Microscopy, Electron, Transmission

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  Subject Areas on Research

  • A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents. 
  • A dynamic broadband reflector built from microscopic silica spheres in the 'disco' clam Ctenoides ales. 
  • A molecular phylogeny of the flagellated fungi (Chytridiomycota) and description of a new phylum (Blastocladiomycota). 
  • A new lineage in Pucciniomycotina: class Tritirachiomycetes, order Tritirachiales, family Tritirachiaceae. 
  • A new method for studying the interaction between chlorpromazine and phospholipid bilayer. 
  • A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells. 
  • A simple route towards CuO nanowires and nanorods. 
  • A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphotericin B and enhances adaptive immunity in murine cutaneous leishmaniasis. 
  • Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver. 
  • Airborne fiber size characterization in exposure estimation: Evaluation of a modified transmission electron microcopy protocol for asbestos and potential use for carbon nanotubes and nanofibers. 
  • Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice. 
  • An apolipoprotein E-mimetic stimulates axonal regeneration and remyelination after peripheral nerve injury. 
  • An epidemiological study of the role of chrysotile asbestos fibre dimensions in determining respiratory disease risk in exposed workers. 
  • An in vivo look at vertebrate liver architecture: three-dimensional reconstructions from medaka (Oryzias latipes). 
  • Anchoring hepatic gene expression with development of fibrosis and neoplasia in a toxicant-induced fish model of liver injury. 
  • Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch. 
  • Antibody-conjugated gold-gold sulfide nanoparticles as multifunctional agents for imaging and therapy of breast cancer. 
  • Assessing the risks of manufactured nanomaterials. 
  • Atractiella rhizophila, sp. nov., an endorrhizal fungus isolated from the Populus root microbiome. 
  • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. 
  • Autophagy is essential for mitochondrial clearance in mature T lymphocytes. 
  • Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line. 
  • BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo. 
  • Best practices for correctly identifying coronavirus by transmission electron microscopy. 
  • Biochemical and structural insights into bacterial organelle form and biogenesis. 
  • Biomaterials directed in vivo osteogenic differentiation of mesenchymal cells derived from human embryonic stem cells. 
  • Biomimetic, synthetic HDL nanostructures for lymphoma. 
  • Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. 
  • COBRA, an Arabidopsis extracellular glycosyl-phosphatidyl inositol-anchored protein, specifically controls highly anisotropic expansion through its involvement in cellulose microfibril orientation. 
  • CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease. 
  • Cadmium(II) removal by a hyperaccumulator fungus Phoma sp. F2 isolated from blende soil. 
  • Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. 
  • Cell-penetrating peptide enhanced intracellular Raman imaging and photodynamic therapy. 
  • Cellular projections from sensory hair cells form polarity-specific scaffolds during synaptogenesis. 
  • Characterization of a trimeric MPER containing HIV-1 gp41 antigen. 
  • Characterization of symbiont populations in life-history stages of mussels from chemosynthetic environments. 
  • Characterization of the axon initial segment of mice substantia nigra dopaminergic neurons. 
  • Chirality affects aggregation kinetics of single-walled carbon nanotubes. 
  • Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus. 
  • Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes. 
  • Co-assembling peptides as defined matrices for endothelial cells. 
  • Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth. 
  • Comments on Dodson et al., A technical comparison of evaluating asbestos concentration by phase contrast microscopy (PCM), scanning electron microscopy (SEM), and analytical transmission electron microscopy (ATEM) as illustrated from data generated from a case report. 
  • Conical electron tomography of a chemical synapse: vesicles docked to the active zone are hemi-fused. 
  • Control of septin filament flexibility and bundling by subunit composition and nucleotide interactions. 
  • Cryo-electron microscopy of biological samples. 
  • Cytoplasmic inclusion bodies are detected by synthetic antibody in ciliated bronchial epithelium during acute Kawasaki disease. 
  • Cytoplasmic sharing through apical membrane remodeling. 
  • Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle. 
  • Development of a fibre size-specific job-exposure matrix for airborne asbestos fibres. 
  • Didodecyldimethylammonium bromide lipid bilayer-protected gold nanoparticles: synthesis, characterization, and self-assembly. 
  • Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps. 
  • Directing and Potentiating Stem Cell-Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating. 
  • Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. 
  • Effect of freeze-thawing on lipid bilayer-protected gold nanoparticles. 
  • Effects of humic acid and electrolytes on photocatalytic reactivity and transport of carbon nanoparticle aggregates in water. 
  • Effects of simvastatin on retinal structure and function of a high-fat atherogenic mouse model of thickened Bruch's membrane. 
  • Efferent synapses return to inner hair cells in the aging cochlea. 
  • Efficient quantification of afferent cochlear ultrastructure using design-based stereology. 
  • Electrochemical and electrochemiluminescence study of Ru(bpy)(2+)3-doped silica nanoparticles with covalently grafted biomacromolecules. 
