Receptor, Angiotensin, Type 2
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Subject Areas on Research
- AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase.
- AT2 receptor and vascular smooth muscle cell differentiation in vascular development.
- Activation of the de novo biosynthesis of sphingolipids mediates angiotensin II type 2 receptor-induced apoptosis.
- Analysis of functional domains of angiotensin II type 2 receptor involved in apoptosis.
- Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
- Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway.
- Angiotensin II stimulates canonical TGF-β signaling pathway through angiotensin type 1 receptor to induce granulation tissue contraction.
- Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis and antagonizes angiotensin II type 1 receptor action: an in vitro gene transfer study.
- Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium.
- Angiotensin induces the urinary peristaltic machinery during the perinatal period.
- Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor.
- Angiotensin receptor gene polymorphisms and 2-year change in hyperintense lesion volume in men.
- Angiotensin receptor signaling and prostate tumor growth in mice.
- Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease.
- Angiotensin type 2 receptor dephosphorylates Bcl-2 by activating mitogen-activated protein kinase phosphatase-1 and induces apoptosis.
- Angiotensin type 2 receptor is expressed in murine atherosclerotic lesions and modulates lesion evolution.
- Angiotensin-II mediates nonmuscle myosin II activation and expression and contributes to human keloid disease progression.
- Candesartan in heart failure--assessment of reduction in mortality and morbidity (CHARM): rationale and design. Charm-Programme Investigators.
- Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts.
- Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects.
- Cardiovascular phenotype of mice lacking all three subtypes of angiotensin II receptors.
- Characterization of angiotensin II-receptor subtypes in podocytes.
- Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor.
- Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling.
- Divergent functions of angiotensin II receptor isoforms in the brain.
- Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells.
- Effects of candesartan on angiotensin II-induced renal vasoconstriction in rats and mice.
- Essential role of AT1A receptor in the development of 2K1C hypertension.
- Expression of renin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor.
- Genetic manipulation of the renin-angiotensin system.
- Genomic organization and polymorphism of human angiotensin II type 2 receptor: no evidence for its gene mutation in two families of human premature ovarian failure syndrome.
- Immunologic Effects of the Renin-Angiotensin System.
- Increased vasoconstrictor response of the mouse lacking angiotensin II type 2 receptor.
- Inflammation influences vascular remodeling through AT2 receptor expression and signaling.
- Inhibitory effect of angiotensin II type 2 receptor on coronary arterial remodeling after aortic banding in mice.
- Insights into the functions of type 1 (AT1) angiotensin II receptors provided by gene targeting.
- Interferon regulatory factor-1 up-regulates angiotensin II type 2 receptor and induces apoptosis.
- Intracellular third loop domain of angiotensin II type-2 receptor. Role in mediating signal transduction and cellular function.
- Intracellular third loops in AT1 and AT2 receptors determine subtype specificity.
- Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand.
- Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.
- Molecular and cellular mechanism of angiotensin II-mediated apoptosis.
- Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity.
- New insights into angiotensin receptor actions: from blood pressure to aging.
- Quantifying ligand bias at seven-transmembrane receptors.
- Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
- Renal function in the AT1A receptor knockout mouse during normal and volume-expanded conditions.
- Renal vascular reactivity in mice: AngII-induced vasoconstriction in AT1A receptor null mice.
- Renin-angiotensin system gene expression in post-transplant hypertension predicts allograft function.
- Targeted deletion of angiotensin II type 1A receptor does not protect mice from progressive nephropathy of overload proteinuria.
- The renin-angiotensin-aldosterone system: a specific target for hypertension management.
- The role of angiotensin II in stress urinary incontinence: A rat model.
- Type 2 angiotensin II receptor expression in human renal allografts: an association with chronic allograft nephropathy.
- Which inhibitor of the renin-angiotensin system should be used in chronic heart failure and acute myocardial infarction?