Green Fluorescent Proteins
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Subject Areas on Research
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A Cre-inducible fluorescent reporter for observing apical membrane dynamics.
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A Fluorescent Cell-Based System for Imaging Zika Virus Infection in Real-Time.
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A GH3-like domain in reaper is required for mitochondrial localization and induction of IAP degradation.
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A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.
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A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae.
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A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics.
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A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation.
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A broad competence to respond to SHORT ROOT revealed by tissue-specific ectopic expression.
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A circuit model for saccadic suppression in the superior colliculus.
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A cis-acting sequence homologous to the yeast filamentation and invasion response element regulates expression of a pectinase gene from the bean pathogen Colletotrichum lindemuthianum.
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A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.
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A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity.
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A functional antigenomic promoter for the paramyxovirus simian virus 5 requires proper spacing between an essential internal segment and the 3' terminus.
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A gene expression map of the Arabidopsis root.
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A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast.
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A grafted ovarian fragment rescues host fertility after chemotherapy.
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A gut-brain neural circuit for nutrient sensory transduction.
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A high-resolution root spatiotemporal map reveals dominant expression patterns.
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A lentiviral vector bearing a reverse intron demonstrates superior expression of both proteins and microRNAs.
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A method to measure myocardial calcium handling in adult Drosophila.
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A mouse model of adult-onset anaemia due to erythropoietin deficiency.
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A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
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A novel function of VCP (valosin-containing protein; p97) in the control of N-glycosylation of proteins in the endoplasmic reticulum.
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A novel gene, ROA, is required for normal morphogenesis and discharge of ascospores in Gibberella zeae.
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A novel imaging method for quantitative Golgi localization reveals differential intra-Golgi trafficking of secretory cargoes.
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A novel immunocompetent murine tumor model for the evaluation of RCAd-enhanced RDAd transduction efficacy.
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A novel intracellular protein delivery platform based on single-protein nanocapsules.
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A novel membrane-anchored Rab5 interacting protein required for homotypic endosome fusion.
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A novel rodent mammary window of orthotopic breast cancer for intravital microscopy.
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A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas.
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A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles.
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A protocol for imaging alternative splicing regulation in vivo using fluorescence reporters in transgenic mice.
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A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans.
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A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.
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A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra.
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A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans.
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A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis.
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AAV Gene Therapy for MPS1-associated Corneal Blindness.
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ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.
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Actin-associated neurabin-protein phosphatase-1 complex regulates hippocampal plasticity.
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Activation of the canonical bone morphogenetic protein (BMP) pathway during lung morphogenesis and adult lung tissue repair.
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Activation-induced endocytosis of the raft-associated transmembrane adaptor protein LAB/NTAL in B lymphocytes: evidence for a role in internalization of the B cell receptor.
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Acute in vivo genetic rescue demonstrates that phosphorylation of RIM1alpha serine 413 is not required for mossy fiber long-term potentiation.
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Adducin promotes micrometer-scale organization of beta2-spectrin in lateral membranes of bronchial epithelial cells.
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Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin.
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Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo.
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Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells.
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Agonist-specific regulation of delta-opioid receptor trafficking by G protein-coupled receptor kinase and beta-arrestin.
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Alphavirus replicon particles as candidate HIV vaccines.
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Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB.
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An auxin gradient and maximum in the Arabidopsis root apex shown by high-resolution cell-specific analysis of IAA distribution and synthesis.
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An experimental study of GFP-based FRET, with application to intrinsically unstructured proteins.
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Analysis of the biologic properties of p230 Bcr-Abl reveals unique and overlapping properties with the oncogenic p185 and p210 Bcr-Abl tyrosine kinases.
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Anchor cell invasion into the vulval epithelium in C. elegans.
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Angiogenesis-like activity of endothelial cells co-cultured with VEGF-producing smooth muscle cells.
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Angiotropism of human prostate cancer cells: implications for extravascular migratory metastasis.
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Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease.
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Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors.
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Applications for green fluorescent protein (GFP) in the study of host-pathogen interactions.
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Applications of gene fusions to green fluorescent protein and flow cytometry to the study of bacterial gene expression in host cells.
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Arabidopsis HEMERA/pTAC12 initiates photomorphogenesis by phytochromes.
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Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos.
