Tumor Burden

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  Subject Areas on Research

  • (18)F-Fluorothymidine PET-CT for resected malignant gliomas before radiotherapy: tumor extent according to proliferative activity compared with MRI. 
  • 18F-FDG PET/CT Metabolic Tumor Volume and Intratumoral Heterogeneity in Pancreatic Adenocarcinomas: Impact of Dual-Time Point and Segmentation Methods. 
  • 18F-FDG metabolic tumor volume and total glycolytic activity of oral cavity and oropharyngeal squamous cell cancer: adding value to clinical staging. 
  • 18F-FDG-PET/CT therapy assessment of locally advanced pancreatic adenocarcinoma: impact on management and utilization of quantitative parameters for patient survival prediction. 
  • 3'-Deoxy-3'-[F-18]fluorothymidine positron emission tomography in patients with recurrent glioblastoma multiforme: comparison with Gd-DTPA enhanced magnetic resonance imaging. 
  • 3D image guidance assisted identification of colorectal cancer liver metastases not seen on intraoperative ultrasound: results from a prospective trial. 
  • A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer. 
  • A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy. 
  • A comparison of two non-radioactive alternatives to wire for the localization of non-palpable breast cancers. 
  • A farewell to Barcelona Clinic Liver Cancer (BCLC) classification for hepatocellular carcinoma. 
  • A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice. 
  • A new treatment paradigm: neoadjuvant radiosurgery before surgical resection of brain metastases with analysis of local tumor recurrence. 
  • A novel method for volumetric MRI response assessment of enhancing brain tumors. 
  • A novel, reproducible, and objective method for volumetric magnetic resonance imaging assessment of enhancing glioblastoma. 
  • A prognostic volumetric threshold of gross tumor volume in head and neck cancer patients treated with radiotherapy. 
  • A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype. 
  • A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram. 
  • ACR appropriateness criteria on external beam radiation therapy treatment planning for clinically localized prostate cancer expert panel on radiation oncology--prostate. 
  • ASO Visual Abstract: Tumor Burden Dictates Prognosis Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma: A Tool to Guide Post-Resection Adjuvant Chemotherapy? 
  • Accelerating volumetric cine MRI (VC-MRI) using undersampling for real-time 3D target localization/tracking in radiation therapy: a feasibility study. 
  • Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer. 
  • Actual 10-Year Survivors After Resection of Hepatocellular Carcinoma. 
  • Adaptive replanning strategies accounting for shrinkage in head and neck IMRT. 
  • Adaptive stereotactic body radiation therapy planning for lung cancer. 
  • Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme. 
  • Adjunct endovascular interventions in carotid body tumors. 
  • Adrenal Imaging Features Predict Malignancy Better than Tumor Size. 
  • African-American men with low-grade prostate cancer have higher tumor burdens: results from the Duke Prostate Center. 
  • Agreement among RTOG sarcoma radiation oncologists in contouring suspicious peritumoral edema for preoperative radiation therapy of soft tissue sarcoma of the extremity. 
  • American Society of Radiation Oncology recommendations for documenting intensity-modulated radiation therapy treatments. 
  • An effective preoperative three-dimensional radiotherapy target volume for extremity soft tissue sarcoma and the effect of margin width on local control. 
  • An investigation of kV mini-GRID spatially fractionated radiation therapy: dosimetry and preclinical trial. 
  • Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial. 
  • Anatomic tumor location influences the success of contemporary limb-sparing surgery and radiation among adults with soft tissue sarcomas of the extremities. 
  • Angiotensin receptor signaling and prostate tumor growth in mice. 
  • Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia. 
  • Anterior gland focal cryoablation: proof-of-concept primary prostate cancer treatment in select men with localized anterior cancers detected by multi-parametric magnetic resonance imaging. 
  • Anti-tumor activity of a novel monoclonal antibody, NPC-1C, optimized for recognition of tumor antigen MUC5AC variant in preclinical models. 
  • Apparatus-dependent dosimetric differences in spine stereotactic body radiotherapy. 
  • Assessment of Treatment Response With Diffusion-Weighted MRI and Dynamic Contrast-Enhanced MRI in Patients With Early-Stage Breast Cancer Treated With Single-Dose Preoperative Radiotherapy: Initial Results. 
  • Assessment of circulating tumor cells (CTCs) in prostate cancer patients with low-volume tumors. 
