathological Findings in Allograft Biopsies.
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Anti-inflammatory and vasoprotective activity of a retroviral-derived peptide, homologous to human endogenous retroviruses: endothelial cell effects.
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Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase.
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Anti-inflammatory signaling during ex vivo liver perfusion improves the preservation of pig liver grafts before transplantation.
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Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model.
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Antiangiogenic treatment with three thrombospondin-1 type 1 repeats versus gemcitabine in an orthotopic human pancreatic cancer model.
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Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management.
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Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation.
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Application of a Novel Murine Ear Vein Model to Evaluate the Effects of a Vascular Radioprotectant on Radiation-Induced Vascular Permeability and Leukocyte Adhesion.
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Association of serial biochemical markers with acute ischemic stroke: the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator Stroke Study.
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Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium.
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Autologous endothelial progenitor cell-seeding technology and biocompatibility testing for cardiovascular devices in large animal model.
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Basolateral amygdala volume and cell numbers in major depressive disorder: a postmortem stereological study.
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Benzo(a)pyrene inhibits expression of inducible heat shock protein 70 in vascular endothelial cells.
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Beyond angiogenesis: the role of endothelium in the bone marrow vascular niche.
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Bioengineered human acellular vessels recellularize and evolve into living blood vessels after human implantation.
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Biology of cerebral arteriovenous malformations with a focus on inflammation.
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Biomechanical effects of flow and coculture on human aortic and cord blood-derived endothelial cells.
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Biomechanical strain as a trigger for pore formation in Schlemm's canal endothelial cells.
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Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction.
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Biomimetic Hydrogels with Immobilized EphrinA1 for Therapeutic Angiogenesis
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Biomimetic hydrogels with pro-angiogenic properties.
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Blockade of tissue factor-factor X binding attenuates sepsis-induced respiratory and renal failure.
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Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis.
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Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.
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Bombesin-like peptides modulate alveolarization and angiogenesis in bronchopulmonary dysplasia.
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CD44+/CD24- breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties.
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COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.
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Calcineurin is essential for Candida albicans survival in serum and virulence.
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Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.
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Captopril suppresses post-transplantation angiogenic activity in rat allograft coronary vessels.
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Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.
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Caveolar and non-Caveolar Caveolin-1 in ocular homeostasis and disease.
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Cell Line Authentication in Vision Research and Beyond: A Tale Retold.
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Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities.
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Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.
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Cellular adhesion and the endothelium: E-selectin, L-selectin, and pan-selectin inhibitors.
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Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies.
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Cerebral Cavernous Malformations Develop Through Clonal Expansion of Mutant Endothelial Cells.
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Characterization of umbilical cord blood-derived late outgrowth endothelial progenitor cells exposed to laminar shear stress.
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Chemically Orthogonal Protein Ligation Domains for Independent Control of Hydrogel Modification with Adhesive Ligands and Growth Factors.
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Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform.
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Chronic Thromboembolic Pulmonary Hypertension: the Bench.
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Cilia proteins are biomarkers of altered flow in the vasculature.
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Ciliogenesis mechanisms mediated by PAK2-ARL13B signaling in brain endothelial cells is responsible for vascular stability.
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Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin.
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Clinical relevance and IgG subclass determination of non-HLA antibodies identified using endothelial cell precursors isolated from donor blood.
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Cloning and expression of a novel, truncated, progesterone receptor.
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Co-assembling peptides as defined matrices for endothelial cells.
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Combinatorial phenotypic signatures distinguish persistent from resolving methicillin-resistant Staphylococcus aureus bacteremia isolates.
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Combined PI3K/Akt and Smad2 Activation Promotes Corneal Endothelial Cell Proliferation.
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Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations.
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Communication from the Scientific Standardization Committees of the International Society on Thrombosis and Haemostasis on vascular endothelium-related biomarkers in disseminated intravascular coagulation.
