Premature Birth

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  Subject Areas on Research

  • 17-OHPC to Prevent Recurrent Preterm Birth in Singleton Gestations (PROLONG Study): A Multicenter, International, Randomized Double-Blind Trial. 
  • 17-hydroxyprogesterone caproate for women with congenital uterine anomalies: does it impact the risk of recurrent preterm birth? 
  • A Prematurity Collaborative Birth Equity Consensus Statement for Mothers and Babies. 
  • A Spatial Measure of Neighborhood Level Racial Isolation Applied to Low Birthweight, Preterm Birth, and Birthweight in North Carolina 
  • A prospective study of the association between vigorous physical activity during pregnancy and length of gestation and birthweight. 
  • A systematic review of evidence for maternal preconception exposure to outdoor air pollution on Children's health. 
  • A time-series analysis of air pollution and preterm birth in Pennsylvania, 1997-2001. 
  • ACC-AHA Diagnostic Criteria for Hypertension in Pregnancy Identifies Patients at Intermediate Risk of Adverse Outcomes. 
  • Absence of mitochondrial progesterone receptor polymorphisms in women with spontaneous preterm birth. 
  • Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth. 
  • Adverse birth outcomes among nulliparous vs. multiparous women. 
  • Alteration in vaginal microflora, douching prior to pregnancy, and preterm birth. 
  • An Observational Study on Early Dyadic Interactive Behaviors of Mothers With Early-Preterm, Late-Preterm, and Full-Term Infants in Malawi. 
  • Antirheumatic medications in pregnancy and breastfeeding. 
  • Assessing Disparity Using Measures of Racial and Educational Isolation. 
  • Assessment of Psychosocial and Neonatal Risk Factors for Trajectories of Behavioral Dysregulation Among Young Children From 18 to 72 Months of Age. 
  • Assessment of an Updated Neonatal Research Network Extremely Preterm Birth Outcome Model in the Vermont Oxford Network. 
  • Assessment of perinatal outcomes of pregnant women with severe versus simple malaria. 
  • Assisted reproductive technology and association with childhood cancer subtypes. 
  • Association Between Features of Spontaneous Late Preterm Labor and Late Preterm Birth. 
  • Association Between Maternal Obesity and Group B Streptococcus Colonization in a National U.S. Cohort. 
  • Association of 17α-Hydroxyprogesterone Caproate and Risk of Infection. 
  • Association of Prenatal Care Expansion With Use of Antidiabetic Agents During Pregnancies Among Latina Emergency Medicaid Recipients With Gestational Diabetes. 
  • Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth. 
  • Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis. 
  • Association of preterm birth with long-term survival, reproduction, and next-generation preterm birth. 
  • Associations between unstable housing, obstetric outcomes, and perinatal health care utilization. 
  • Bad bugs: antibiotic-resistant bacteriuria in pregnancy and risk of pyelonephritis. 
  • Bayesian isotonic regression and trend analysis. 
  • Behavioral influences on preterm birth: integrated analysis of the pregnancy, infection, and nutrition study. 
  • Beyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention. 
  • Bias from Differential Exposure Measurement Error in a Study of Flight Attendants. 
  • Birth Weight and Preterm Delivery Outcomes of Perinatally vs Nonperinatally Human Immunodeficiency Virus-Infected Pregnant Women in the United States: Results From the PHACS SMARTT Study and IMPAACT P1025 Protocol. 
  • Buprenorphine compared with methadone to treat pregnant women with opioid use disorder: a systematic review and meta-analysis of safety in the mother, fetus and child. 
  • Caffeine exposure and acute kidney injury in premature infants with necrotizing enterocolitis and spontaneous intestinal perforation. 
  • Cervical Cerclage versus Vaginal Progesterone for Management of Short Cervix in Low-Risk Women. 
  • Cervical dilation as a predictor of pregnancy outcome following emergency cerclage. 
  • Chorioamnionitis and Infectious Complications after Vaginal Delivery. 
  • Chronic prenatal depression and neonatal outcome. 
  • Clinical and economic evaluation of a proteomic biomarker preterm birth risk predictor: cost-effectiveness modeling of prenatal interventions applied to predicted higher-risk pregnancies within a large and diverse cohort. 
  • Clinical characteristics and response to prophylactic fluconazole of preterm VLBW neonates with baseline and acquired fungal colonisation in NICU: data from a multicentre RCT. 
  • Commentary on 'How often are late preterm births the result of non-evidence based practices: analysis from a retrospective cohort study at two tertiary referral centres in a nationalised healthcare system'. 
  • Comorbid depression and anxiety effects on pregnancy and neonatal outcome. 
  • Composition of fine particulate matter and risk of preterm birth: A nationwide birth cohort study in 336 Chinese cities. 
