Receptors, Tumor Necrosis Factor, Type I
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Subject Areas on Research
- A Randomized Dose-Escalation Study of the Safety and Anti-Inflammatory Activity of the p38 Mitogen-Activated Protein Kinase Inhibitor Dilmapimod in Severe Trauma Subjects at Risk for Acute Respiratory Distress Syndrome.
- A boy with fever and whorl keratopathy.
- A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes.
- A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling.
- A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses.
- Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.
- Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors.
- Apoptosis and NF-kappa B: the FADD connection.
- Blockade of tissue factor: treatment for organ injury in established sepsis.
- CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival.
- CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control.
- CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis.
- Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1.
- Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.
- Effects of Combined Tristetraprolin/Tumor Necrosis Factor Receptor Deficiency on the Splenic Transcriptome.
- Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature.
- Expression of tumor necrosis factor receptor-1 in arterial wall cells promotes atherosclerosis.
- G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors.
- Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production.
- Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer's disease.
- Induction of apoptosis in vascular smooth muscle cells by mechanical stretch.
- Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression.
- Inflammatory biomarkers in heart failure.
- Interferon regulatory factor-1-induced apoptosis mediated by a ligand-independent fas-associated death domain pathway in breast cancer cells.
- JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain.
- Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death.
- NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.
- Phosphorylation of tumor necrosis factor receptor 1 (p55) protects macrophages from silica-induced apoptosis.
- Poxvirus tumor necrosis factor receptor (TNFR)-like T2 proteins contain a conserved preligand assembly domain that inhibits cellular TNFR1-induced cell death.
- Prognostic significance of biomarkers in predicting outcome in patients with coronary artery disease and left ventricular dysfunction: results of the biomarker substudy of the Surgical Treatment for Ischemic Heart Failure trials.
- Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy.
- Pulmonary toxicity of induction chemotherapy prior to standard or high-dose chemotherapy with autologous hematopoietic support.
- Release of nonmuscle myosin II from the cytosolic domain of tumor necrosis factor receptor 2 is required for target gene expression.
- Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.
- Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer.
- Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor α.
- Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.
- Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1.
- TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2.
- TNF-α/TNFR1 Signaling is Required for the Full Expression of Acute and Chronic Itch in Mice via Peripheral and Central Mechanisms.
- Tumor necrosis factor alpha (TNF alpha)-induced ICAM-1 surface expression in airway epithelial cells in vitro: possible signal transduction mechanisms.
- Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia.
- USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis.
- Use of tumor necrosis factor inhibitors in uveitis.
- Using multimarker screening to identify biomarkers associated with cardiovascular death in patients with atrial fibrillation.
- Utilizing an interim futility analysis of the OVAL study (VB-111-701/GOG 3018) for potential reduction of risk: A phase III, double blind, randomized controlled trial of ofranergene obadenovec (VB-111) and weekly paclitaxel in patients with platinum resistant ovarian cancer.
- Vein graft neointimal hyperplasia is exacerbated by tumor necrosis factor receptor-1 signaling in graft-intrinsic cells.
- c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.