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Assembly dynamics of FtsZ rings in Bacillus subtilis and Escherichia coli and effects of FtsZ-regulating proteins.
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Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics.
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Astrocytes follow ganglion cell axons to establish an angiogenic template during retinal development.
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Asynchronous synapse elimination in neonatal motor units: studies using GFP transgenic mice.
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Autocrine BDNF-TrkB signalling within a single dendritic spine.
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BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV.
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BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors.
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Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction.
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Barriers to productive transfection of trabecular meshwork cells.
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Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
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Binding of the beta2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recycling.
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Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells.
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Bioluminescent virion shells: new tools for quantitation of AAV vector dynamics in cells and live animals.
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Bioreactor model of neuromuscular junction with electrical stimulation for pharmacological potency testing.
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Bisphenol A affects androgen receptor function via multiple mechanisms.
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Blood-derived macrophages infiltrate the retina and activate Muller glial cells under experimental choroidal neovascularization.
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Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation.
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Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization.
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Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling.
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CD47 regulates the phagocytic clearance and replication of the Plasmodium yoelii malaria parasite.
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CDK5 regulates cell adhesion and migration in corneal epithelial cells.
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CNS inflammation and bone marrow neuropathy in type 1 diabetes.
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CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion.
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CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney.
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Ca2+/calmodulin regulates trafficking of Ca(V)1.2 Ca2+ channels in cultured hippocampal neurons.
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Calcineurin activation causes retinal ganglion cell degeneration.
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Calcium/calmodulin-dependent kinase kinase 2 regulates hematopoietic stem and progenitor cell regeneration.
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Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells.
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Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity.
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Cell type-specific expression profiling in plants via cell sorting of protoplasts from fluorescent reporter lines.
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Cell-directed assembly of lipid-silica nanostructures providing extended cell viability.
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Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes.
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Changes in gravitational force induce alterations in gene expression that can be monitored in the live, developing zebrafish heart.
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Characterization of basal pseudopod-like processes in ileal and colonic PYY cells.
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Characterization of mesonephric development and regeneration using transgenic zebrafish.
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Coiled-coil targeting of myocilin to intracellular membranes.
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Comparative assessment of fluorescent proteins for in vivo imaging in an animal model system.
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Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase.
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Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.
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Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features.
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Construction and detection of fluorescent, germline transgenic zebrafish.
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Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain.
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Cortico-cortical projections in mouse visual cortex are functionally target specific.
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Covalent protein-oligonucleotide conjugates by copper-free click reaction.
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Cryptococcus neoformans differential gene expression detected in vitro and in vivo with green fluorescent protein.
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Cryptococcus neoformans gene expression during murine macrophage infection.
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Cse1l is a negative regulator of CFTR-dependent fluid secretion.
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Cti6 is an Rpd3-Sin3 histone deacetylase-associated protein required for growth under iron-limiting conditions in Saccharomyces cerevisiae.
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Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae.
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Deafening drives cell-type-specific changes to dendritic spines in a sensorimotor nucleus important to learned vocalizations.
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Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells.
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Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases.
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Design, expression, and immunogenicity of a soluble HIV trimeric envelope fragment adopting a prefusion gp41 configuration.
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Desmoplakin: an unexpected regulator of microtubule organization in the epidermis.
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Development and use of SIV-based Integrase defective lentiviral vector for immunization.
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Development of a modified positive selection medium that allows to isolate Aspergillus oryzae strains cured of the integrated niaD-based plasmid.
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Diazo coupling method for covalent attachment of proteins to solid substrates.
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Differential effects of unfolded protein response pathways on axon injury-induced death of retinal ganglion cells.
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Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes.
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Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling protein.
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Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.
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Disproportionate relationship between APOBEC-1 expression and apolipoprotein B mRNA editing activity.
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Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities.
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Disruption of lysosome function promotes tumor growth and metastasis in Drosophila.
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Distinct Kinase-Independent Role of RIPK3 in CD11c+ Mononuclear Phagocytes in Cytokine-Induced Tissue Repair.
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Distinctive gene transduction efficiencies of commonly used viral vectors in the retina.
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Disulfide-mediated dimerization of L1 Ig domains.
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Domain 3 of hepatitis C virus core protein is sufficient for intracellular lipid accumulation.
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Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex.
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Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.
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Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants.
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Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants.
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Dynamic shuttling and intranuclear mobility of nuclear hormone receptors.
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Dynamics and elasticity of the fibronectin matrix in living cell culture visualized by fibronectin-green fluorescent protein.
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EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma.
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Early recruitment of AU-rich element-containing mRNAs determines their cytosolic fate during iron deficiency.
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Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow.
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Efficient intratracheal delivery of airway epithelial cells in mice and pigs.
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Embryonic expression and steroid regulation of brain aromatase cyp19a1b in zebrafish (Danio rerio).
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Emergent properties during dorsal closure in Drosophila morphogenesis.
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Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC.
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Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1.
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Engineering key components in a synthetic eukaryotic signal transduction pathway.
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Enhanced green fluorescent protein as a marker for localizing murine cytomegalovirus in acute and latent infection.
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Enhanced inhibition of neointimal hyperplasia by genetically engineered endothelial progenitor cells.
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Enhancement of rAAV2-mediated transgene expression in retina cells in vitro and in vivo by coadministration of low-dose chemotherapeutic drugs.
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Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus.
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Error-prone polyploid mitosis during normal Drosophila development.
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Erythropoietin activates mitochondrial biogenesis and couples red cell mass to mitochondrial mass in the heart.
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Evidence for type II cells as cells of origin of K-Ras-induced distal lung adenocarcinoma.
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Ex vivo generation of dendritic cells from cryopreserved, post-induction chemotherapy, mobilized leukapheresis from pediatric patients with medulloblastoma.
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Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.
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Expanded polyglutamine stretches form an 'aggresome'.
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Experimental validation of Monte Carlo modeling of fluorescence in tissues in the UV-visible spectrum.
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Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow.
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Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes.
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FACS-optimized mutants of the green fluorescent protein (GFP).
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FGF8 signaling is chemotactic for cardiac neural crest cells.
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FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes.
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Faithful expression of GFP from the PLCbeta2 promoter in a functional class of taste receptor cells.
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Feedback control of Swe1p degradation in the yeast morphogenesis checkpoint.
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Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus.
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Flow cytometry and bacterial pathogenesis.
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Fluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor.
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Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein.
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Fluorescence-based isolation of bacterial genes expressed within host cells.
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Focal gene induction in the liver of rats by a heat-inducible promoter using focused ultrasound hyperthermia: preliminary results.
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Forces drive basement membrane invasion in Caenorhabditis elegans.
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Framework for gradual progression of cell ontogeny in the Arabidopsis root meristem.
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Functional Transcriptomics in Diverse Intestinal Epithelial Cell Types Reveals Robust MicroRNA Sensitivity in Intestinal Stem Cells to Microbial Status.
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Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.
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GAP-43 promoter elements in transgenic zebrafish reveal a difference in signals for axon growth during CNS development and regeneration.
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GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts.
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GFP fusions to a microtubule motor protein to visualize meiotic and mitotic spindle dynamics in Drosophila.
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GFP-moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila.
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GRK5 deficiency leads to reduced hippocampal acetylcholine level via impaired presynaptic M2/M4 autoreceptor desensitization.
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Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms.
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Generation and characterization of neurogenin1-GFP transgenic medaka with potential for rapid developmental neurotoxicity screening.
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Generation of neuronal intranuclear inclusions by polyglutamine-GFP: analysis of inclusion clearance and toxicity as a function of polyglutamine length.
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Generation of recombinant adeno-associated virus vectors by a complete adenovirus-mediated approach.
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Genetic Screen Reveals Link between the Maternal Effect Sterile Gene mes-1 and Pseudomonas aeruginosa-induced Neurodegeneration in Caenorhabditis elegans.
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Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium.
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Genome-wide direct target analysis reveals a role for SHORT-ROOT in root vascular patterning through cytokinin homeostasis.
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Genome-wide significant risk associations for mucinous ovarian carcinoma.
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Gradated assembly of multiple proteins into supramolecular nanomaterials.
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Graft-extrinsic cells predominate in vein graft arterialization.
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Green fluorescent protein as a tag for molecular motor proteins.
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Green fluorescent protein marks skeletal muscle in murine cell lines and zebrafish.
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Green fluorescent protein-tagged beta-arrestin translocation as a measure of G protein-coupled receptor activation.