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Comparative RNAi screening reveals host factors involved in enterovirus infection of polarized endothelial monolayers.
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Comparative analysis of circulating endothelial progenitor cells in age-related macular degeneration patients using automated rare cell analysis (ARCA) and fluorescence activated cell sorting (FACS).
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Comparison of endothelial cell phenotypic markers of late-outgrowth endothelial progenitor cells isolated from patients with coronary artery disease and healthy volunteers.
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Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro.
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Coupled myovascular expansion directs cardiac growth and regeneration.
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Covalently immobilized platelet-derived growth factor-BB promotes angiogenesis in biomimetic poly(ethylene glycol) hydrogels.
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Covalently-immobilized vascular endothelial growth factor promotes endothelial cell tubulogenesis in poly(ethylene glycol) diacrylate hydrogels.
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Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier.
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Current insights on the biology and clinical aspects of VEGF regulation.
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Cutaneous endothelial cell activation in normal skin of patients with dermatitis herpetiformis associated with increased serum levels of IL-8, sE-Selectin, and TNF-alpha.
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Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries.
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Dabigatran abrogates brain endothelial cell permeability in response to thrombin.
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Decellularized tissue-engineered blood vessel as an arterial conduit.
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Decreased endothelial nitric oxide bioavailability, impaired microvascular function, and increased tissue oxygen consumption in children with falciparum malaria.
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Defibrotide sodium for the treatment of hepatic veno-occlusive disease/sinusoidal obstruction syndrome.
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Degradation of endothelial glycocalyx in Tanzanian children with falciparum malaria.
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Deletion of Atm in Tumor but not Endothelial Cells Improves Radiation Response in a Primary Mouse Model of Lung Adenocarcinoma.
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Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
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Derangement of the endothelial glycocalyx in sepsis.
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Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing.
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Development of a YIGSR-peptide-modified polyurethaneurea to enhance endothelialization.
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Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms.
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Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.
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Differential DNA methylation patterns in human Schlemm's canal endothelial cells with glaucoma.
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Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity.
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Differentiation and characterization of human iPSC-derived vascular endothelial cells under physiological shear stress.
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Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation.
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Directed cell migration on fibronectin gradients: effect of gradient slope.
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Disrupting the vicious cycle created by NOX activation in sickle erythrocytes exposed to hypoxia/reoxygenation prevents adhesion and vasoocclusion.
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Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs.
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Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.
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Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia.
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Dynamic adhesion of umbilical cord blood endothelial progenitor cells under laminar shear stress.
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Dynamic seeding of perfusing human umbilical vein endothelial cells (HUVECs) onto dual-function cell adhesion ligands: Arg-Gly-Asp (RGD)-streptavidin and biotinylated fibronectin.
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EPC mobilization after erythropoietin treatment in acute ST-elevation myocardial infarction: the REVEAL EPC substudy.
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Early Endothelial Activation Precedes Glycocalyx Degradation and Microvascular Dysfunction in Experimentally Induced Plasmodium falciparum and Plasmodium vivax Infection.
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Early detection of cerebrovascular pathology and protective antiviral immunity by MRI.
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Early-outgrowth of endothelial progenitor cells can function as antigen-presenting cells.
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Effect of lipopolysaccharide administration on the number, phenotype and content of nuclear molecules in blood microparticles of normal human subjects.
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Effect of propranolol as antiadhesive therapy in sickle cell disease.
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Effect of streptavidin RGD mutant on the adhesion of endothelial cells.
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Effects of plasminogen activator inhibitor-1-specific RNA aptamers on cell adhesion, motility, and tube formation.
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Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study.
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Electron microscopy of SARS-CoV-2: a challenging task.
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Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function.
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Elevated PTH induces endothelial-to-chondrogenic transition in aortic endothelial cells.
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Elucidating the role of plexin D1 in body fat distribution and susceptibility to metabolic disease using a zebrafish model system.
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Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis.
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Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading.
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Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells.
