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Subject Areas on Research
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A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene.
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Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust.
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Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice.
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Antifibrotic therapies: will we ever get there?
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Body mass index and obesity- and diabetes-associated genotypes and risk for pancreatic cancer.
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CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice.
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CD10 marks non-canonical PPARγ-independent adipocyte maturation and browning potential of adipose-derived stem cells.
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Characterization of adipogenic, PPARγ, and TRβ activities in house dust extracts and their associations with organic contaminants.
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Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust.
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Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
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De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity.
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Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity.
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Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus.
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Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos.
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Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation.
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Effect-Directed Analysis of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) Ligands in Indoor Dust.
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Farglitazar lacks antifibrotic activity in patients with chronic hepatitis C infection.
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From Prescription to Transcription: Genome Sequence as Drug Target.
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GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain.
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Genetic variants in peroxisome proliferator-activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population.
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Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.
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In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components.
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Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.
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Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.
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Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro.
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Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients.
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Mouse adenovirus type 1 infection of adipose tissue.
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MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet.
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Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet.
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Noncanonical agonist PPARγ ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy.
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Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.
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Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio).
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PAX8/PPARγ rearrangement in thyroid nodules predicts follicular-pattern carcinomas, in particular the encapsulated follicular variant of papillary carcinoma.
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PPARgamma agonists follow an unknown TRAIL in lung cancer.
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PPARgamma agonists prevent TGFbeta1/Smad3-signaling in human hepatic stellate cells.
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Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization.
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Peroxisome Proliferator-Activated Receptor γ and Its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization.
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Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter.
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Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction.
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Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice.
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Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes.
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Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.
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Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin.
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Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.
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Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain).
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Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo.
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The differential effects of angiotensin II type 1 receptor blockers on microalbuminuria in relation to low-grade inflammation in metabolic hypertensive patients.
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The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster.
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The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells.
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The nuclear receptor-coactivator interaction surface as a target for peptide antagonists of the peroxisome proliferator-activated receptors.
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Thiazolidinediones and risk for atherosclerosis: pleiotropic effects of PPar gamma agonism.
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Thiazolidinediones, peripheral oedema and congestive heart failure: what is the evidence?
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Transcriptional control of preadipocyte determination by Zfp423.
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Transgenic ω-3 PUFA enrichment alters morphology and gene expression profile in adipose tissue of obese mice: Potential role for protectins.
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Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor.
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Unconventional oil and gas chemicals and wastewater-impacted water samples promote adipogenesis via PPARγ-dependent and independent mechanisms in 3T3-L1 cells.
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Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-γ-Dependent Manner.
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ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes.
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p38γ activity is required for maintenance of slow skeletal muscle size.
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Keywords of People