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Guanine analogues enhance antisense oligonucleotide-induced exon skipping in dystrophin gene in vitro and in vivo.
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Hand2 regulates extracellular matrix remodeling essential for gut-looping morphogenesis in zebrafish.
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Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus.
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Heat-induced gene expression as a novel targeted cancer gene therapy strategy.
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Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system.
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High-content profiling of cell responsiveness to graded substrates based on combinyatorially variant polymers.
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High-resolution in vivo imaging of fluorescent proteins using window chamber models.
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High-resolution, noninvasive longitudinal live imaging of immune responses.
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High-speed recording of neural spikes in awake mice and flies with a fluorescent voltage sensor.
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Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2.
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How vinculin regulates force transmission.
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Human ASPM participates in spindle organisation, spindle orientation and cytokinesis.
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Human Trial of a Genetically Modified Herpes Simplex Virus for Rapid Detection of Positive Peritoneal Cytology in the Staging of Pancreatic Cancer.
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Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2.
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Human substance P receptor lacking the C-terminal domain remains competent to desensitize and internalize.
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Hypo-osmotic stress induces calcium-dependent actin reorganization in articular chondrocytes.
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Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury.
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IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils.
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IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells.
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Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions.
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Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation.
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Identification of host-induced pathogen genes by differential fluorescence induction reporter systems.
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Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine.
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Identification of the TBX5 transactivating domain and the nuclear localization signal.
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Imaging alternative splicing in living cells.
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Imaging molecular pathways: reporter genes.
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Imaging neural activity using Thy1-GCaMP transgenic mice.
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Imaging the alternative silencing of FGFR2 exon IIIb in vivo.
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Immunofluorescent localization of a novel progesterone receptor(s) in a T47D-Y breast cancer cell line lacking genomic progesterone receptor expression.
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Improving FRET dynamic range with bright green and red fluorescent proteins.
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In Vivo Determination of Mitochondrial Function Using Luciferase-Expressing Caenorhabditis elegans: Contribution of Oxidative Phosphorylation, Glycolysis, and Fatty Acid Oxidation to Toxicant-Induced Dysfunction.
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In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation.
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In vivo US monitoring of catheter-based vascular delivery of gene microspheres in pigs: feasibility.
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In vivo gene delivery and visualization of corneal stromal cells using an adenoviral vector and keratocyte-specific promoter.
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In vivo protein expression and immune responses generated by DNA vaccines expressing mycobacterial antigens fused with a reporter protein.
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Incorporation of heterologous outer membrane and periplasmic proteins into Escherichia coli outer membrane vesicles.
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Individual beta cells within the intact islet differentially respond to glucose.
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Inhibition of Cdc42 during mitotic exit is required for cytokinesis.
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Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening.
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Inhibitory effect of b-AP15 on the 20S proteasome.
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Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models.
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Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B.
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Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.
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Intravascular location of breast cancer cells after spontaneous metastasis to the lung.
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Intravital fluorescence facilitates measurement of multiple physiologic functions and gene expression in tumors of live animals.
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JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain.
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L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.
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Lentiviral mediated gene delivery to the anterior chamber of rodent eyes.
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Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.
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Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts.
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Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer.
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Ligand-specific dynamics of the androgen receptor at its response element in living cells.
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Light-inducible gene regulation with engineered zinc finger proteins.
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Localization and function of ADP ribosylation factor A in Aspergillus nidulans.
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Localization of brain-derived neurotrophic factor to distinct terminals of mossy fiber axons implies regulation of both excitation and feedforward inhibition of CA3 pyramidal cells.
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Loss of basal cells precedes bronchiolitis obliterans-like pathological changes in a murine model of chlorine gas inhalation.
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Lung development and repair: contribution of the ciliated lineage.
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MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis.
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Maternal Loss of Ube3a Impairs Experience-Driven Dendritic Spine Maintenance in the Developing Visual Cortex.
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Maximal polar growth potential depends on the polarisome component AgSpa2 in the filamentous fungus Ashbya gossypii.
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Mechanisms regulating SHORT-ROOT intercellular movement.
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Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation.
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Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes.
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Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract.
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Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission.
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Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics.
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Mitochondrial localization of Reaper to promote inhibitors of apoptosis protein degradation conferred by GH3 domain-lipid interactions.
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Mobilization of intracellular copper stores by the ctr2 vacuolar copper transporter.
