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Subject Areas on Research
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450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy.
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5-Hydroxymethylcytosine (5hmC) and Ten-eleven translocation 1-3 (TET1-3) proteins in the dorsal root ganglia of mouse: Expression and dynamic regulation in neuropathic pain.
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CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments.
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A DNA methylation biomarker of alcohol consumption.
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A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer.
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A genetic memory initiates the epigenetic loop necessary to preserve centromere position.
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A longitudinal study of epigenetic variation in twins.
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A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance.
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A non-canonical RNAi pathway controls virulence and genome stability in Mucorales.
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A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line.
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A three-generation approach in biodemography is based on the developmental profiles and the epigenetics of female gametes.
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A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.
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ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer.
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ASO Visual Abstract: Machine Learning-Based Epigenetic Classifiers for Axillary Staging of Patients with ER-Positive Early-Stage Breast Cancer.
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Accelerated epigenetic age as a biomarker of cardiovascular sensitivity to traffic-related air pollution.
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Accelerated epigenetic aging in newborns with Down syndrome.
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Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk.
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Age-associated epigenetic change in chimpanzees and humans.
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Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.
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Age-related variations in the methylome associated with gene expression in human monocytes and T cells.
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Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming.
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An epigenetic biomarker of aging for lifespan and healthspan.
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An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents.
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An epigenetic pathway approach to investigating associations between prenatal exposure to maternal mood disorder and newborn neurobehavior.
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An epigenetic pathway in rice connects genetic variation to anaerobic germination and seedling establishment.
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An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.
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An overview of naturally occurring histone deacetylase inhibitors.
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Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood.
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Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.
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Antifungal drug resistance evoked via RNAi-dependent epimutations.
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Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
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Are epigenetic changes in the intrauterine environment related to newborn neurobehavior?
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Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology.
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Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis.
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Association between sleep disordered breathing and epigenetic age acceleration: Evidence from the Multi-Ethnic Study of Atherosclerosis.
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Association of Neighborhood Disadvantage in Childhood With DNA Methylation in Young Adulthood.
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Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring.
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Associations between imprinted gene differentially methylated regions, appetitive traits and body mass index in children.
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Associations between oxytocin receptor gene (OXTR) methylation, plasma oxytocin, and attachment across adulthood.
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BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells.
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Bacterial infection remodels the DNA methylation landscape of human dendritic cells.
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Bayesian genome- and epigenome-wide association studies with gene level dependence.
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Behavioral epigenetics and the developmental origins of child mental health disorders.
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Beyond genotype: serotonin transporter epigenetic modification predicts human brain function.
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Bimodal quantitative relationships between histone modifications for X-linked and autosomal loci.
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Biogenetic mechanisms predisposing to complex phenotypes in parents may function differently in their children.
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Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter.
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Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis.
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Body mass index associated with genome-wide methylation in breast tissue.
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Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes.
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Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides.
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Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.
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CBX2 is required to stabilize the testis pathway by repressing Wnt signaling.
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CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements.
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CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells.
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COPD: balancing oxidants and antioxidants.
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Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs.
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Caenorhabditis elegans as an emerging model system in environmental epigenetics.
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Can we identify meaningful epigenetic effects on human brain function and related risk for mental illness?
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Can we observe epigenetic effects on human brain function?
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Cancer susceptibility: epigenetic manifestation of environmental exposures.
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Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010.
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Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancer.
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Cell-type-dependent histone demethylase specificity promotes meiotic chromosome condensation in Arabidopsis.
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Changes in Neuroimmune and Neuronal Death Markers after Adolescent Alcohol Exposure in Rats are Reversed by Donepezil.
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Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.
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Chromatin and DNA replication.
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Chromatin architecture reorganization during stem cell differentiation.
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Clinical-pathological correlations of BAV and the attendant thoracic aortopathies. Part 2: Pluridisciplinary perspective on their genetic and molecular origins.
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Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
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Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.
