Mitogen-Activated Protein Kinase 8

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  Subject Areas on Research

  • Biomedicine. Insulin resistance takes a trip through the ER. 
  • Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. 
  • Glucocorticoid treatment alleviates dystrophic myofiber pathology by activation of the calcineurin/NF-AT pathway. 
  • In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation. 
  • JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. 
  • JNK1 is required to preserve cardiac function in the early response to pressure overload. 
  • Manipulating JNK signaling with (--)-zuonin A. 
  • The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition. 
  • The role of tuberous sclerosis complex 1 in regulating innate immunity. 
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  Keywords of People

  • Zhong, Xiaoping, Professor of Pediatrics, Immunology