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Endoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPC.
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Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury.
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Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation.
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Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches.
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Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone.
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Endothelial cell antibodies associated with novel targets and increased rejection.
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Endothelial cell function and endothelial-related disorders following haematopoietic cell transplantation.
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Endothelial colony forming cells (ECFCs) as a model for studying effects of low-dose ionizing radiation: growth inhibition by a single dose.
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Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.
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Endothelial microparticle levels are similar in acute ischemic stroke and stroke mimics due to activation and not apoptosis/necrosis.
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Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo.
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Endothelial progenitor cell therapy for atherosclerosis: the philosopher's stone for an aging population?
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Endothelial progenitor cells: markers of vascular reparative capacity.
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Endothelialization of microporous YIGSR/PEG-modified polyurethaneurea.
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Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.
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Endothelium-targeted gene and cell-based therapies for cardiovascular disease.
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Enhanced inhibition of neointimal hyperplasia by genetically engineered endothelial progenitor cells.
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Enhanced therapeutic neovascularization by CD31-expressing cells and embryonic stem cell-derived endothelial cells engineered with chitosan hydrogel containing VEGF-releasing microtubes
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Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia.
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Enzyme-Responsive Delivery of Multiple Proteins with Spatiotemporal Control
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Erythrocyte-Derived Microparticles Activate Pulmonary Endothelial Cells in a Murine Model of Transfusion.
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Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium.
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Estrogen up-regulates cyclooxygenase-2 via estrogen receptor in human uterine microvascular endothelial cells.
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Evaluation of late outgrowth endothelial progenitor cell and umbilical vein endothelial cell responses to thromboresistant collagen-mimetic hydrogels.
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Evidence for the role of cell stiffness in modulation of volume-regulated anion channels.
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Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone.
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Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans.
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Exosome-eluting stents for vascular healing after ischaemic injury.
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Exploring a peptidomimetic approach of N-cadherin in modulating fibroblast growth factor receptor signaling for corneal endothelial regeneration.
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Expression Profiling of Human Schlemm's Canal Endothelial Cells From Eyes With and Without Glaucoma.
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Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation.
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Extracellular vesicles in atrial fibrillation and stroke.
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Fibronectin Extra Domain A Promotes Liver Sinusoid Repair following Hepatectomy.
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Fibrotic Changes to Schlemm's Canal Endothelial Cells in Glaucoma.
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Flow and high affinity binding affect the elastic modulus of the nucleus, cell body and the stress fibers of endothelial cells.
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Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis
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Formin-like 1 mediates effector T cell trafficking to inflammatory sites to enable T cell-mediated autoimmunity.
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Four-dimensional analysis of vascularization during primary development of an organ, the gonad.
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Frequency-dependent response of the vascular endothelium to pulsatile shear stress.
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From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?
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Functional imaging in bulk tissue specimens using optical emission tomography: fluorescence preservation during optical clearing.
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Fusobacterium nucleatum induces premature and term stillbirths in pregnant mice: implication of oral bacteria in preterm birth.
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G-Protein-Coupled Receptors in Heart Disease.
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Gene expression programs of human smooth muscle cells: tissue-specific differentiation and prognostic significance in breast cancers.
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Gene therapy in tissue-engineered blood vessels.
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Generation of specialized blood vessels via lymphatic transdifferentiation.
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Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction.
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Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium.
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Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.
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Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS).
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Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.
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Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.
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Glycan binding avidity determines the systemic fate of adeno-associated virus type 9.
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Graft-extrinsic cells predominate in vein graft arterialization.
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Gαq and hyper-phosphorylated ERK expression in Sturge-Weber syndrome leptomeningeal blood vessel endothelial cells.
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Haptotactic gradients for directed cell migration: stimulation and inhibition using soluble factors.
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Harnessing Macrophages for Vascularization in Tissue Engineering.
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Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation.
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Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism.
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High-throughput screening for modulators of cellular contractile force.
