Thermoanaerobacter

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  Subject Areas on Research

  • Binding and signaling of surface-immobilized reagentless fluorescent biosensors derived from periplasmic binding proteins. 
  • Essential role of an active-site guanine in glmS ribozyme catalysis. 
  • Local encoding of computationally designed enzyme activity. 
  • Molecular biology. Versatility of self-cleaving ribozymes. 
  • Probing domain interactions in soluble guanylate cyclase. 
  • Requirement of helix P2.2 and nucleotide G1 for positioning the cleavage site and cofactor of the glmS ribozyme. 
  • Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure. 
  • The backbone structure of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein is essentially identical to its mesophilic E. coli homolog.