Dendritic Spines
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Subject Areas on Research
- A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory.
- ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory.
- Acute and Long-Term Effects of Brief Sevoflurane Anesthesia During the Early Postnatal Period in Rats.
- Adeno-associated virus-mediated ILK gene silencing in the rat NAc core.
- Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood.
- Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB.
- Astrocytes refine cortical connectivity at dendritic spines.
- Autocrine BDNF-TrkB signalling within a single dendritic spine.
- Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain.
- Calmodulin activation by calcium transients in the postsynaptic density of dendritic spines.
- Cell adhesion: separation of p120's powers?
- Changes in Neuroimmune and Neuronal Death Markers after Adolescent Alcohol Exposure in Rats are Reversed by Donepezil.
- Deafening drives cell-type-specific changes to dendritic spines in a sensorimotor nucleus important to learned vocalizations.
- Dendritic spine geometry can localize GTPase signaling in neurons.
- Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities.
- Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.
- Donepezil Reverses Dendritic Spine Morphology Adaptations and Fmr1 Epigenetic Modifications in Hippocampus of Adult Rats After Adolescent Alcohol Exposure.
- Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane.
- General anesthetic exposure in adolescent rats causes persistent maladaptations in cognitive and affective behaviors and neuroplasticity.
- Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.
- In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.
- Inhibition of the dopamine D1 receptor signaling by PSD-95.
- Localization of brain-derived neurotrophic factor to distinct terminals of mossy fiber axons implies regulation of both excitation and feedforward inhibition of CA3 pyramidal cells.
- Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall.
- Maternal Loss of Ube3a Impairs Experience-Driven Dendritic Spine Maintenance in the Developing Visual Cortex.
- MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants.
- Multiscale imaging characterization of dopamine transporter knockout mice reveals regional alterations in spine density of medium spiny neurons.
- Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation.
- Rapid Golgi analysis method for efficient and unbiased classification of dendritic spines.
- Regional-specific effects of ovarian hormone loss on synaptic plasticity in adult human APOE targeted replacement mice.
- Regulation of spine structural plasticity by Arc/Arg3.1.
- Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders.
- Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice.
- Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity.
- Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.
- Sparing of Descending Axons Rescues Interneuron Plasticity in the Lumbar Cord to Allow Adaptive Learning After Thoracic Spinal Cord Injury.
- Spine microdomains for postsynaptic signaling and plasticity.
- Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine.
- Studying signal transduction in single dendritic spines.
- Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging.
- Synaptic Actin Dysregulation, a Convergent Mechanism of Mental Disorders?
- Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance.
- The Arp2/3 Complex Is Essential for Distinct Stages of Spine Synapse Maturation, Including Synapse Unsilencing.
- The mechanisms underlying the spatial spreading of signaling activity.
- The nonkinase phorbol ester receptor alpha 1-chimerin binds the NMDA receptor NR2A subunit and regulates dendritic spine density.
- Ultrastructural abnormalities in CA1 hippocampus caused by deletion of the actin regulator WAVE-1.
- Unmasking Proteolytic Activity for Adult Visual Cortex Plasticity by the Removal of Lynx1.
- WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory.
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Keywords of People
- Soderling, Scott Haydn, George Barth Geller Distinguished Professor of Molecular Biology, Cell Biology