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Human platelets express endothelial protein C receptor, which can be utilized to enhance localization of factor VIIa activity.
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Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.
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Human umbilical cord blood endothelial progenitor cells decrease vein graft neointimal hyperplasia in SCID mice.
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Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis.
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Hypotrichosis-lymphedema-telangiectasia syndrome: Report of ileal atresia associated with a SOX18 de novo pathogenic variant and review of the phenotypic spectrum.
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Hypoxia-induced blood-brain barrier dysfunction is prevented by pericyte-conditioned media via attenuated actomyosin contractility and claudin-5 stabilization.
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ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration.
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IFI16-STING-NF-κB signaling controls exogenous mitochondrion-induced endothelial activation.
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IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.
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Identification of genes from the fungal pathogen Cryptococcus neoformans related to transmigration into the central nervous system.
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Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension.
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Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis.
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Impaired adenosine-5'-triphosphate release from red blood cells promotes their adhesion to endothelial cells: a mechanism of hypoxemia after transfusion.
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Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin.
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Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.
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Improved Angiogenesis in Response to Localized Delivery of Macrophage-Recruiting Molecules.
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In vitro functional testing of endothelial progenitor cells that overexpress thrombomodulin.
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In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.
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In vivo performance of dual ligand augmented endothelialized expanded polytetrafluoroethylene vascular grafts.
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Increased miR-21-3p in Injured Brain Microvascular Endothelial Cells after Traumatic Brain Injury Aggravates Blood-Brain Barrier Damage by Promoting Cellular Apoptosis and Inflammation through Targeting MAT2B.
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Increased mobilisation of circulating endothelial progenitors in von Hippel-Lindau disease and renal cell carcinoma.
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Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering.
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Individual and combined effects of shear stress magnitude and spatial gradient on endothelial cell gene expression
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Induction of apoptosis in circulating angiogenic cells by microparticles.
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Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice.
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Inflammation and circulating endothelial progenitor cells in patients with coronary artery disease and residual platelet reactivity.
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Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis.
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Influence of diabetes and perivascular allogeneic endothelial cell implants on arteriovenous fistula remodeling.
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Inhibition of endothelial activation: a new way to treat cerebral malaria?
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Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells.
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Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting.
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Intracellular communication and immunothrombosis in sepsis.
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Intradialytic hypertension and its association with endothelial cell dysfunction.
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Intramyocardial, autologous CD34+ cell therapy for refractory angina.
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Intravital fluorescence facilitates measurement of multiple physiologic functions and gene expression in tumors of live animals.
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Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds.
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Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy.
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Isolation of functional human endothelial cells from small volumes of umbilical cord blood.
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JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids.
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Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells.
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Knockdown of mouse VCAM-1 by vector-based siRNA.
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LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target.
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Laminin alpha 2 enables glioblastoma stem cell growth.
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Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers.
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Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis.
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Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells.
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Localized delivery of nitric oxide from hydrogels inhibits neointima formation in a rat carotid balloon injury model.
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Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome.
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Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model.
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Loss of Endothelial Hypoxia Inducible Factor-Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis.
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Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
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Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy from the VA Enhanced Fitness trial.
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MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure.
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Macrophage-derived Hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni.
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Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite.
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Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice.
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Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.
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Measurement of cell migration on surface-bound fibronectin gradients.
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Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow.
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Mechanotransmission in endothelial cells subjected to oscillatory and multi-directional shear flow.
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Metastatic clear cell renal cell carcinoma: Circulating biomarkers to guide antiangiogenic and immune therapies.
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Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells.
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MiR-21 alleviates secondary blood-brain barrier damage after traumatic brain injury in rats.
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Micron-scale spatially patterned, covalently immobilized vascular endothelial growth factor on hydrogels accelerates endothelial tubulogenesis and increases cellular angiogenic responses.
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Microparticles from aged packed red blood cell units stimulate pulmonary microthrombus formation via P-selectin.