  • Associations Between Prostate Volume and Oncologic Outcomes in Men Undergoing Focal Cryoablation of the Prostate. 
  • Associations of Video Head Impulse Test and Caloric Testing among Patients with Vestibular Schwannoma. 
  • Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor. 
  • Basic mechanisms of therapeutic resistance to radiation and chemotherapy in lung cancer. 
  • Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease. 
  • Benchmark Credentialing Results for NRG-BR001: The First National Cancer Institute-Sponsored Trial of Stereotactic Body Radiation Therapy for Multiple Metastases. 
  • Biomarkers of immunotherapy in urothelial and renal cell carcinoma: PD-L1, tumor mutational burden, and beyond. 
  • Biopsy accuracy in identifying unilateral prostate cancer depends on prostate weight. 
  • Biopsy first: Lessons learned from Cancer and Leukemia Group B (CALGB) 140503. 
  • Bridging the translational gap: Implementation of multimodal small animal imaging strategies for tumor burden assessment in a co-clinical trial. 
  • Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression. 
  • Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells. 
  • Challenges in the clinical application of advanced technologies to reduce radiation-associated normal tissue injury. 
  • Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survival. 
  • Characterization of Small (< 4 cm) Focal Renal Lesions: Diagnostic Accuracy of Spectral Analysis Using Single-Phase Contrast-Enhanced Dual-Energy CT. 
  • Characterization of tumor mutation burden, PD-L1 and DNA repair genes to assess relationship to immune checkpoint inhibitors response in metastatic renal cell carcinoma. 
  • Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface. 
  • Chemotherapy-related amenorrhea after adjuvant paclitaxel-trastuzumab (APT trial). 
  • Clinical end points and response criteria in mycosis fungoides and Sézary syndrome: a consensus statement of the International Society for Cutaneous Lymphomas, the United States Cutaneous Lymphoma Consortium, and the Cutaneous Lymphoma Task Force of the European Organisation for Research and Treatment of Cancer. 
  • Clinical implications of phosphorylated STAT3 expression in De Novo diffuse large B-cell lymphoma. 
  • Clinical practice guidance for radiotherapy planning after induction chemotherapy in locoregionally advanced head-and-neck cancer. 
  • Clinical predictors of renal mass pathological features. 
  • Clinicopathological Features and Prognosis of Mixed-Type T1a Gastric Cancer Based on Lauren's Classification. 
  • Clinicopathological features to distinguish malignant solitary fibrous tumors of the prostate from prostatic stromal tumors. 
  • Colorectal cancer with potentially resectable hepatic metastases: optimizing treatment. 
  • Combined ablation and resection (CARe) as an effective parenchymal sparing treatment for extensive colorectal liver metastases. 
  • Computed tomography imaging of primary lung cancer in mice using a liposomal-iodinated contrast agent. 
  • Computer-extracted MR imaging features are associated with survival in glioblastoma patients. 
  • Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer. 
  • Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: a prospective trial. 
  • Cone-beam CT localization of internal target volumes for stereotactic body radiotherapy of lung lesions. 
  • Contemporary Multi-Institutional Cohort of 550 Cases of Phyllodes Tumors (2007-2017) Demonstrates a Need for More Individualized Margin Guidelines. 
  • Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma. 
  • Cost Implications of an Evidence-Based Approach to Radiation Treatment After Lumpectomy for Early-Stage Breast Cancer. 
  • Cryoablation for Small Renal Masses: Selection Criteria, Complications, and Functional and Oncologic Results. 
  • Current Approaches in the Management of Hepatic Adenomas. 
  • Data analysis: evaluation of nanoscale contrast agent enhanced CT scan to differentiate between benign and malignant lung cancer in mouse model. 
  • Defective antitumor responses in CX3CR1-deficient mice. 
  • Defining the chance of cure after resection for hepatocellular carcinoma within and beyond the Barcelona Clinic Liver Cancer guidelines: A multi-institutional analysis of 1,010 patients. 
  • Defining the optimal planning target volume in image-guided stereotactic radiosurgery of brain metastases: results of a randomized trial. 
  • Delayed-Phase Enhancement for Evaluation of Malignant Pleural Mesothelioma on Computed Tomography: A Prospective Cohort Study. 
  • Development of RTOG consensus guidelines for the definition of the clinical target volume for postoperative conformal radiation therapy for prostate cancer. 
