Methylenetetrahydrofolate Reductase (NADPH2)
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Subject Areas on Research
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5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer.
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A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
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A meta-analysis of MTHFR C677T and A1298C polymorphisms and risk of acute lymphoblastic leukemia in children.
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A population model of folate-mediated one-carbon metabolism.
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Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation.
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An alternative pseudolikelihood method for multivariate random-effects meta-analysis.
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Association analysis of the COMT/MTHFR genes and geriatric depression: an MRI study of the putamen.
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Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies.
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Authors' response.
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Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain.
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Folate intake, markers of folate status and oral clefts: is the evidence converging?
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Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression.
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Genetic association analyses of nitric oxide synthase genes and neural tube defects vary by phenotype.
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Genetic variation in glutathione S-transferase omega-1, arsenic methyltransferase and methylene-tetrahydrofolate reductase, arsenic exposure and bladder cancer: a case-control study.
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Inherited thrombophilia in childhood arterial stroke: data from Lebanon.
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Maternal homozygosity for the common MTHFR mutation as a potential risk factor for offspring with limb defects.
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Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers.
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Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease.
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Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.
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Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population.
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Methylenetetrahydrofolate reductase polymorphisms/haplotypes and risk of gastric cancer: a case-control analysis in China.
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Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study.
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Polymorphisms of methylene-tetrahydrofolate reductase and risk of lung cancer: a case-control study.
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Possible interaction of genotypes at cystathionine beta-synthase and methylenetetrahydrofolate reductase (MTHFR) in neural tube defects. NTD Collaborative Group.
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Predicting toxicity from radiation therapy--it's genetic, right?
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Prevalence of factor V G1691A (Leiden), prothrombin G20210A, and methylene tetrahydrofolate reductase C677T thrombophilic mutations in children with inflammatory bowel disease.
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Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability.
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Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians.
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Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE).
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Sex differences in risk of lung cancer associated with methylene-tetrahydrofolate reductase polymorphisms.
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Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction.
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Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury.
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The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
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The relationship between methylenetetrahydrofolate reductase polymorphism and hematological malignancy.
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The thermolabile variant of methylenetetrahydrofolate reductase (MTHFR) is not a major risk factor for neural tube defect in American Caucasians. The NTD Collaborative Group.
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Updated investigations of the role of methylenetetrahydrofolate reductase in human neural tube defects.
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Keywords of People