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Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.
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Cohort profile: Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort study.
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Common non-epigenetic drugs as epigenetic modulators.
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Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.
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Comparative analysis of metazoan chromatin organization.
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Comparative analysis reveals distinctive epigenetic features of the human cerebellum.
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Comparative cellular analysis of motor cortex in human, marmoset and mouse.
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Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.
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Complete genomic and epigenetic maps of human centromeres.
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Comprehensive functional genomic resource and integrative model for the human brain.
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Computational analysis reveals a correlation of exon-skipping events with splicing, transcription and epigenetic factors.
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Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.
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Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer.
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Core and region-enriched networks of behaviorally regulated genes and the singing genome.
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DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.
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DNA Methylation in Babies Born to Nonsmoking Mothers Exposed to Secondhand Smoke during Pregnancy: An Epigenome-Wide Association Study.
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DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.
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DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial.
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DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies.
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DNA methylation and miRNA expression profiling in childhood B-cell acute lymphoblastic leukemia.
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DNA methylation in epigenetic control of gene expression.
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DNA methylation of NR3c1 in infancy: Associations between maternal caregiving and infant sex.
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DNA methylation of imprinted gene control regions in the regression of low-grade cervical lesions.
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DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma.
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DNA methylation profiles are associated with complex regional pain syndrome after traumatic injury.
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DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.
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DNA methylation signatures reflect aging in patients with nonalcoholic steatohepatitis.
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Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity.
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Decrease in the lgl tumor suppressor dose in Drosophila increases survival and longevity in stress conditions.
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Deletion of a conserved cis-element in the Ifng locus highlights the role of acute histone acetylation in modulating inducible gene transcription.
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Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma.
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Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo.
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Development of germ cells in the mouse.
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Developmental programming of brain and behavior by perinatal diet: focus on inflammatory mechanisms.
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Dicentric chromosomes: unique models to study centromere function and inactivation.
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Dietary Methionine in T Cell Biology and Autoimmune Disease.
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Differential DNA methylation patterns in human Schlemm's canal endothelial cells with glaucoma.
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Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape.
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Differential Gene Expression and DNA Methylation in the Risk of Depression in LOAD Patients.
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Direct evidence for (G)O6···H2-N4(C)+ hydrogen bonding in transient G(syn)-C+ and G(syn)-m5C+ Hoogsteen base pairs in duplex DNA from cytosine amino nitrogen off-resonance R1ρ relaxation dispersion measurements.
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Disparities in Cervical Cancer Incidence and Mortality: Can Epigenetics Contribute to Eliminating Disparities?
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Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes.
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Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion.
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Does evolutionary theory need a rethink?
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Donepezil Reverses Dendritic Spine Morphology Adaptations and Fmr1 Epigenetic Modifications in Hippocampus of Adult Rats After Adolescent Alcohol Exposure.
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Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.
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Drug-Resistant Epimutants Exhibit Organ-Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides.
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DunedinPACE, a DNA methylation biomarker of the pace of aging.
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Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.
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Dysregulated metabolism contributes to oncogenesis.
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Dysregulation of DGCR6 and DGCR6L: psychopathological outcomes in chromosome 22q11.2 deletion syndrome.
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Early adaptive chromatin remodeling events precede pathologic phenotypes and are reinforced in the failing heart.
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Early adversities accelerate epigenetic aging into adulthood: a 10-year, within-subject analysis.
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Early de novo DNA methylation and prolonged demethylation in the muscle lineage.
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Early-life prevention of non-communicable diseases.
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Editing the epigenome: technologies for programmable transcription and epigenetic modulation.
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Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature.
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Emerging antiviral therapeutics for human adenovirus infection: Recent developments and novel strategies.
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Enchondromatosis and Growth Plate Development.
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Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16INK4a.
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Epigenetic Clocks.
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Epigenetic Programming by Maternal Behavior in the Human Infant.
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Epigenetic Regulation of Fanconi Anemia Genes Implicates PRMT5 Blockage as a Strategy for Tumor Chemosensitization.
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Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia.
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Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition.
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Epigenetic Signatures Predict Pathologic Nodal Stage in Breast Cancer Patients with Estrogen Receptor-Positive, Clinically Node-Positive Disease.
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Epigenetic Signatures of Cigarette Smoking.
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Epigenetic Silencing of Recombinant Adeno-associated Virus Genomes by NP220 and the HUSH Complex.
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Epigenetic Switch-Induced Viral Mimicry Evasion in Chemotherapy-Resistant Breast Cancer.
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Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection.
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Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees.
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Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC).
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Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
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Epigenetic and epitranscriptomic regulation of viral replication.
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Epigenetic assimilation in the aging human brain.
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Epigenetic basis for the development of depression in children.
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Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.
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Epigenetic control of intestinal barrier function and inflammation in zebrafish.
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Epigenetic deregulation in pediatric acute lymphoblastic leukemia.
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Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii.
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Epigenetic dysregulation of Oxtr in Tet1-deficient mice has implications for neuropsychiatric disorders.
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Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders.
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Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage.
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Epigenetic markers in rectal cancer.
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Epigenetic mechanisms of drug resistance in fungi.
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Epigenetic mechanisms underlying diet-sourced compounds in the prevention and treatment of gastrointestinal cancer.
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Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells.
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Epigenetic regulation of AXL and risk of childhood asthma symptoms.
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Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells.
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Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication.
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Epigenetic regulation of COL15A1 in smooth muscle cell replicative aging and atherosclerosis.
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Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status.
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Epigenetic regulation of human gamma-glutamyl hydrolase activity in acute lymphoblastic leukemia cells.
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Epigenetic regulation of male fate commitment from an initially bipotential system.
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Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target.
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Epigenetic silencing by the SMC5/6 complex mediates HIV-1 latency.
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Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182.
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Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.
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Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
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Epigenetic variation in OPRM1 gene in opioid-exposed mother-infant dyads.
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Epigenetics and autism spectrum disorder: A report of an autism case with mutation in H1 linker histone HIST1H1E and literature review.
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Epigenetics and cancer metabolism.
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Epigenetics and the regulation of stress vulnerability and resilience.
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Epigenetics and the transition from acute to chronic pain.
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Epigenetics as a new avenue for the role of inbreeding depression in evolutionary ecology.
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Epigenetics in brain function.
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Epigenetics in dilated cardiomyopathy.
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Epigenetics of chronic pain after thoracic surgery.
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Epigenome-wide Association Study Analysis of Calorie Restriction in Humans, CALERIETM Trial Analysis.
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Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults.
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Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
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Epigenome-wide association study of metabolic syndrome in African-American adults.
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Epigenome-wide meta-analysis of DNA methylation and childhood asthma.
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Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR.
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Epigenomic comparison reveals activation of "seed" enhancers during transition from naive to primed pluripotency.
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Epigenomic links from metabolism-methionine and chromatin architecture.
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Epigenomic regulation of heart failure: integrating histone marks, long noncoding RNAs, and chromatin architecture.
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Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.
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Epigenomics of centromere assembly and function.
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Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication.
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Erythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohort.
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Establishing a generalized polyepigenetic biomarker for tobacco smoking.
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Establishing the epigenetic status of the Prader-Willi/Angelman imprinting center in the gametes and embryo.
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Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping.
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Evaluating DNA methylation age on the Illumina MethylationEPIC Bead Chip.
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Exaggerated CpH methylation in the autism-affected brain.
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Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine.
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Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis.
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Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis
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Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST).
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Folic acid throughout pregnancy: too much?
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Food-Grade TiO2
Particles Generate Intracellular Superoxide and Alter Epigenetic Modifiers in Human Lung Cells.
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Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer.
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From induction to conduction: how intrinsic transcriptional priming of extrinsic neuronal connectivity shapes neuronal identity.