  • Development of enhanced ethanol ablation as an alternative to surgery in treatment of superficial solid tumors. 
  • Differential platelet levels affect response to taxane-based therapy in ovarian cancer. 
  • Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. 
  • Does larger tumor volume explain the higher prostate specific antigen levels in black men with prostate cancer--Results from the SEARCH database. 
  • Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer. 
  • Dose as a function of lung volume and planned treatment volume in helical tomotherapy intensity-modulated radiation therapy-based stereotactic body radiation therapy for small lung tumors. 
  • Dose de-escalation with gamma knife radiosurgery in the treatment of choroidal melanoma. 
  • Dosimetric effect of intrafraction motion and residual setup error for hypofractionated prostate intensity-modulated radiotherapy with online cone beam computed tomography image guidance. 
  • Dosimetric quantifiers for low-dose-rate prostate brachytherapy: is V(100) superior to D(90)? 
  • Dosimetric verification of lung cancer treatment using the CBCTs estimated from limited-angle on-board projections. 
  • Dual-Energy CT Vital Iodine Tumor Burden for Response Assessment in Patients With Metastatic GIST Undergoing TKI Therapy: Comparison With Standard CT and FDG PET/CT Criteria. 
  • Dual-energy micro-CT functional imaging of primary lung cancer in mice using gold and iodine nanoparticle contrast agents: a validation study. 
  • Dual-energy micro-computed tomography imaging of radiation-induced vascular changes in primary mouse sarcomas. 
  • ELF3 is a repressor of androgen receptor action in prostate cancer cells. 
  • Early 18F-FDG-PET Response During Radiation Therapy for HPV-Related Oropharyngeal Cancer May Predict Disease Recurrence. 
  • Early Reduction in ctDNA Predicts Survival in Patients with Lung and Bladder Cancer Treated with Durvalumab. 
  • Effect of pazopanib on tumor microenvironment and liposome delivery. 
  • Effects of Cancer Stage and Treatment Differences on Racial Disparities in Survival From Colon Cancer: A United States Population-Based Study. 
  • Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models. 
  • Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size. 
  • Evaluating changes in radiation treatment volumes from post-operative to same-day planning MRI in High-grade gliomas. 
  • Evaluating the validity of model for end-stage liver disease exception points for hepatocellular carcinoma patients with multiple nodules <2 cm. 
  • Evaluation of the accuracy of a 3D surface imaging system for patient setup in head and neck cancer radiotherapy. 
  • Evaluation of the effect of transcytolemmal water exchange analysis for therapeutic response assessment using DCE-MRI: a comparison study. 
  • Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model. 
  • Exploring the Margin Recipe for Online Adaptive Radiation Therapy for Intermediate-Risk Prostate Cancer: An Intrafractional Seminal Vesicles Motion Analysis. 
  • FDG Avidity and Tumor Burden: Survival Outcomes for Patients With Recurrent Breast Cancer. 
  • FDG PET metabolic tumor volume segmentation and pathologic volume of primary human solid tumors. 
  • FDG PET/CT in the management of primary pleural tumors and pleural metastases. 
  • FOLFIRINOX Induction Therapy for Stage 3 Pancreatic Adenocarcinoma. 
  • FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate. 
  • Factors Associated with Recurrence Rates and Long-Term Survival in Women Diagnosed with Breast Cancer Ages 40 and Younger. 
  • Factors predicting prostatic biopsy Gleason sum under grading. 
  • Fibrosarcoma-like lipomatous neoplasm: a reappraisal of so-called spindle cell liposarcoma defining a unique lipomatous tumor unrelated to other liposarcomas. 
  • Fish oil slows prostate cancer xenograft growth relative to other dietary fats and is associated with decreased mitochondrial and insulin pathway gene expression. 
  • Fluorodeoxyglucose-positron-emission tomography imaging of head and neck squamous cell cancer. 
  • Functional Implications of Renal Tumor Enucleation Relative to Standard Partial Nephrectomy. 
  • GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs". 
  • Genetic And Morphological Evaluation (GAME) score for patients with colorectal liver metastases. 
  • Genetic variants at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 
  • Global search for chromosomal abnormalities in infiltrating ductal carcinoma of the breast using array-comparative genomic hybridization. 
  • Gut barrier dysfunction in the Apc(Min/+) mouse model of colon cancer cachexia. 