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Micropatterning of poly(ethylene glycol) diacrylate hydrogels with biomolecules to regulate and guide endothelial morphogenesis.
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Microrheology of hyaluronan solutions: implications for the endothelial glycocalyx.
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Mimicking brain tumor-vasculature microanatomical architecture via co-culture of brain tumor and endothelial cells in 3D hydrogels.
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Mitogen-activated protein kinase phosphatase-1 promotes neovascularization and angiogenic gene expression.
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Modification of polyurethaneurea with PEG and YIGSR peptide to enhance endothelialization without platelet adhesion.
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Modulating the mechanical properties of self-assembled peptide hydrogels via native chemical ligation.
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Modulation of Xenogeneic T-cell Proliferation by B7 and mTOR Blockade of T Cells and Porcine Endothelial Cells.
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Molecular characterization of hypoxia-hypothermia-conditioned human endothelial cells and their interaction with human monocytes.
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Molecular profile and partial functional analysis of novel endothelial cell-derived growth factors that regulate hematopoiesis.
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Monocyte-derived CD40 expression is regulated by interferon-γ/interferon-γ receptor-1 pathway when acting as a bridge during their interaction with T cells and allogeneic endothelial cells.
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Morquio syndrome: electron microscopic findings.
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Multicenter phase I/II trial of the safety of allogeneic endothelial cell implants after the creation of arteriovenous access for hemodialysis use: the V-HEALTH study.
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Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices.
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Mylar and Teflon-AF as cell culture substrates for studying endothelial cell adhesion.
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NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation.
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NF-kappaB inhibition by an adenovirus expressed aptamer sensitizes TNFalpha-induced apoptosis.
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NO inhibits hyperoxia-induced NF-κB activation in neonatal pulmonary microvascular endothelial cells.
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Neutrophil accumulation and NET release contribute to thrombosis in HIT.
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Nitric Oxide-Dependent Endothelial Dysfunction and Reduced Arginine Bioavailability in Plasmodium vivax Malaria but No Greater Increase in Intravascular Hemolysis in Severe Disease.
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Nitric oxide-generating hydrogels inhibit neointima formation.
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Normal and shear stresses influence the spatial distribution of intracellular adhesion molecule-1 expression in human umbilical vein endothelial cells exposed to sudden expansion flow.
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Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema.
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Nuclear Receptor Atlases of Choroidal Tissues Reveal Candidate Receptors Associated with Age-Related Macular Degeneration.
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Off-target properties of pharmacotherapy and the importance of mechanistic investigations in early clinical phase drug development.
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Off-the-shelf, heparinized small diameter vascular graft limits acute thrombogenicity in a porcine model.
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Oncolytic HSV exerts direct antiangiogenic activity in ovarian carcinoma.
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Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
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Optimization and Evaluation of a Multiplex Quantitative PCR Assay for Detection of Nucleic Acids in Human Blood Samples from Patients with Spotted Fever Rickettsiosis, Typhus Rickettsiosis, Scrub Typhus, Monocytic Ehrlichiosis, and Granulocytic Anaplasmosis.
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Orthotopic Transplantation of Human Bioartificial Lung Grafts in a Porcine Model: A Feasibility Study.
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Outside the fiber: Endomysial stromal and capillary pathology in skeletal muscle may impede infusion therapy in infantile-onset Pompe disease.
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Oxidative stress impact on barrier function of porcine angular aqueous plexus cell monolayers.
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Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase.
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Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway.
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Ozone exposure is associated with acute changes in inflammation, fibrinolysis, and endothelial cell function in coronary artery disease patients.
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PECAM-1: conflicts of interest in inflammation.
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PECAM-1: regulator of endothelial junctional integrity.
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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
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Paracrine signals from mesenchymal cell populations govern the expansion and differentiation of human hepatic stem cells to adult liver fates.
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Parallel-plate flow chamber and continuous flow circuit to evaluate endothelial progenitor cells under laminar flow shear stress.