  • Emerging mechanistic targets in lung injury induced by combustion-generated particles. 
  • Enterotoxigenic Escherichia coli vesicles target toxin delivery into mammalian cells. 
  • Estimates of historical exposures by phase contrast and transmission electron microscopy for pooled exposure--response analyses of North Carolina and South Carolina, USA asbestos textile cohorts. 
  • Estimates of historical exposures by phase contrast and transmission electron microscopy in North Carolina USA asbestos textile plants. 
  • Estrogen receptor beta protects against in vivo injury in RPE cells. 
  • Expression of Kingella kingae type IV pili is regulated by sigma54, PilS, and PilR. 
  • Extracellular trafficking of myocilin in human trabecular meshwork cells. 
  • Extracellular vesicles from endometriosis patients are characterized by a unique miRNA-lncRNA signature. 
  • Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal. 
  • Feasibility of laser trabeculoplasty in angle closure glaucoma: a review of favourable histopathological findings in narrow angles. 
  • Fenofibrate rapidly decreases hepatic lipid and glycogen storage in neonatal mice with glycogen storage disease type Ia. 
  • Fibulin-2 is a driver of malignant progression in lung adenocarcinoma. 
  • Fluorescent epibatidine agonists for neuronal and muscle-type nicotinic acetylcholine receptors. 
  • Fullerol cluster formation in aqueous solutions: implications for environmental release. 
  • Gain modulation by nicotine in macaque v1. 
  • Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly. 
  • Glycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cells. 
  • Gold-nanocrystal-enhanced bioluminescent nanocapsules 
  • Gradated assembly of multiple proteins into supramolecular nanomaterials. 
  • Heparan sulfate, including that in Bruch's membrane, inhibits the complement alternative pathway: implications for age-related macular degeneration. 
  • Hierarchical Self-Assembly of Noncovalent Amphiphiles 
  • High-resolution analytical electron microscopy reveals cell culture media-induced changes to the chemistry of silver nanowires. 
  • Histopathologic and ultrastructural features of surgically excised subfoveal choroidal neovascular lesions: submacular surgery trials report no. 7. 
  • How Copper Nanowires Grow and How To Control Their Properties. 
  • Hunting coronavirus by transmission electron microscopy - a guide to SARS-CoV-2-associated ultrastructural pathology in COVID-19 tissues. 
  • Hydroxychloroquine: a treatable cause of cardiomyopathy. 
  • Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface. 
  • Immunohistochemical characterization of the hepatic progenitor cell compartment in medaka (Oryzias latipes) following hepatic injury. 
  • Impacts of ingested MWCNT-Embedded nanocomposites in Japanese medaka (Oryzias latipes ). 
  • Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin. 
  • Importance of a nanoscience approach in the understanding of major aqueous contamination scenarios: case study from a recent coal ash spill. 
  • In vitro cytotoxicity of silver nanoparticles in primary rat hepatic stellate cells. 
  • In vitro determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells. 
  • In vitro interactions between DMSA-coated maghemite nanoparticles and human fibroblasts: A physicochemical and cyto-genotoxical study. 
  • In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. 
  • In vivo imaging and genetic analysis link bacterial motility and symbiosis in the zebrafish gut. 
  • Intraoperative floppy iris syndrome: report of a case and histopathologic analysis. 
  • Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells. 
  • Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish. 
  • L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro. 
  • Lactobacillus reuteri DSM 20016 produces cobalamin-dependent diol dehydratase in metabolosomes and metabolizes 1,2-propanediol by disproportionation. 
  • Letter to the editor: "Comparing milled fiber, Quebec ore, and textile factory dust: has another piece of the asbestos puzzle fallen into place?" by D. Wayne Berman. 
  • Liposomes-entrapped chondroitin sulphate: ultrastructural characterization and in vitro biocompatibility. 
  • Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations. 
  • Loss of stiffness in collagen-rich uterine fibroids after digestion with purified collagenase Clostridium histolyticum. 
  • Low concentrations of silver nanoparticles in biosolids cause adverse ecosystem responses under realistic field scenario. 
  • Measuring EMPs in the lung what can be measured in the lung: Asbestiform minerals and cleavage fragments. 
  • Mechanisms of photochemistry and reactive oxygen production by fullerene suspensions in water. 
  • Mitochondrial dysfunction in ataxia-telangiectasia. 
  • Modulating the mechanical properties of self-assembled peptide hydrogels via native chemical ligation. 
  • Morphological and genomic characterization of Filobasidiella depauperata: a homothallic sibling species of the pathogenic cryptococcus species complex. 
  • Morphology and ultrastructure of differentiating three-dimensional mammalian skeletal muscle in a collagen gel. 
  • Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices. 
  • Multilamellar spherical particles as potential sources of excessive light scattering in human age-related nuclear cataracts. 
  • Mutations near amino end of alpha1(I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing. 
  • Myotilin overexpression enhances myopathology in the LGMD1A mouse model. 
