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Subject Areas on Research
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A 137-kb deletion within the Potocki-Shaffer syndrome interval on chromosome 11p11.2 associated with developmental delay and hypotonia.
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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.
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A low-cost, scalable, current-sensing digital headstage for high channel count μECoG.
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A multispecies-based taxonomic microarray reveals interspecies hybridization and introgression in Saccharomyces cerevisiae.
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A pathobiological role of the insulin receptor in chronic lymphocytic leukemia.
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A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.
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A sea of standards for omics data: sink or swim?
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Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation.
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Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo.
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Afforestation alters the composition of functional genes in soil and biogeochemical processes in South American grasslands.
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Airway epithelial progenitors are region specific and show differential responses to bleomycin-induced lung injury.
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An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
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An individualized predictor of health and disease using paired reference and target samples.
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Angle-dependent resonance of localized and propagating surface plasmons in microhole arrays for enhanced biosensing.
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Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease.
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Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York.
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Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events.
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Assessing transcription factor motif drift from noisy decoy sequences.
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Bayesian semiparametric regression models for evaluating pathway effects on continuous and binary clinical outcomes.
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Carbohydrate Microarrays Identify Blood Group Precursor Cryptic Epitopes as Potential Immunological Targets of Breast Cancer.
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Cellular arrays for large-scale analysis of transcription factor activity.
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Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells.
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Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal.
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Cholangiocarcinoma: Correlation between Molecular Profiling and Imaging Phenotypes.
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Chromosomal microarray analysis in clinical evaluation of neurodevelopmental disorders-reporting a novel deletion of SETDB1 and illustration of counseling challenge.
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Clinical efficacy and immune regulation with peanut oral immunotherapy.
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Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems.
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Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis.
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Convergent differential regulation of parvalbumin in the brains of vocal learners.
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Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer.
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Coordination of replication and transcription along a Drosophila chromosome.
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Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization.
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Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.
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Cryptococcus neoformans gene expression during murine macrophage infection.
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Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model.
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Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization.
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Detection and reporting of homozygosity associated with consanguinity in the clinical laboratory.
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Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients.
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Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo.
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Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge.
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Differential gene expression in normal and transformed human mammary epithelial cells in response to oxidative stress.
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Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain.
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Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells.
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ERG responses and microarray analysis of gene expression in a multifactorial murine model of age-related retinal degeneration.
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Effects of Temperature on the Meiotic Recombination Landscape of the Yeast Saccharomyces cerevisiae.
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Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans.
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Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci.
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Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected].
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Gene Expression Profiling in the Hibernating Primate, Cheirogaleus Medius.
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Gene expression of the endolymphatic sac.
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Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma.
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Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers.
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Genome rearrangements caused by interstitial telomeric sequences in yeast.
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Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
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Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae.
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Genomic and epigenetic evidence for oxytocin receptor deficiency in autism.
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Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer.
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Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival.
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HIV-1 Infection Primes Macrophages Through STAT Signaling to Promote Enhanced Inflammation and Viral Replication.
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Hardware Design and Fault-Tolerant Synthesis for Digital Acoustofluidic Biochips.
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Heterogeneity within the PF-EPN-B ependymoma subgroup.
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High rates of "unselected" aneuploidy and chromosome rearrangements in tel1 mec1 haploid yeast strains.
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High resolution analysis of genomic aberrations by metaphase and array comparative genomic hybridization identifies candidate tumour genes in lung cancer cell lines.
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Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm.
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IFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver.
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Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome.
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Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.
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Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression.
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Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments.
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Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel.
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Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress.
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Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy.
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Isolation and characterization of microRNAs of human mature erythrocytes.
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Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces.
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Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.
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Meeting report: high-throughput technologies for in vivo imaging agents.
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Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development.
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MicroRNA expression profiling using microarrays.
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Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE.
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Microarray-based comparison of three amplification methods for nanogram amounts of total RNA.
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Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers.
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Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.
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Mild fetal ventriculomegaly: diagnosis, evaluation, and management.
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Model-based analysis of multiple electrode array stimulation for epiretinal visual prostheses.
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Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.
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Molecular markers for incidence, prognosis, and response to therapy.
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Molecular staging of epithelial maturation using secretory cell-specific genes as markers.
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NPAS1 regulates branching morphogenesis in embryonic lung.
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Nature and distribution of large sequence polymorphisms in Saccharomyces cerevisiae.
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Neuron-specific SUMO knockdown suppresses global gene expression response and worsens functional outcome after transient forebrain ischemia in mice.
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Oxidatively modified proteins as plasma biomarkers in breast cancer.
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Parallel Glyco-SPOT Synthesis of Glycopeptide Libraries.
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Polyreactivity and autoreactivity among HIV-1 antibodies.
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Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia.
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Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells.
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Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus.
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Sample size considerations of prediction-validation methods in high-dimensional data for survival outcomes.
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Short-lag spatial coherence imaging on matrix arrays, part 1: Beamforming methods and simulation studies.
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Short-lag spatial coherence imaging on matrix arrays, part II: Phantom and in vivo experiments.
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Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay.
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Stem Cell Surface Marker Expression Defines Late Stages of Reprogramming to Pluripotency in Human Fibroblasts.
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TBR-760, a Dopamine-Somatostatin Compound, Arrests Growth of Aggressive Nonfunctioning Pituitary Adenomas in Mice.
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Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia.
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Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad.
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The end game of chemical genetics: target identification.
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The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences.
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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
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The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo.
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Transcriptome changes affecting Hedgehog and cytokine signalling in the umbilical cord: implications for disease risk.
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Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration.
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Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q.
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Unsupervised Bayesian linear unmixing of gene expression microarrays.
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Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates.
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Whole-genome positive selection and habitat-driven evolution in a shallow and a deep-sea urchin.
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miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy.
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permGPU: Using graphics processing units in RNA microarray association studies.
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Keywords of People
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Bowes Rickman, Catherine,
George and Geneva Boguslavsky Distinguished Professor of Eye Research,
Cell Biology
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Hogan, Brigid L. M.,
Research Professor of Cell Biology,
Cell Biology
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Liu, Yutao,
Adjunct Assistant Professor in the Department of Medicine,
Medicine, Medical Genetics
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McLendon, Roger Edwin,
Professor of Pathology,
Pathology
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Pang, Herbert,
Adjunct Assistant Professor in the Department of Biostatistics & Bioinformatics,
Biostatistics & Bioinformatics
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Reddy, Timothy E,
Associate Professor of Biostatistics & Bioinformatics,,
Molecular Genetics and Microbiology
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Soderling, Scott Haydn,
George Barth Geller Distinguished Professor of Molecular Biology,
Cell Biology
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Sullivan, Daniel Carl,
Professor Emeritus of Radiology,
Radiology
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Tenenbaum, Jessica Dale,
Assistant Professor of Biostatistics & Bioinformatics,
Duke Science & Society