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Patient-derived endothelial progenitor cells improve vascular graft patency in a rodent model.
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Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials.
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Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway.
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Periprostatic adipose tissue from obese prostate cancer patients promotes tumor and endothelial cell proliferation: a functional and MR imaging pilot study.
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Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium.
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Phenotypes of trypsin- and collagenase-prepared bovine corneal endothelial cells in the presence of a selective Rho kinase inhibitor, Y-27632.
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Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells.
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Phenotypic characterization of murine models of cerebral cavernous malformations.
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Physiologic Consequences of Caveolin-1 Ablation in Conventional Outflow Endothelia.
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Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stress.
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Pigment epithelium-derived factor targets endothelial and epithelial cells in Wilms' tumor.
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Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue.
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Podocalyxin is a key negative regulator of human endometrial epithelial receptivity for embryo implantation.
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Point-of-Care Rapid-Seeding Ventricular Assist Device with Blood-Derived Endothelial Cells to Create a Living Antithrombotic Coating.
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Point-of-care seeding of nitinol stents with blood-derived endothelial cells.
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Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2.
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Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells.
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Pollutant particles produce vasoconstriction and enhance MAPK signaling via angiotensin type I receptor.
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Porcine endothelial cells cocultured with smooth muscle cells became procoagulant in vitro.
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Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity.
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Potential therapeutic targets for age-related macular degeneration: The nuclear option.
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Pre-transplant Screening for Non-HLA Antibodies: Who should be Tested?
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Preoteomics, metabolomics and circulating endothelial progenitor cells in acute coronary syndromes.
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Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness.
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Projected t-SNE for batch correction.
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Quantitative analysis of biomarkers defines an optimal biological dose for recombinant human endostatin in primary human tumors.
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Quantitative enumeration of vascular smooth muscle cells and endothelial cells derived from bone marrow precursors in experimental choroidal neovascularization.
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RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells.
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ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm.
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Radiosensitizing the Vasculature of Primary Brainstem Gliomas Fails to Improve Tumor Response to Radiation Therapy.
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Rap1 GTPase inhibits leukocyte transmigration by promoting endothelial barrier function.
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Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection.
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Rate of change in central corneal thickness: a viability indicator for conventional drainage tissues in organ culture.
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Recent advances in the research and management of sepsis-associated DIC.
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Recruitment of marrow-derived endothelial cells to experimental choroidal neovascularization by local expression of vascular endothelial growth factor.
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Regulation of TGF-β receptor hetero-oligomerization and signaling by endoglin.
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Regulation of endothelial cell activation and angiogenesis by injectable peptide nanofibers.
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Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity.
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Release of intracellular calcium stores facilitates coxsackievirus entry into polarized endothelial cells.
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Repeated primary blast injury causes delayed recovery, but not additive disruption, in an in vitro blood-brain barrier model.
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Revisiting the determinants of the glomerular filtration barrier: what goes round must come round.
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RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration.
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Rivaroxaban in Outpatients with Mild or Moderate COVID-19: Rationale and Design of the Study CARE (CARE - Coalition COVID-19 Brazil VIII).
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Role and regulation of sickle red cell interactions with other cells: ICAM-4 and other adhesion receptors.
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Role of repulsive factors in vascularization dynamics.
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Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease.
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STAT3-mediated coincidence detection regulates noncanonical immediate early gene induction.
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Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus.
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Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway.
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Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis.
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Self-assembled innervated vasculature-on-a-chip to study nociception.
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Self-assembling peptide-polymer hydrogels designed from the coiled coil region of fibrin.
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Sensitization of Endothelial Cells to Ionizing Radiation Exacerbates Delayed Radiation Myelopathy in Mice.
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Sensitization of Vascular Endothelial Cells to Ionizing Radiation Promotes the Development of Delayed Intestinal Injury in Mice.