  • Nanoparticle delivery of chemosensitizers improve chemotherapy efficacy without incurring additional toxicity. 
  • Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity. 
  • Neuronal ceroid lipofuscinosis diagnosed via skin biopsy. 
  • Nitric oxide-mediated intracellular growth restriction of pathogenic Rhodococcus equi can be prevented by iron. 
  • Non-viral charge reversal vectors for pDNA delivery. 
  • Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity. 
  • PEGylated gold nanoparticles conjugated to monoclonal F19 antibodies as targeted labeling agents for human pancreatic carcinoma tissue. 
  • PRCD is essential for high-fidelity photoreceptor disc formation. 
  • Palladin is an actin cross-linking protein that uses immunoglobulin-like domains to bind filamentous actin. 
  • Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. 
  • Phytotoxicity of soluble graphitic nanofibers to model plant species. 
  • Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity. 
  • Protein- Polymer Nanoparticles for Nonviral Gene Delivery 
  • Quick-freeze/deep-etch electron microscopy visualization of the mouse posterior pole. 
  • Rational selection of gold nanorod geometry for label-free plasmonic biosensors. 
  • Reconfigurable core-satellite nanoassemblies as molecularly-driven plasmonic switches 
  • Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. 
  • Reducing liposome size with ultrasound: bimodal size distributions. 
  • Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b. 
  • Relation between the redox state of iron-based nanoparticles and their cytotoxicity toward Escherichia coli. 
  • Release of outer membrane vesicles by Gram-negative bacteria is a novel envelope stress response. 
  • Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction. 
  • Self-assembly of silver nanoparticles: synthesis, stabilization, optical properties, and application in surface-enhanced Raman scattering. 
  • Shape and size control of ZnO nanostructures via a simple solution route. 
  • Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation. 
  • Simple fixation and storage protocol for preserving the internal structure of intact human donor lenses and extracted human nuclear cataract specimens. 
  • Single-handed helical wrapping of single-walled carbon nanotubes by chiral, ionic, semiconducting polymers. 
  • Size-controlled dissolution of organic-coated silver nanoparticles. 
  • Speciation Matters: Bioavailability of Silver and Silver Sulfide Nanoparticles to Alfalfa (Medicago sativa). 
  • Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability. 
  • Sporangiospore size dimorphism is linked to virulence of Mucor circinelloides. 
  • Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost. 
  • Stimulation of Acanthamoeba actomyosin ATPase activity by myosin-II polymerization. 
  • Stream transport of iron and phosphorus by authigenic nanoparticles in the Southern Piedmont of the U.S. 
  • Sudden Unexpected Death in a Child From an Anaplastic Ependymoma. 
  • Sulfidation of silver nanowires inside human alveolar epithelial cells: a potential detoxification mechanism. 
  • Suppression of the NF-κB pathway by diesel exhaust particles impairs human antimycobacterial immunity. 
  • Surface loop dynamics in adeno-associated virus capsid assembly. 
  • Surfactant-assisted synthesis of Keggin-type polyoxometalates nanorods. 
  • Synaptic alterations at inner hair cells precede spiral ganglion cell loss in aging C57BL/6J mice. 
  • Synthesis, characterization, and bioavailability of mannosylated shell cross-linked nanoparticles. 
  • TAT peptide-functionalized gold nanostars: enhanced intracellular delivery and efficient NIR photothermal therapy using ultralow irradiance. 
  • TCDD disrupts hypural skeletogenesis during medaka embryonic development. 
  • Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia. 
  • Tat-functionalized near-infrared emissive polymersomes for dendritic cell labeling. 
  • Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. 
  • Tensile deformation of NiTi wires. 
  • The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity. 
  • The HO-1/CO system regulates mitochondrial-capillary density relationships in human skeletal muscle. 
  • The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. 
  • The control of mercury vapor using biotrickling filters. 
  • The stability of silver nanoparticles in a model of pulmonary surfactant. 
  • Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling. 
  • Transducin gamma-subunit sets expression levels of alpha- and beta-subunits and is crucial for rod viability. 
  • Tunable and amplified Raman gold nanoprobes for effective tracking (TARGET): in vivo sensing and imaging. 
  • Tuning the field-emission properties of tungsten oxide nanorods. 
  • Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. 
  • Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia. 
  • Ultrastructural development of the small intestinal mucosa in the embryo and turkey poult: A light and electron microscopy study. 
  • Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2). 
  • Understanding the role of oxidative etching in the polyol synthesis of Pd nanoparticles with uniform shape and size. 
  • Use of dominant-negative HrpA mutants to dissect Hrp pilus assembly and type III secretion in Pseudomonas syringae pv. tomato. 
  • VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations. 
  • α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration. 
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  Keywords of People

  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Taylor, Gregory Alan, Professor in Medicine, Integrative Immunobiology
  • Wax, Adam P., Professor of Biomedical Engineering, Biomedical Engineering