  • Head and neck squamous cell cancer (stages III and IV) induction chemotherapy assessment: value of FDG volumetric imaging parameters. 
  • Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth. 
  • Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer. 
  • Helical IMRT-Based Stereotactic Body Radiation Therapy Using an Abdominal Compression Technique and Modified Fractionation Regimen for Small Hepatocellular Carcinoma. 
  • High-fructose corn syrup enhances intestinal tumor growth in mice. 
  • Image acquisition optimization of a limited-angle intrafraction verification (LIVE) system for lung radiotherapy. 
  • Imaging primary lung cancers in mice to study radiation biology. 
  • Impact of T status and N status on perioperative outcomes after thoracoscopic lobectomy for lung cancer. 
  • Impact of collimator leaf width and treatment technique on stereotactic radiosurgery and radiotherapy plans for intra- and extracranial lesions. 
  • Impact of consolidation radiation therapy in stage III-IV diffuse large B-cell lymphoma with negative post-chemotherapy radiologic imaging. 
  • In Reply to O'Sullivan et al. 
  • In-bore magnetic resonance-guided transrectal biopsy for the detection of clinically significant prostate cancer. 
  • Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program. 
  • Initial testing of the replication competent Seneca Valley virus (NTX-010) by the pediatric preclinical testing program. 
  • International Multicenter Experience of Isolated Limb Infusion for In-Transit Melanoma Metastases in Octogenarian and Nonagenarian Patients. 
  • Interreader agreement and variability of FDG PET volumetric parameters in human solid tumors. 
  • Intra-reader reliability of FDG PET volumetric tumor parameters: effects of primary tumor size and segmentation methods. 
  • Intra-tumor molecular heterogeneity in breast cancer: definitions of measures and association with distant recurrence-free survival. 
  • Intraductal Oncocytic Papillary Neoplasms: Clinical-Pathologic Characterization of 24 Cases, With An Emphasis on Associated Invasive Carcinomas. 
  • Intraoperative mapping during repeat awake craniotomy reveals the functional plasticity of adult cortex. 
  • Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins? 
  • Is tumor response important for renal carcinoma? 
  • JOURNAL CLUB: Value of Quantitative FDG PET/CT Volumetric Biomarkers in Recurrent Colorectal Cancer Patient Survival. 
  • Liver Transplantation Outcomes in a U.S. Multicenter Cohort of 789 Patients With Hepatocellular Carcinoma Presenting Beyond Milan Criteria. 
  • Local excision results in comparable survival to radical resection for early-stage rectal carcinoid. 
  • Localized malignant mesothelioma, an unusual and poorly characterized neoplasm of serosal origin: best current evidence from the literature and the International Mesothelioma Panel. 
  • Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway. 
  • Low-carbohydrate diets and prostate cancer: how low is "low enough"? 
  • Lung Cancer Screening, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology. 
  • Management of hepatocellular adenoma: comparison of resection, embolization and observation. 
  • Mechanical Signaling and Extracellular Matrix in Uterine Fibroids. 
  • Metabolomics of human cerebrospinal fluid identifies signatures of malignant glioma. 
  • Minimally invasive gastrectomy for gastric cancer: A national perspective on oncologic outcomes and overall survival. 
  • Modeling pathologic response of esophageal cancer to chemoradiation therapy using spatial-temporal 18F-FDG PET features, clinical parameters, and demographics. 
  • Modulation of pancreatic cancer chemoresistance by inhibition of TAK1. 
  • Multi-institution prospective trial of reduced-dose craniospinal irradiation (23.4 Gy) followed by conformal posterior fossa (36 Gy) and primary site irradiation (55.8 Gy) and dose-intensive chemotherapy for average-risk medulloblastoma. 
  • Multifocality and prostate cancer detection by multiparametric magnetic resonance imaging: correlation with whole-mount histopathology. 
  • Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma. 
  • Mutational Analysis of Patients With Colorectal Cancer in CALGB/SWOG 80405 Identifies New Roles of Microsatellite Instability and Tumor Mutational Burden for Patient Outcome. 
  • NCCN Guidelines Insights: Uveal Melanoma, Version 1.2019. 
  • Nanoshells for photothermal cancer therapy. 
  • Neoadjuvant Systemic Therapy for Breast Cancer: Factors Influencing Surgeons' Referrals. 
  • Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. 
