Cell Growth Processes
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Subject Areas on Research
- A mechanism-based antioxidant approach for the reduction of skin carcinogenesis.
- AJAP1 expression modulates glioma cell motility and correlates with tumor growth and survival.
- Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology.
- Androgen and androgen receptor antagonist responsive primary African-American benign prostate epithelial cell line.
- Annexin 1 induced by anti-inflammatory drugs binds to NF-kappaB and inhibits its activation: anticancer effects in vitro and in vivo.
- BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development.
- Breast medical oncologists' use of standard prognostic factors to predict a 21-gene recurrence score.
- Computational evaluation of methods for measuring the spatial extent of neural activation.
- Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation.
- Dasatinib (BMS-35482) has synergistic activity with paclitaxel and carboplatin in ovarian cancer cells.
- Designer monotransregulators provide a basis for a transcriptional therapy for de novo endocrine-resistant breast cancer.
- Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.
- Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model.
- Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells.
- EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase.
- Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer.
- Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4.
- Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma.
- Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma.
- Glioblastoma proto-oncogene SEC61gamma is required for tumor cell survival and response to endoplasmic reticulum stress.
- Gαz regulates BDNF-induction of axon growth in cortical neurons.
- HER2 overexpression elicits a proinflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis.
- Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein.
- Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid.
- In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer.
- Increased IL-4 production and attenuated proliferative and pro-inflammatory responses of splenocytes from wild-caught rats (Rattus norvegicus).
- KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.
- Loss of betaglycan expression in ovarian cancer: role in motility and invasion.
- Mechanical homeostasis is altered in uterine leiomyoma.
- Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment.
- MicroRNAs and their target messenger RNAs associated with ovarian cancer response to chemotherapy.
- Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer.
- Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer.
- Ral activation promotes melanomagenesis.
- Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model.
- Sporangiospore size dimorphism is linked to virulence of Mucor circinelloides.
- Stable RNA interference-mediated suppression of cyclophilin A diminishes non-small-cell lung tumor growth in vivo.
- Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress.
- Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.
- Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth.
- Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.
- The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis.
- The type III transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer.
- Therapeutic efficacy of endostatin exhibits a biphasic dose-response curve.
- Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway.
- Transforming growth factor alpha expression drives constitutive epidermal growth factor receptor pathway activation and sensitivity to gefitinib (Iressa) in human pancreatic cancer cell lines.
- Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts.
- Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia.
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Keywords of People
- Abbruzzese, James, D. C. I. Professor of Medical Oncology, Medicine, Medical Oncology
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Hilton, Matthew James, Associate Professor in Orthopaedic Surgery, Cell Biology
- Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Immunology
- Patz Jr., Edward F., James and Alice Chen Professor of Radiology, Pathology
- Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology