Mesenchymal Stem Cell Transplantation
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Subject Areas on Research
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A Phase 3, Single-Arm, Prospective Study of Remestemcel-L, Ex Vivo Culture-Expanded Adult Human Mesenchymal Stromal Cells for the Treatment of Pediatric Patients Who Failed to Respond to Steroid Treatment for Acute Graft-versus-Host Disease.
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Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology.
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Accelerating stem cell trials for Alzheimer's disease.
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Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis.
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Adult human nasal mesenchymal-like stem cells restore cochlear spiral ganglion neurons after experimental lesion.
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Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty.
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Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
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Allogeneic Mesenchymal Stem Cells for Treatment of AKI after Cardiac Surgery.
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Allogeneic human mesenchymal stem cell therapy (remestemcel-L, Prochymal) as a rescue agent for severe refractory acute graft-versus-host disease in pediatric patients.
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Anti-fibrotic effects of different sources of MSC in bleomycin-induced lung fibrosis in C57BL6 male mice.
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Benefit of cardiopoietic mesenchymal stem cell therapy on left ventricular remodelling: results from the Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) study.
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Bone Marrow Mesenchymal Stem Cell Transplantation Increases GAP-43 Expression via ERK1/2 and PI3K/Akt Pathways in Intracerebral Hemorrhage.
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Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial.
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Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome.
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Cellular Therapies in Solid Organ Allotransplantation: Promise and Pitfalls.
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Characterizing differences between MSCs and TM cells: Toward autologous stem cell therapies for the glaucomatous trabecular meshwork.
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Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial design.
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Cord-blood engraftment with ex vivo mesenchymal-cell coculture.
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Does transendocardial injection of mesenchymal stem cells improve myocardial function locally or globally?: An analysis from the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis (POSEIDON) randomized trial.
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Durable scar size reduction due to allogeneic mesenchymal stem cell therapy regulates whole-chamber remodeling.
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Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction.
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Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction.
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Effect of scaffold microarchitecture on osteogenic differentiation of human mesenchymal stem cells.
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Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal™) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study.
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Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury.
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Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction.
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Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement.
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Genetic engineering of mesenchymal stem cells and its application in human disease therapy.
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Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium.
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Histologic changes of mesenchymal stem cell repair of tympanic membrane perforation.
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Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma.
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Immuno-suppressive hydrogels enhance allogeneic MSC survival after transplantation in the injured brain.
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In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells.
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Infusion of human umbilical cord tissue mesenchymal stromal cells in children with autism spectrum disorder.
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Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis.
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Intracardiac transplantation of a mixed population of bone marrow cells improves both regional systolic contractility and diastolic relaxation.
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Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure: A Randomized Clinical Trial.
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Intramyocardial stem cell injection in patients with ischemic cardiomyopathy: functional recovery and reverse remodeling.
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Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.
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Mesenchymal Stem Cell Therapy in Stroke: A Systematic Review of Literature in Pre-Clinical and Clinical Research.
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Mesenchymal precursor cells as adjunctive therapy in recipients of contemporary left ventricular assist devices.
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Mesenchymal stem cell and gene therapies for spinal fusion.
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Mesenchymal stem cells in obesity: insights for translational applications.
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Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation.
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Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment.
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Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease.
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Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment.
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Mesenchymal stromal cells reprogram monocytes and macrophages with processing bodies.
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Meta-analysis of preclinical studies of mesenchymal stromal cells to treat rheumatoid arthritis.
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Morphogenetic signals from chondrocytes promote chondrogenic and osteogenic differentiation of mesenchymal stem cells.
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Osteocel Plus cellular allograft in anterior cervical discectomy and fusion: evaluation of clinical and radiographic outcomes from a prospective multicenter study.
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Outcomes of Bone Grafting of Bone Cysts After Total Ankle Arthroplasty.
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PLX-PAD Cell Treatment of Critical Limb Ischaemia: Rationale and Design of the PACE Trial.
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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.
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Partial Pectoralis Tear Treated With Orthobiologics: A Case Report.
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Poly(ethylene glycol) hydrogels with cell cleavable groups for autonomous cell delivery.
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Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy.
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Rationale and design of the Transendocardial Injection of Autologous Human Cells (bone marrow or mesenchymal) in Chronic Ischemic Left Ventricular Dysfunction and Heart Failure Secondary to Myocardial Infarction (TAC-HFT) trial: A randomized, double-blind, placebo-controlled study of safety and efficacy.
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Rationale and design of the allogeneiC human mesenchymal stem cells (hMSC) in patients with aging fRAilTy via intravenoUS delivery (CRATUS) study: A phase I/II, randomized, blinded and placebo controlled trial to evaluate the safety and potential efficacy of allogeneic human mesenchymal stem cell infusion in patients with aging frailty.
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Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice.
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Regression of cardiac amyloidosis after stem cell transplantation assessed by cardiovascular magnetic resonance imaging.
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Sequential paracrine mechanisms are necessary for the therapeutic benefits of stem cell therapy.
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Stem cell-bearing suture improves Achilles tendon healing in a rat model.
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Study 275: Updated Expanded Access Program for Remestemcel-L in Steroid-Refractory Acute Graft-versus-Host Disease in Children.
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Survival after mesenchymal stromal cell therapy in steroid-refractory acute graft-versus-host disease: systematic review and meta-analysis.
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Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues.
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The effect of mesenchymal stem cell sheets on structural allograft healing of critical sized femoral defects in mice.
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The role of cytokines in posttraumatic arthritis.
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Transendocardial mesenchymal stem cells and mononuclear bone marrow cells for ischemic cardiomyopathy: the TAC-HFT randomized trial.
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X-ray-visible microcapsules containing mesenchymal stem cells improve hind limb perfusion in a rabbit model of peripheral arterial disease.