  • Notch promotes radioresistance of glioma stem cells. 
  • Notch3 pathway alterations in ovarian cancer. 
  • Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling axis for potent tumorigenic activity. 
  • Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. 
  • Organs at Risk Considerations for Thoracic Stereotactic Body Radiation Therapy: What Is Safe for Lung Parenchyma? 
  • Overall Tumor Burden Dictates Outcomes for Patients Undergoing Resection of Multinodular Hepatocellular Carcinoma Beyond the Milan Criteria. 
  • PET-based primary tumor volumetric parameters and survival of patients with non-small cell lung carcinoma. 
  • PI3K/mTOR Dual Inhibitor, LY3023414, Demonstrates Potent Antitumor Efficacy Against Esophageal Adenocarcinoma in a Rat Model. 
  • Pancreatic neuroendocrine tumors with involved surgical margins: prognostic factors and the role of adjuvant radiotherapy. 
  • Parenchymal-Sparing Versus Anatomic Liver Resection for Colorectal Liver Metastases: a Systematic Review. 
  • Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the US Multicenter HCC Transplant Consortium. 
  • Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. 
  • Pathologic grade and tumor size are associated with recurrence-free survival in patients with duodenal neuroendocrine tumors. 
  • Pembrolizumab in Patients With Metastatic Breast Cancer With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study. 
  • Percent tumor involvement and risk of biochemical progression after radical prostatectomy. 
  • Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth. 
  • Perineural and intraneural invasion in posttherapy pancreaticoduodenectomy specimens predicts poor prognosis in patients with pancreatic ductal adenocarcinoma. 
  • Persistent pulmonary subsolid nodules with solid portions of 5 mm or smaller: Their natural course and predictors of interval growth. 
  • Phase II study of neoadjuvant bevacizumab and radiotherapy for resectable soft tissue sarcomas. 
  • Phase III study of pasireotide long-acting release in patients with metastatic neuroendocrine tumors and carcinoid symptoms refractory to available somatostatin analogues. 
  • Preclinical Modeling of Surgery and Steroid Therapy for Glioblastoma Reveals Changes in Immunophenotype that are Associated with Tumor Growth and Outcome. 
  • Predictors of Ultrasound Failure to Detect Hepatocellular Carcinoma. 
  • Pregnancy-related fibroid reduction. 
  • Preoperative single fraction partial breast radiotherapy for early-stage breast cancer. 
  • Prevalence and clinical implications of epstein-barr virus infection in de novo diffuse large B-cell lymphoma in Western countries. 
  • Primary tumour standardised uptake value is prognostic in nonsmall cell lung cancer: a multivariate pooled analysis of individual data. 
  • Progesterone promotes immunomodulation and tumor development in the murine mammary gland. 
  • Prognostic Value of FDG PET/CT-Derived Parameters in Pancreatic Adenocarcinoma at Initial PET/CT Staging. 
  • Prognostic modeling for patients with colorectal liver metastases incorporating FDG PET radiomic features. 
  • Prognostic value of FDG PET metabolic tumor volume in human papillomavirus-positive stage III and IV oropharyngeal squamous cell carcinoma. 
  • Prognostic value of midtreatment FDG-PET in oropharyngeal cancer. 
  • Progression Patterns in the Remnant Pancreas after Resection of Non-Invasive or Micro-Invasive Intraductal Papillary Mucinous Neoplasms (IPMN). 
  • Pseudo-CT generation from multi-parametric MRI using a novel multi-channel multi-path conditional generative adversarial network for nasopharyngeal carcinoma patients. 
  • Pulmonary Granular Cell Tumors: A Study of 4 Cases Including a Malignant Phenotype. 
  • Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes. 
  • Quantification and minimization of uncertainties of internal target volume for stereotactic body radiation therapy of lung cancer. 
  • Quantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor Trial. 
  • RAS mutations in thyroid FNA specimens are highly predictive of predominantly low-risk follicular-pattern cancers. 
  • RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer. 
  • RTOG sarcoma radiation oncologists reach consensus on gross tumor volume and clinical target volume on computed tomographic images for preoperative radiotherapy of primary soft tissue sarcoma of extremity in Radiation Therapy Oncology Group studies. 
  • Race-associated biological differences among Luminal A breast tumors. 
  • Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study. 
  • Racial variation in adjuvant chemotherapy initiation among breast cancer patients receiving oncotype DX testing. 