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Sensitization to endothelial cell antigens: Unraveling the cause or effect paradox.
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Separation of two phenotypically similar cell types via a single common marker in microfluidic channels.
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Sequential paracrine mechanisms are necessary for the therapeutic benefits of stem cell therapy.
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Sevuparin binds to multiple adhesive ligands and reduces sickle red blood cell-induced vaso-occlusion.
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Shear stress-triggered nitric oxide release from Schlemm's canal cells.
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Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms.
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Significance of lipid composition in a blood-brain barrier-mimetic PAMPA assay.
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Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model.
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Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.
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Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla.
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Skeletal muscle-specific genetic determinants contribute to the differential strain-dependent effects of hindlimb ischemia in mice.
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Sphingosine-1-phosphate signaling regulates lamellipodia localization of cortactin complexes in endothelial cells.
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Statistical hemodynamics: a tool for evaluating the effect of fluid dynamic forces on vascular biology in vivo.
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Stiffening Matrix Induces Age-Mediated Microvascular Phenotype Through Increased Cell Contractility and Destabilization of Adherens Junctions.
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Streptavidin binding and endothelial cell adhesion to biotinylated fibronectin.
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Sulfonylurea receptor 1 expression is variable in adult and pediatric brain tumors.
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Suppression of aberrant choroidal neovascularization through activation of the aryl hydrocarbon receptor.
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Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy.
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Surface projections of titanium substrates increase antithrombotic endothelial function in response to shear stress.
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Sustenance of endothelial cell stability in septic mice through appropriate activation of transient receptor potential vanilloid-4.
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Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues.
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Synergistic effect of shear stress and streptavidin-biotin on the expression of endothelial vasodilator and cytoskeleton genes.
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Synergistic induction of mitogen-activated protein kinase phosphatase-1 by thrombin and epidermal growth factor requires vascular endothelial growth factor receptor-2.
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TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts.
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Targeted Delivery of Cell Softening Micelles to Schlemm's Canal Endothelial Cells for Treatment of Glaucoma.
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Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival.
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Targeting VE-PTP phosphatase protects the kidney from diabetic injury.
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Targeting the Tie2/Tek receptor in astrocytomas.
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Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.
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Temporal modulation of collective cell behavior controls vascular network topology.
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Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad.
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Testis formation in the fetal mouse: dynamic and complex de novo tubulogenesis.
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Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability.
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The Disruption of the Endothelial Barrier Contributes to Acute Lung Injury Induced by Coxsackievirus A2 Infection in Mice.
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The biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells: EPC-seeded antithrombotic Ti implants.
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The coagulopathy, endotheliopathy, and vasculitis of COVID-19.
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The design of a heterocellular 3D architecture and its application to monitoring the behavior of cancer cells in response to the spatial distribution of endothelial cells.
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The effect of aspirin on endothelial progenitor cell biology: preliminary investigation of novel properties.
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The effect of vascular endothelial growth factor (VEGF) presentation within fibrin matrices on endothelial cell branching
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The effects of nicotine on vascular smooth muscle cell chemotaxis induced by thrombospondin-1 and fibronectin.
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The effects of smoking on levels of endothelial progenitor cells and microparticles in the blood of healthy volunteers.
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The expression of microvesicles in the blood of patients with Graves' disease and its relationship to treatment.
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The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organs.
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The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells.
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The interleukin-2 receptor α chain (CD25) plays an important role in regulating monocyte-derived CD40 expression during anti-porcine cellular responses.
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The p53 Transactivation Domain 1-Dependent Response to Acute DNA Damage in Endothelial Cells Protects against Radiation-Induced Cardiac Injury.
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The pathobiology of vascular malformations: insights from human and model organism genetics.
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The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF
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The relationship between plasma microparticles and disease manifestations in patients with systemic sclerosis.
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The role of carrier size in the pharmacodynamics of antisense and siRNA oligonucleotides.