  • Confronting antimicrobial resistance together. 
  • Congenital Heart Disease in Premature Infants 25-32 Weeks' Gestational Age. 
  • Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population. 
  • Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery: A Secondary Analysis of a Randomized Clinical Trial. 
  • DNA methylation at imprint regulatory regions in preterm birth and infection. 
  • DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function. 
  • Delivery risks and outcomes associated with grand multiparity. 
  • Demographic, clinical and occupational characteristics associated with early onset of delivery: findings from the Duke Health and Safety Surveillance System, 2001-2004. 
  • Designing a tablet-based prematurity education app for parents hospitalized for preterm birth. 
  • Discordance in Antenatal Corticosteroid Use and Resuscitation Following Extremely Preterm Birth. 
  • Disease Severity and Perinatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 (COVID-19). 
  • Disparities in maternal hypertension and pregnancy outcomes: evidence from North Carolina, 1994-2003. 
  • Disparities in the use of antenatal corticosteroids among women with hypertension in North Carolina. 
  • Donor oocytes are associated with preterm birth when compared to fresh autologous in vitro fertilization cycles in singleton pregnancies. 
  • Doula Care: A Review of Outcomes and Impact on Birth Experience. 
  • Dynamics of human foveal development after premature birth. 
  • Early Life Characteristics and Neurodevelopmental Phenotypes in the Mount Sinai Children's Environmental Health Center. 
  • Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study. 
  • Effect of Cord Blood Magnesium Level at Birth on Non-neurologic Neonatal Outcomes. 
  • Effect of aspirin response signature gene expression on preterm birth and preeclampsia among women with lupus: a pilot study. 
  • Effective questionnaire design: How to use cognitive interviews to refine questionnaire items. 
  • Effectiveness of assisted reproductive technology (ART). 
  • Electroencephalography measures of relative power and coherence as reaching skill emerges in infants born preterm. 
  • Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature. 
  • EngagINg the COmmunity to Reduce Preterm birth via Adherence To an Individualized Prematurity Prevention Plan (INCORPorATe IP3): intervention development and future pilot study design. 
  • Estimation of shear wave speed in the human uterine cervix. 
  • Evaluation of Hypoglycemia in Neonates of Women at Risk for Late Preterm Delivery: An Antenatal Late Preterm Steroids Trial Cohort Study. 
  • Exercise and pregnancy outcome among urban, low-income, black women. 
  • Exploratory quantile regression with many covariates: An application to adverse birth outcomes 
  • Factors Associated with Previable Delivery following Second Trimester Rupture of Membranes. 
  • Factors Associated with Utilization of 17-Hydroxyprogesterone Caproate for the Prevention of Recurrent Preterm Birth. 
  • Factors that influence the timing of spontaneous labor at term. 
  • Faulty interpretation of observed racial disparity in recurrent preterm birth 
  • Financial stress as a mediator of the association between maternal childhood adversity and infant birth weight, gestational age, and NICU admission. 
  • Fine particulate matter air pollution and under-5 children mortality in China: A national time-stratified case-crossover study. 
  • First- or second-trimester SARS-CoV-2 infection and subsequent pregnancy outcomes. 
  • Foveal avascular zone and foveal pit formation after preterm birth. 
  • Fundamentals of Clinical Pharmacology With Application for Pregnant Women. 
  • Gestational age at initiation of 17-alpha hydroxyprogesterone caproate and recurrent preterm birth. 
  • Gestational weight gain and birth outcome in relation to prepregnancy body mass index and ethnicity. 
  • Growth During Infancy After Extremely Preterm Birth: Associations with Later Neurodevelopmental and Health Outcomes. 
  • Health and the Megacity: Urban Congestion, Air Pollution, and Birth Outcomes in Brazil. 
  • Health disparities in risk for cervical insufficiency. 
  • Hormonal contraceptive use before and after conception in relation to preterm birth and small for gestational age: an observational cohort study. 
  • Hurricane Charley Exposure and Hazard of Preterm Delivery, Florida 2004. 
  • Hydroxychloroquine PK and exposure-response in pregnancies with lupus: the importance of adherence for neonatal outcomes. 
  • Hydroxychloroquine in lupus pregnancy. 
  • Hypertension and infant outcomes: North Carolina pregnancy risks assessment monitoring system data. 
  • Impact of socioeconomic factors and health determinants on preterm birth in Brazil: a register-based study. 
  • In-Hospital Outcomes in Pregnancy After Heart Transplantation. 
  • Intrahepatic Cholestasis of Pregnancy: A Review of Diagnosis and Management. 
  • Intrapartum and Postpartum Management of Intra-amniotic Infection. 
  • Introduction. 