  • Radiofrequency Ablation Duration per Tumor Volume May Correlate with Overall Survival in Solitary Hepatocellular Carcinoma Patients Treated with Radiofrequency Ablation Plus Lyso-Thermosensitive Liposomal Doxorubicin. 
  • Radiogenomics of lower-grade glioma: algorithmically-assessed tumor shape is associated with tumor genomic subtypes and patient outcomes in a multi-institutional study with The Cancer Genome Atlas data. 
  • Rare codons capacitate Kras-driven de novo tumorigenesis. 
  • Recurrence and Survival After Resection of Small Intraductal Papillary Mucinous Neoplasm-associated Carcinomas (≤20-mm Invasive Component): A Multi-institutional Analysis. 
  • Reduced Core Targeted (RCT) biopsy: Combining multiparametric magnetic resonance imaging - transrectal ultrasound fusion targeted biopsy with laterally-directed sextant biopsies - An alternative template for prostate fusion biopsy. 
  • Reduction in Tumor Volume by Cone Beam Computed Tomography Predicts Overall Survival in Non-Small Cell Lung Cancer Treated With Chemoradiation Therapy. 
  • Repeatability of Automated Image Segmentation with BraTumIA in Patients with Recurrent Glioblastoma. 
  • Reproducibility of tumor motion probability distribution function in stereotactic body radiation therapy of lung cancer. 
  • Resection and survival. 
  • Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies. 
  • Role of postmastectomy radiation after neoadjuvant chemotherapy in stage II-III breast cancer. 
  • STING suppresses bone cancer pain via immune and neuronal modulation. 
  • Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month, placebo-controlled, randomized trials. 
  • Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma. 
  • Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis. 
  • Serial Endoscopic Evaluation of Esophageal Disease in a Cancer Model: A Paradigm Shift for Esophageal Adenocarcinoma (EAC) Drug Discovery and Development. 
  • Serum soluble mesothelin-related protein (SMRP) and fibulin-3 levels correlate with baseline malignant pleural mesothelioma (MPM) tumor volumes but are not useful as biomarkers of response in an immunotherapy trial. 
  • Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer. 
  • Significant Reduction of Late Toxicities in Patients With Extremity Sarcoma Treated With Image-Guided Radiation Therapy to a Reduced Target Volume: Results of Radiation Therapy Oncology Group RTOG-0630 Trial. 
  • Simultaneous in vivo optical quantification of key metabolic and vascular endpoints reveals tumor metabolic diversity in murine breast tumor models. 
  • Soft Tissue Sarcoma of the Extremities: What Is the Value of Treating at High-volume Centers? 
  • Solid pseudopapillary neoplasm of the pancreas: clinicopathologic and survival analyses of 64 cases from a single institution. 
  • Sorafenib, a multikinase inhibitor, enhances the response of melanoma to regional chemotherapy. 
  • Stage 1 testing and pharmacodynamic evaluation of the HSP90 inhibitor alvespimycin (17-DMAG, KOS-1022) by the pediatric preclinical testing program. 
  • Stereotactic body radiotherapy for lesions of the spine and paraspinal regions. 
  • Superior prognostic utility of gross and metabolic tumor volume compared to standardized uptake value using PET/CT in head and neck squamous cell carcinoma patients treated with intensity-modulated radiotherapy. 
  • Suppression of isoprenylcysteine carboxylmethyltransferase compromises DNA damage repair. 
  • Surveillance after prostate focal therapy. 
  • Systemic anti-tumour effects of local thermally sensitive liposome therapy. 
  • TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. 
  • Targeting eNOS in pancreatic cancer. 
  • Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis) by inhibiting hedgehog signaling. 
  • Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program. 
  • The Effect of Tumor Size and Histologic Findings on Outcomes After Segmentectomy vs Lobectomy for Clinically Node-Negative Non-Small Cell Lung Cancer. 
  • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. 
  • The PREVAIL Study: Primary Outcomes by Site and Extent of Baseline Disease for Enzalutamide-treated Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer. 
  • The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer. 
  • The immune profile of small HER2-positive breast cancers: a secondary analysis from the APT trial. 
  • The impact of tumor size on the association of the extent of lymph node resection and survival in clinical stage I non-small cell lung cancer. 
  • The influence of diabetes severity on receipt of guideline-concordant treatment for breast cancer. 
  • The mRECIST Classification Provides Insight into Tumor Biology for Patients With Hepatocellular Carcinoma Awaiting Liver Transplantation. 
  • The oligometastatic state - separating truth from wishful thinking. 
  • The oncogenomic function of androgen receptor in esophageal squamous cell carcinoma is directed by GATA3. 
  • The role of seminal vesicle motion in target margin assessment for online image-guided radiotherapy for prostate cancer. 
  • The small abnormal parathyroid gland is increasingly common and heralds operative complexity. 
  • The state of prostate MRI in 2013. 
  • Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. 
  • Thermal dose fractionation affects tumour physiological response. 
  • Three-dimensional Radiologic Assessment of Chemotherapy Response in Ewing Sarcoma Can Be Used to Predict Clinical Outcome. 
  • Tissue clearing techniques for three-dimensional optical imaging of intact human prostate and correlations with multi-parametric MRI. 
  • Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study. 
  • Trends in the risk and burden of second primary malignancy among survivors of smoking-related cancers in the United States. 
  • Triphasic contrast enhanced CT simulation with bolus tracking for pancreas SBRT target delineation. 
  • Tumor Burden Dictates Prognosis Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma: A Tool to Guide Post-Resection Adjuvant Chemotherapy? 
  • Tumor Mutational Burden as a Predictor of Immunotherapy Response: Is More Always Better? 
  • Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. 
  • Tumor volume changes on 1.5 tesla endorectal MRI during neoadjuvant androgen suppression therapy for higher-risk prostate cancer and recurrence in men treated using radiation therapy results of the phase II CALGB 9682 study. 
  • Understanding the pathological features of focality, grade and tumour volume of early-stage prostate cancer as a foundation for parenchyma-sparing prostate cancer therapies: active surveillance and focal targeted therapy. 
  • Upfront Magnetic Resonance Imaging-Guided Stereotactic Laser-Ablation in Newly Diagnosed Glioblastoma: A Multicenter Review of Survival Outcomes Compared to a Matched Cohort of Biopsy-Only Patients. 
  • Urinary aquaporin 1 and perilipin 2: Can these novel markers accurately characterize small renal masses and help guide patient management? 
  • Urinary concentrations of aquaporin-1 and perilipin-2 in patients with renal cell carcinoma correlate with tumor size and stage but not grade. 
  • Use of bioluminescence imaging to detect enhanced hepatic and systemic tumor growth following partial hepatectomy in mice. 
  • Utilizing 18F-fluoroethyltyrosine (FET) positron emission tomography (PET) to define suspected nonenhancing tumor for radiation therapy planning of glioblastoma. 
  • Utilizing Machine Learning for Pre- and Postoperative Assessment of Patients Undergoing Resection for BCLC-0, A and B Hepatocellular Carcinoma: Implications for Resection Beyond the BCLC Guidelines. 
  • Uveal melanoma treated with iodine-125 episcleral plaque: an analysis of dose on disease control and visual outcomes. 
  • Validating a prognostic scoring system for postmastectomy locoregional recurrence in breast cancer. 
  • Value of Intratumoral Metabolic Heterogeneity and Quantitative 18F-FDG PET/CT Parameters in Predicting Prognosis for Patients With Cervical Cancer. 
  • Variation in the definition of clinical target volumes for pelvic nodal conformal radiation therapy for prostate cancer. 
  • Variation in the gross tumor volume and clinical target volume for preoperative radiotherapy of primary large high-grade soft tissue sarcoma of the extremity among RTOG sarcoma radiation oncologists. 
  • Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression. 
  • Vascular inflow control during hemi-hepatectomy: a comparison between intrahepatic pedicle ligation and extrahepatic vascular ligation. 
  • Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma. 
  • Widespread organ tolerance to Xist loss and X reactivation except under chronic stress in the gut. 
  • Will AI Improve Tumor Delineation Accuracy for Radiation Therapy? 
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  Keywords of People

  • Badea, Cristian Tudorel, Professor in Radiology, Biomedical Engineering
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Craciunescu, Oana, Professor of Radiation Oncology, Radiation Oncology
  • Johnson, G. Allan, Charles E. Putman University Distinguished Professor of Radiology, Biomedical Engineering
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Pharmacology & Cancer Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Yoo, Sua, Associate Professor of Radiation Oncology, Radiation Oncology