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G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program.
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GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
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Genetic Association Between Epigenetic Aging-Acceleration and the Progression of Mild Cognitive Impairment to Alzheimer's Disease.
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Genetic and epigenetic engines of diversity in pathogenic microbes.
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Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.
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Genetic assimilation and accommodation: Models and mechanisms.
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Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates.
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Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression.
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Genome organization and three kinds of heritable changes: general description and stochastic factors (a review).
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Genome-scale screen for DNA methylation-based detection markers for ovarian cancer.
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Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
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Genome-wide chromatin state transitions associated with developmental and environmental cues.
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Genome-wide identification of autosomal genes with allelic imbalance of chromatin state.
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Genome-wide quantification of the effects of DNA methylation on human gene regulation.
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Genomic and Epigenetic Foundations of Neocentromere Formation.
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Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.
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Genomic complexity is associated with epigenetic regulator mutations and poor prognosis in diffuse large B-cell lymphoma.
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Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment.
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Global and gene-specific DNA methylation across multiple tissues in early infancy: implications for children's health research.
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Global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain.
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Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding.
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Growth-Phase-Specific Modulation of Cell Morphology and Gene Expression by an Archaeal Histone Protein.
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HIV-1 Proviral Transcription and Latency in the New Era.
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Harnessing epigenetic variability for crop improvement: current status and future prospects.
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High social status males experience accelerated epigenetic aging in wild baboons.
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High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure.
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Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
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Histone Deacetylase Inhibitors: An Attractive Therapeutic Strategy Against Breast Cancer.
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Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism.
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Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3.
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Histone modifications and chromatin organization in prostate cancer.
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Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing.
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Hypoexpression and epigenetic regulation of candidate tumor suppressor gene CADM-2 in human prostate cancer.
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Identical twins carry a persistent epigenetic signature of early genome programming.
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Identification and characterization of a functional zebrafish smrt corepressor (ncor2).
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Identification of a novel epigenetic regulatory region within the pluripotency associated microRNA cluster, EEmiRC.
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Identification of functional elements and regulatory circuits by Drosophila modENCODE.
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Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.
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Imprint regulatory elements as epigenetic biosensors of exposure in epidemiological studies.
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In-utero epigenetic factors are associated with early-onset myopia in young children.
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Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy.
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Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers.
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Incorporating epigenetic mechanisms to advance fetal programming theories.
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Influence of threonine metabolism on S-adenosylmethionine and histone methylation.
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Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.
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Integrating genetic and epigenetic factors in chronic myeloid leukemia risk assessment: toward gene expression-based biomarkers.
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Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions.
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Integrative functional genomic analysis of human brain development and neuropsychiatric risks.
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Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism.
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Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
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Intergenic and genic sequence lengths have opposite relationships with respect to gene expression.
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Interplay between SCARECROW, GA and LIKE HETEROCHROMATIN PROTEIN 1 in ground tissue patterning in the Arabidopsis root.
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Intracellular Generation of Superoxide by TiO2
Nanoparticles Decreases Histone Deacetylase 9 (HDAC9), an Epigenetic Modifier.
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Introduction to the Special Section on Epigenetics.
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Is epigenetic inheritance a counterexample to the central dogma?
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K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking.
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Landscape of stimulation-responsive chromatin across diverse human immune cells.
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Leaf chlorosis in Arabidopsis thaliana hybrids is associated with transgenerational decline and imbalanced ribosome number.
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Lifetime marijuana use and epigenetic age acceleration: A 17-year prospective examination.
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Ligament versus bone cell identity in the zebrafish hyoid skeleton is regulated by mef2ca.
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Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.
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Long Noncoding RNAs in Atherosclerosis and Vascular Injury: Pathobiology, Biomarkers, and Targets for Therapy.
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Long noncoding RNA MIR4435-2HG enhances metabolic function of myeloid dendritic cells from HIV-1 elite controllers.