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Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth.
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Molecular and genetic approaches for the analysis of C. elegans neuronal development.
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Molecular determinants of synapsin targeting to presynaptic terminals.
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Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*.
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Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II.
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Monitoring neural activity with bioluminescence during natural behavior.
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Monosynaptic premotor circuit tracing reveals neural substrates for oro-motor coordination.
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Morphological changes among hippocampal dentate granule cells exposed to early kindling-epileptogenesis.
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Mouse germ cell clusters form by aggregation as well as clonal divisions.
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Mucosal healing and fibrosis after acute or chronic inflammation in wild type FVB-N mice and C57BL6 procollagen α1(I)-promoter-GFP reporter mice.
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Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells.
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Murine granulocyte-macrophage colony-stimulating factor expressed from a bicistronic simian immunodeficiency virus-based integrase-defective lentiviral vector does not enhance T-cell responses in mice.
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Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I.
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Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes.
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Neocortical disynaptic inhibition requires somatodendritic integration in interneurons.
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Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers.
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Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation.
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Neural cell adhesion molecule-secreting transgenic mice display abnormalities in GABAergic interneurons and alterations in behavior.
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Neuregulin-1 enhances depolarization-induced GABA release.
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Neuroligin-2 accelerates GABAergic synapse maturation in cerebellar granule cells.
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Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase family.
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Nogo receptor 1 is expressed by nearly all retinal ganglion cells.
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Non-invasive observation of repeated adenoviral GFP gene delivery to the anterior segment of the monkey eye in vivo.
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Noninvasive visualization of retinoblastoma growth and metastasis via bioluminescence imaging.
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Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
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Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure.
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Nonspecific interstitial pneumonia, alveolar proteinosis, and abnormal proprotein trafficking resulting from a spontaneous mutation in the surfactant protein C gene.
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Nonviral gene delivery from nonwoven fibrous scaffolds fabricated by interfacial complexation of polyelectrolytes.
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Novel Sfp1 transcriptional regulation of Saccharomyces cerevisiae gene expression changes during spaceflight.
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Novel integrase-defective lentiviral episomal vectors for gene transfer.
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Novel sphingosine-1-phosphate receptor modulator KRP203 combined with locally delivered regulatory T cells induces permanent acceptance of pancreatic islet allografts.
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Nrf2-mediated protection against 6-hydroxydopamine.
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Nuclear localization of NPR1 is required for activation of PR gene expression.
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Nuclear repulsion enables division autonomy in a single cytoplasm.
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O-glycosylation as a sorting determinant for cell surface delivery in yeast.
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Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation.
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Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells.
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Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium.
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Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells.
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Optimizing gene transfer to conventional outflow cells in living mouse eyes.
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Optogenetic probes.
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Out with the old, in with the new? Comparing methods for measuring protein degradation.
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PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics.
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PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors.
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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.
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Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe.
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Pericyte-like location of GFP-tagged melanoma cells: ex vivo and in vivo studies of extravascular migratory metastasis.
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Perivascular mural cells of the mouse choroid demonstrate morphological diversity that is correlated to vasoregulatory function.
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Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures.
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Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion.
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Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung.
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Polyglutamine domain proteins with expanded repeats bind neurofilament, altering the neurofilament network.
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Predicting longevity in C. elegans: fertility, mobility and gene expression.
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Prenatal and Early Postnatal Odorant Exposure Heightens Odor-Evoked Mitral Cell Responses in the Mouse Olfactory Bulb.
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Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse.
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Preventing stem cell incorporation into choroidal neovascularization by targeting homing and attachment factors.
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Primary isolate neutralization by HIV type 1-infected patient sera in the era of highly active antiretroviral therapy.
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Primary mesenchyme cell patterning during the early stages following ingression.
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Probing the domain structure of FtsZ by random truncation and insertion of GFP.
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Production of recombinant adeno-associated viral vectors and use for in vitro and in vivo administration.
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Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology.
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Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells.
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Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration.
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Protection against Mycobacterium avium by DNA vaccines expressing mycobacterial antigens as fusion proteins with green fluorescent protein.
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Protein synthesis inhibitors and the chemical chaperone TMAO reverse endoplasmic reticulum perturbation induced by overexpression of the iodide transporter pendrin.