  • Joint Bayesian analysis of birthweight and censored gestational age using finite mixture models. 
  • Life satisfaction and preterm birth among urban black women: findings from the Baltimore preterm birth study. 
  • Lower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis? 
  • Lupus activity in pregnancy. 
  • Magnesium sulfate for neuroprotection in the setting of chorioamnionitis. 
  • Management of Preterm Premature Rupture of Membranes in the Late Preterm Period. 
  • Management of Short Cervix during Pregnancy: A Review. 
  • Maternal and Fetal Outcomes Associated With Infective Endocarditis in Pregnancy. 
  • Maternal and obstetric outcomes of listeria pregnancy: insights from a national cohort. 
  • Maternal comorbidity and adverse perinatal outcomes in survivors of adolescent and young adult cancer: A cohort study. 
  • Maternal ethnic ancestry and adverse perinatal outcomes in New York City. 
  • Maternal health prior to pregnancy and preterm birth among urban, low income black women in Baltimore: the Baltimore Preterm Birth Study. 
  • Maternal leukocytosis after antenatal corticosteroid administration: a systematic review and meta-analysis. 
  • Maternal metabolic profiling to assess fetal gestational age and predict preterm delivery: a two-centre retrospective cohort study in the US. 
  • Maternal prenatal pregnancy-related anxiety and spontaneous preterm birth in Baltimore, Maryland. 
  • Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery. 
  • Midabdominal aortic coarctation presenting with severe pre-eclampsia. 
  • Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018. 
  • Multimedia tablet or paper handout to supplement counseling during preterm birth hospitalization: a randomized controlled trial. 
  • Multiple Overimputation to Address Missing Data and Measurement Error: Application to HIV Treatment During Pregnancy and Pregnancy Outcomes. 
  • Nativity-Related Disparities in Preterm Birth and Cardiovascular Risk in a Multiracial U.S. Cohort. 
  • Necrotizing enterocolitis in infants with ductal-dependent congenital heart disease. 
  • Neighborhood deprivation and adverse birth outcomes among diverse ethnic groups. 
  • Neonatal Outcomes Associated with Noncephalic Presentation at Delivery in Preterm Birth. 
  • Obstetric outcomes in women with rheumatic disease and COVID-19 in the context of vaccination status. 
  • Open and endoscopic fetal myelomeningocele surgeries display similar in-hospital safety profiles in a large, multi-institutional database. 
  • PMTCT Option B+ Does Not Increase Preterm Birth Risk and May Prevent Extreme Prematurity: A Retrospective Cohort Study in Malawi. 
  • PROLONG Clinical Study Protocol: Hydroxyprogesterone Caproate to Reduce Recurrent Preterm Birth. 
  • Parental understanding of crucial medical jargon used in prenatal prematurity counseling. 
  • Paternal Jail Incarceration and Birth Outcomes: Evidence from New York City, 2010-2016. 
  • Pathogenesis of pregnancy complications in systemic lupus erythematosus. 
  • Patient-Reported Disease Activity and Adverse Pregnancy Outcomes in Systemic Lupus Erythematosus and Rheumatoid Arthritis. 
  • Perfluoroalkyl substances exposure in early pregnancy and preterm birth in singleton pregnancies: a prospective cohort study. 
  • Performance of a proteomic preterm delivery predictor in a large independent prospective cohort. 
  • Perinatal Considerations in Women With Previous Diagnosis of Cancer. 
  • Post-Traumatic Stress Disorder and Severe Maternal Morbidity. 
  • Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial. 
  • Predictors of adverse events among pregnant smokers exposed in a nicotine replacement therapy trial. 
  • Predictors of preterm birth in patients with mild systemic lupus erythematosus. 
  • Pregnancy Outcomes after Treatment for Cervical Cancer Precursor Lesions: An Observational Study. 
  • Pregnancy outcomes associated with viral hepatitis. 
  • Pregnancy vs. paycheck: a qualitative study of patient's experience with employment during pregnancy at high risk for preterm birth. 
  • Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor. 
  • Prenatal protease inhibitor use and risk of preterm birth among HIV-infected women initiating antiretroviral drugs during pregnancy. 
  • Preterm Birth in China Between 2015 and 2016. 
  • Preterm birth, fetal growth, and age at menarche among women exposed prenatally to diethylstilbestrol (DES). 
  • Preterm birth, long-term survival, and fertility. 
  • Preterm birth: the role of knowledge transfer and exchange. 
  • Profile of Chronic Comorbid Conditions and Obstetrical Complications Among Pregnant Women With Human Immunodeficiency Virus and Receiving Antiretroviral Therapy in the United States. 
  • Psychosocial Stress and Preterm Birth: The Impact of Parity and Race. 
  • Pulmonary Hypertension in Pregnancy: A Report of 49 Cases at Four Tertiary North American Sites. 
  • Quality measures in high-risk pregnancies: Executive Summary of a Cooperative Workshop of the Society for Maternal-Fetal Medicine, National Institute of Child Health and Human Development, and the American College of Obstetricians and Gynecologists. 
  • Racial and ethnic representation in 17-hydroxyprogesterone caproate preterm birth prevention studies: a systematic review. 
  • Rates of preterm birth in multiparous women with congenital uterine anomalies. 
  • Reasons for cesarean and medically indicated deliveries in pregnancies in women with systemic lupus erythematosus. 
  • Reducing the global burden of Preterm Birth through knowledge transfer and exchange: a research agenda for engaging effectively with policymakers. 
  • Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth. 
  • Risk factors for uteroplacental vascular compromise and inflammation. 
  • Risk of spontaneous preterm birth in relation to maternal depressive, anxiety, and stress symptoms. 
  • Risk of spontaneous preterm birth in relation to maternal exposure to intimate partner violence during pregnancy in Peru. 
  • Second trimester folate status and preterm birth. 
  • Should spontaneous and medically indicated preterm births be separated for studying aetiology? 
  • Sonographic Evaluation of the Placenta in Fontan Patients: A Case Series. 
  • Spatial-temporal modeling of the association between air pollution exposure and preterm birth: identifying critical windows of exposure. 
  • Spelling it out in black and white: Absolute measures of effect for binary outcomes: quantifying the public health impact of interventions. 
  • Temporal Events Detector for Pregnancy Care (TED-PC): A rule-based algorithm to infer gestational age and delivery date from electronic health records of pregnant women with and without COVID-19. 
  • Term complications and subsequent risk of preterm birth: registry based study. 
  • The "Hispanic paradox": an investigation of racial disparity in pregnancy outcomes at a tertiary care medical center. 
  • The Effects of Turner Syndrome, 45,X on Obstetric and Neonatal Outcomes: A Retrospective Cohort Evaluation. 
  • The Role of Congenital Cytomegalovirus Infection in Adverse Birth Outcomes: A Review of the Potential Mechanisms. 
  • The Society for Obstetric Anesthesia and Perinatology Coronavirus Disease 2019 Registry: An Analysis of Outcomes Among Pregnant Women Delivering During the Initial Severe Acute Respiratory Syndrome Coronavirus-2 Outbreak in the United States. 
  • The association between pre pregnancy body mass index and risk of preeclampsia: a registry based study from Tanzania. 
  • The associations between environmental quality and preterm birth in the United States, 2000-2005: a cross-sectional analysis. 
  • The burden of heatwave-related preterm births and associated human capital losses in China. 
  • The clinical utility of measuring complement and anti-dsDNA antibodies during pregnancy in patients with systemic lupus erythematosus. 
  • The effect of water disinfection by-products on pregnancy outcomes in two southeastern US communities. 
  • The effects of anemia on pregnancy outcome in patients with pyelonephritis. 
  • The effects of betamethasone on the amplitude integrated EEG of infants born at 34- or 35-weeks gestation. 
  • The immune checkpoint molecule, VTCN1/B7-H4, guides differentiation and suppresses proinflammatory responses and MHC class I expression in an embryonic stem cell-derived model of human trophoblast. 
  • The immunomodulatory roles of macrophages at the maternal-fetal interface. 
  • The impact of cyclophosphamide on menstruation and pregnancy in women with rheumatologic disease. 
  • The relationship of cervical microbiota diversity with race and disparities in preterm birth. 
  • The risk for recurrent preterm birth after prior preterm birth complicated by major fetal anomaly. 
  • The role of socioeconomic factors in Black-White disparities in preterm birth. 
  • Tocolysis: A Review of the Literature. 
  • Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth. 
  • Transcriptome changes affecting Hedgehog and cytokine signalling in the umbilical cord: implications for disease risk. 
  • Treatment for Mild Chronic Hypertension during Pregnancy. 
  • Trisomy 18 Pregnancies: Is there an Increased Maternal Risk? 
  • Vitamin C supplementation in pregnancy--does it decrease rates of preterm birth? A systematic review. 
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  Keywords of People

  • Cohen-Wolkowiez, Michael, Kiser-Arena Distinguished Professor, Pediatrics, Infectious Diseases
  • Dement, John McCray, Professor Emeritus in Family Medicine and Community Health, Family Medicine & Community Health,Occupational & Environmental Medicine
  • Farsiu, Sina, Professor in the Department of Biomedical Engineering, Electrical and Computer Engineering
  • Gilner, Jennifer B, Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Maternal Fetal Medicine
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering
  • Wheeler, Sarahn M, Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Maternal Fetal Medicine