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The role of epigenetics in the endothelial cell shear stress response and atherosclerosis
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The swan genome and transcriptome, it is not all black and white.
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The use of mild trypsinization conditions in the detachment of endothelial cells to promote subsequent endothelialization on synthetic surfaces.
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The vital role for nitric oxide in intraocular pressure homeostasis.
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Therapeutic efficacy of endostatin exhibits a biphasic dose-response curve.
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Therapeutic potential of endothelial progenitor cells in cardiovascular diseases.
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Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening.
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Three-dimensional bioprinting of aneurysm-bearing tissue structure for endovascular deployment of embolization coils.
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Three-dimensional culture conditions differentially affect astrocyte modulation of brain endothelial barrier function in response to transforming growth factor β1.
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Thrombospondin-based antiangiogenic therapy.
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Tie2(+) bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injury.
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Tissue engraftment of hypoxic-preconditioned adipose-derived stem cells improves flap viability.
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Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration.
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Transcriptional regulation of Bim by FOXO3a and Akt mediates scleroderma serum-induced apoptosis in endothelial progenitor cells.
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Transendothelial migration enhances integrin-dependent human neutrophil chemokinesis.
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Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice.
-
Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.
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Tumor Endothelial Cells with Distinct Patterns of TGFβ-Driven Endothelial-to-Mesenchymal Transition.
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Tumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapy.
-
Tumor necrosis factor-α pathway plays a critical role in regulating interferon-γ induced protein-10 production in initial allogeneic human monocyte-endothelial cell interactions.
-
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.
-
Ultrastructural Analysis of Vesicular Transport in Electrotransfection.
-
Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro.
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Underlying potential: cellular and molecular determinants of adult liver repair.
-
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells.
-
Up-regulation of tissue factor in human pulmonary artery endothelial cells after ultrafine particle exposure.
-
Use of autologous blood-derived endothelial progenitor cells at point-of-care to protect against implant thrombosis in a large animal model.
-
VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.
-
VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting.
-
Vascular endothelial cells produce soluble factors that mediate the recovery of human hematopoietic stem cells after radiation injury.
-
Vascular leukocytes: a population with angiogenic and immunossuppressive properties highly represented in ovarian cancer.
-
Vascular-targeted photothermal therapy of an orthotopic murine glioma model.
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Vascularization of engineered tissues: approaches to promote angio-genesis in biomaterials.
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Viscoelastic response of a model endothelial glycocalyx.
-
Wnt2 coordinates the commitment of mesoderm to hematopoietic, endothelial, and cardiac lineages in embryoid bodies.
-
Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells.
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[LMP-420, a new therapeutic approach for cerebral malaria?].
-
p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice.
-
β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability.
-
Keywords of People
-
-
Chen, Jun,
Professor of Medicine,
Duke Cancer Institute
-
Choi, Steven Sok,
Associate Professor of Medicine,
Medicine, Gastroenterology
-
Cianciolo, George James,
Associate Professor Emeritus of Pathology,
Pathology
-
Doan, Phuong Linh,
Associate Professor of Medicine,
Duke Cancer Institute
-
Erickson, Harold Paul,
James B. Duke Distinguished Professor Emeritus,
Cell Biology
-
Laskowitz, Daniel Todd,
Professor of Neurology,
Duke Science & Society
-
McLendon, Roger Edwin,
Professor of Pathology,
Pathology
-
Milano, Carmelo Alessio,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Surgery, Cardiovascular and Thoracic Surgery
-
Miller Jr., Francis Joseph,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
-
Muir, Kelly Walton,
Associate Professor of Ophthalmology,
Ophthalmology, Glaucoma
-
Sullivan, Daniel Carl,
Professor Emeritus of Radiology,
Radiology
-
Sunday, Mary Elizabeth Anne,
Professor of Pathology,
Cell Biology
-
Zennadi, Rahima,
Associate Professor in Medicine,
Pathology