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Quantitative enumeration of vascular smooth muscle cells and endothelial cells derived from bone marrow precursors in experimental choroidal neovascularization.
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RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues.
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RANK, RANKL, OPG, and M-CSF expression in stromal cells during corneal wound healing.
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Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells.
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RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development.
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Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules.
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Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo.
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Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching.
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Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein.
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Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics by guanine nucleotides.
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Re: initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models.
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Real-time imaging of morphogenetic movements in Drosophila using Gal4-UAS-driven expression of GFP fused to the actin-binding domain of moesin.
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Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes.
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Regeneration Genetics.
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Regeneration of amputated zebrafish fin rays from de novo osteoblasts.
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Regulated heat shock protein 27 expression in human retinal pigment epithelium.
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Regulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein.
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Regulation of the Saccharomyces cerevisiae Slt2 kinase pathway by the stress-inducible Sdp1 dual specificity phosphatase.
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Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo.
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Repressing a repressor: gibberellin-induced rapid reduction of the RGA protein in Arabidopsis.
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Retinal pigment epithelium protection from oxidant-mediated loss of MMP-2 activation requires both MMP-14 and TIMP-2.
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RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4.
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RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration.
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Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer.
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Rvs161p and sphingolipids are required for actin repolarization following salt stress.
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S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy.
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SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.
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Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria.
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Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans.
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Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses.
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Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.
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Selective modification of antigen-specific T cells by RNA electroporation.
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Signaling, desensitization, and trafficking of G protein-coupled receptors revealed by green fluorescent protein conjugates.
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Simultaneous stretching and contraction of stress fibers in vivo.
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Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis.
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Sonic hedgehog is required early in pancreatic islet development.
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Sonic hedgehog signaling pathway supports cancer cell growth during cancer radiotherapy.
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Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein.
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Sox2 expression in Schwann cells inhibits myelination in vivo and induces influx of macrophages to the nerve.
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Spatial coordination between stem cell activity and cell differentiation in the root meristem.
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Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells.
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Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide.
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Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis.
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Spindle dynamics during meiosis in Drosophila oocytes.
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Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain.
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Structural plasticity of dentate granule cell mossy fibers during the development of limbic epilepsy.
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Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans.
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Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis.
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Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles.
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Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1).
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Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts.
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Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells.
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Targeted skipping of human dystrophin exons in transgenic mouse model systemically for antisense drug development.
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Targeting inhibition of GluR1 Ser845 phosphorylation with an RNA aptamer that blocks AMPA receptor trafficking.
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Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors.
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Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins.
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Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor.
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Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion.
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The Arabidopsis RGA gene encodes a transcriptional regulator repressing the gibberellin signal transduction pathway.
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The Arabidopsis purple acid phosphatase AtPAP10 is predominantly associated with the root surface and plays an important role in plant tolerance to phosphate limitation.
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The C2 domain protein Cts1 functions in the calcineurin signaling circuit during high-temperature stress responses in Cryptococcus neoformans.
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The CD14 receptor does not mediate entry of Mycobacterium tuberculosis into human mononuclear phagocytes.
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The DELLA motif is essential for gibberellin-induced degradation of RGA.
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The L84F polymorphic variant of human O6-methylguanine-DNA methyltransferase alters stability in U87MG glioma cells but not temozolomide sensitivity.
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The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.
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The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling.
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The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.
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The candidate sour taste receptor, PKD2L1, is expressed by type III taste cells in the mouse.
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The cellular and synaptic location of activated TrkB in mouse hippocampus during limbic epileptogenesis.
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The effect of amyloidogenic peptides on bacterial aging correlates with their intrinsic aggregation propensity.
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The effect of surface agitation on ultrasound-mediated gene transfer in vitro.
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The effects of crosslinking of scaffolds engineered from cartilage ECM on the chondrogenic differentiation of MSCs.
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The exon junction complex component Magoh controls brain size by regulating neural stem cell division.
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The forces that position a mitotic spindle asymmetrically are tethered until after the time of spindle assembly.
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The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome.
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The homeodomain protein HOXB13 regulates the cellular response to androgens.
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The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding.
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The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner.
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The minus end-directed motor Kar3 is required for coupling dynamic microtubule plus ends to the cortical shmoo tip in budding yeast.
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The molecular identities of the Caenorhabditis elegans intraflagellar transport genes dyf-6, daf-10 and osm-1.