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MATCHER: manifold alignment reveals correspondence between single cell transcriptome and epigenome dynamics.
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Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.
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Machine Learning-Based Epigenetic Classifiers for Axillary Staging of Patients with ER-Positive Early-Stage Breast Cancer.
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Male obesity impacts DNA methylation reprogramming in sperm.
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Mapping and characterization of structural variation in 17,795 human genomes.
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Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.
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Maternal pre-pregnancy obesity, offspring cord blood DNA methylation, and offspring cardiometabolic health in early childhood: an epigenome-wide association study.
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Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2.
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Mechanotransduction mechanisms for intraventricular diastolic vortex forces and myocardial deformations: part 1.
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Menstrual cyclic change of metastin/GPR54 in endometrium.
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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.
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Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation.
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Metabolic Signaling Drives IFN-γ.
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Metabolic decisions in development and disease-a Keystone Symposia report.
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Metabolic interactions with cancer epigenetics.
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Metabolic regulation of epigenetic remodeling in immune cells.
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Methionine metabolism in health and cancer: a nexus of diet and precision medicine.
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Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development.
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Methylation markers of malignant potential in meningiomas.
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Methylation subtypes and large-scale epigenetic alterations in gastric cancer.
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Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms.
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Methylomics of gene expression in human monocytes.
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Modeling folate, one-carbon metabolism, and DNA methylation.
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Models of epigenetic age capture patterns of DNA methylation in glioma associated with molecular subtype, survival, and recurrence.
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Modulation of tissue repair by regeneration enhancer elements.
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Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
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Molecular biology of head and neck cancer: risks and pathways.
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Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis.
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Monocyte miRNAs Are Associated With Type 2 Diabetes.
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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
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Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators.
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NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling.
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NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition.
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Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders.
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New agents and regimens for diffuse large B cell lymphoma.
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New genetic loci link adipose and insulin biology to body fat distribution.
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Noncoding RNAs: biology and applications-a Keystone Symposia report.
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Nongenetic inheritance and multigenerational plasticity in the nematode C. elegans.
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Novel insights into the genetics and epigenetics of MALT lymphoma unveiled by next generation sequencing analyses.
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Novel roles of apoptotic caspases in tumor repopulation, epigenetic reprogramming, carcinogenesis, and beyond.
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Nutrients and the microenvironment to feed a T cell army.
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One-carbon metabolism and epigenetics: understanding the specificity.
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Opposing Epigenetic Signatures in Human Sperm by Intake of Fast Food Versus Healthy Food.
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Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.
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Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells.
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Paternal THC exposure in rats causes long-lasting neurobehavioral effects in the offspring.
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Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort.
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Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism.
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Perinatal risk factors in the development of aggression and violence.
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Pharmacodynamic study of disulfiram in men with non-metastatic recurrent prostate cancer.
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Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.
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Phase separation of chromatin and small RNA pathways in plants.
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Potential therapeutic effect of epigenetic therapy on treatment-induced neuroendocrine prostate cancer.
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Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer.
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Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation.
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Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis.
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RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence.
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Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells.
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Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma.
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Resource base influences genome-wide DNA methylation levels in wild baboons (Papio cynocephalus).
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Reversal of Epigenetic Silencing Allows Robust HIV-1 Replication in the Absence of Integrase Function.
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Ribosome stalling and SGS3 phase separation prime the epigenetic silencing of transposons.
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Role of SIRT1 and Progesterone Resistance in Normal and Abnormal Endometrium.
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Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing.
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Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes.
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Serine, glycine and one-carbon units: cancer metabolism in full circle.
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Sex determination without sex chromosomes.
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Sex-specific fitness effects of unpredictable early life conditions are associated with DNA methylation in the avian glucocorticoid receptor.
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Sexual fidelity trade-offs promote regulatory variation in the prairie vole brain.
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Shaping Chromatin States in Prostate Cancer by Pioneer Transcription Factors.
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Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection.
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Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.
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Snacking frequency and dietary intake in toddlers and preschool children.
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SnapShot: Origins of DNA replication.
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Sparrows and supergenes: Ecological epigenetics in action.
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Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin.
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Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling.
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Structural and functional dynamics of human centromeric chromatin.
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Systematic dissection of phenotypic, functional, and tumorigenic heterogeneity of human prostate cancer cells.
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Systemic acquired resistance: turning local infection into global defense.
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T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation.
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T cell stemness and dysfunction in tumors are triggered by a common mechanism.
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Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells.
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Targeted Exome Sequencing of the Cancer Genome in Patients with Very High-risk Bladder Cancer.
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Targeting Isocitrate Dehydrogenase Mutations in Cancer: Emerging Evidence and Diverging Strategies.
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Targeting the epigenome in ovarian cancer.
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Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome.
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The BLUEPRINT Data Analysis Portal.
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The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.
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The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery.
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The Molecular Taxonomy of Primary Prostate Cancer.
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The Nuclear Pore Complex in Cell Type-Specific Chromatin Structure and Gene Regulation.
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The PsychENCODE project.
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The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.
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The Role of Epigenetic Clocks in Explaining Educational Inequalities in Mortality: A Multicohort Study and Meta-analysis.
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The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study.
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The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality.
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The association between neuraxial anesthesia and the development of childhood asthma - a secondary analysis of the newborn epigenetics study cohort.
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The association of accelerated epigenetic age with all-cause mortality in cardiac catheterization patients as mediated by vascular and cardiometabolic outcomes.
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The diverse culinary habits of microglia.
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The dynamic epitranscriptome: N6-methyladenosine and gene expression control.
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The epigenetics of adaptation: focusing on epigenetic stability as an evolving trait.
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The evolving metabolic landscape of chromatin biology and epigenetics.
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The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis.
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The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells.
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The human imprintome: regulatory mechanisms, methods of ascertainment, and roles in disease susceptibility.
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The impact of cellular metabolism on chromatin dynamics and epigenetics.
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The integrated genomic and epigenomic landscape of brainstem glioma.
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The long non-coding RNA FMR4 promotes proliferation of human neural precursor cells and epigenetic regulation of gene expression in trans.
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The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy.
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The negative side of retinoic acid receptors.
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The role of EVI1 in myeloid malignancies.
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The role of epigenetics in the endothelial cell shear stress response and atherosclerosis
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The role of the extracellular matrix protein TGFBI in cancer.
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The unique DEK oncoprotein in women's health: A potential novel biomarker.
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Therapeutic targets for neuroblastomas.
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Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.
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Transcriptome and epigenome landscape of human cortical development modeled in organoids.
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Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans.
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Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity in Caenorhabditis elegans
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Transgenic mice for in vivo epigenome editing with CRISPR-based systems.
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Traumatic stress and accelerated DNA methylation age: A meta-analysis.
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Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast.
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Unique cell-type-specific patterns of DNA methylation in the root meristem.
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Unmodern Synthesis: Developmental Hierarchies and the Origin of Phenotypes.
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Up-regulation of SNCA gene expression: implications to synucleinopathies.
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Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma.
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Vertebrate sex determination: evolutionary plasticity of a fundamental switch.
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Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity.
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Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.
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Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection.
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Whole-genome fingerprint of the DNA methylome during human B cell differentiation.
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Wnt activation promotes memory T cell polyfunctionality via epigenetic regulator PRMT1.
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Yin yang 1 modulates taxane response in epithelial ovarian cancer.
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lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
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Keywords of People
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Ciofani, Maria,
Associate Professor of Immunology,
Cell Biology
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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Sullivan, Beth Ann,
Professor of Molecular Genetics and Microbiology,
Duke Science & Society
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Yan, Hai,
Adjunct Professor of Pathology,
Pathology