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The molecular structure of green fluorescent protein.
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The mouse forkhead gene Foxc1 is required for primordial germ cell migration and antral follicle development.
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The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo.
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The obligate intracellular pathogen Chlamydia trachomatis targets host lipid droplets.
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The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination.
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The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.
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The uses of green fluorescent protein in prokaryotes.
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Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.
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Trafficking of the vesicular acetylcholine transporter in SN56 cells: a dynamin-sensitive step and interaction with the AP-2 adaptor complex.
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Transactivation of the epidermal growth factor receptor by angiotensin II in glomerular podocytes.
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Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn.
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Transgene expression in zebrafish: A comparison of retroviral-vector and DNA-injection approaches.
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Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy.
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Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism.
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Transient opening of fibronectin type III (FNIII) domains: the interaction of the third FNIII domain of FN with anastellin.
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Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes.
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Transsynaptic Tracing from Peripheral Targets with Pseudorabies Virus Followed by Cholera Toxin and Biotinylated Dextran Amines Double Labeling.
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Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia.
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Two and three-dimensional gene transfer from enzymatically degradable hydrogel scaffolds.
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Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies.
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Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt.
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Ultra-high expression of a thermally responsive recombinant fusion protein in E. coli.
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Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons.
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Understanding the elasticity of fibronectin fibrils: unfolding strengths of FN-III and GFP domains measured by single molecule force spectroscopy.
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Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity.
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Use of Hes1-GFP reporter mice to assess activity of the Hes1 promoter in bone cells under chronic inflammation.
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VSV-G pseudotyped, MuLV-based, semi-replication-competent retrovirus for cancer treatment.
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Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells.
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Visualization and characterization of inflammatory cell recruitment and migration through the corneal stroma in endotoxin-induced keratitis.
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Visualization of dynamic trafficking of a protein kinase C betaII/green fluorescent protein conjugate reveals differences in G protein-coupled receptor activation and desensitization.
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Visualizing hidden heterogeneity in isogenic populations of C. elegans.
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Visualizing receptor endocytosis and trafficking.
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WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory.
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Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis.
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Zebrafish as a neurotoxicological model.
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Zebrafish: a see-through host and a fluorescent toolbox to probe host-pathogen interaction.
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[A novel model for visualization of tumor cell-induced angiogenesis in vivo].
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[Preparation of green fluorescent protein retrovirus and its application in mediating gene transfer into retinal pigment epithelial cells].
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[Studying pathogenesis of Alzheimer's disease in a Drosophila melanogaster model: human APP overexpression in the brain of transgenic flies leads to deficit of the synaptic protein synaptotagmin].
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[Using Hsp70 promoter to regulate target gene expression in tumor].
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beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation.
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beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi.
-
c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.
-
Keywords of People
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Bennett, Vann,
George B. Geller Distinguished Professor for Research in Molecular Biology in the School of Medicine,
Duke Cancer Institute
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Erickson, Harold Paul,
James B. Duke Distinguished Professor of Cell Biology,
Biomedical Engineering
-
Hogan, Brigid L. M.,
George Barth Geller Distinguished Professor,
Cell Biology
-
Juvvadi, Praveen Rao,
Assistant Professor in Pediatrics,
Pediatrics, Infectious Diseases
-
Liton, Paloma Borrajo,
Associate Professor in Ophthalmology,
Pathology
-
McDonnell, Donald Patrick,
Chair, Department of Pharmacology & Cancer Biology,
Duke Innovation & Entrepreneurship
-
Milano, Carmelo Alessio,
Professor of Surgery,
Surgery, Cardiovascular and Thoracic Surgery
-
Pitt, Geoffrey Stuart,
Adjunct Professor in the Department of Medicine,
Medicine, Cardiology
-
Soderling, Scott Haydn,
Professor in Cell Biology,
Cell Biology
-
Taylor, Gregory Alan,
Associate Professor in Medicine,
Immunology
-
Tsalik, Ephraim,
Associate Professor of Medicine,
Molecular Genetics and Microbiology
-
Velkey, John Matthew,
Assistant Professor of the Practice of Medical Education in the Department of Cell Biology,
Cell Biology
-
Zhong, Pei,
Professor in the Department of Mechanical Enginnering and Materials Science,
Mechanical Engineering and Materials Science