Genes, Mating Type, Fungal

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  Subject Areas on Research

  • A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans. 
  • Amt2 permease is required to induce ammonium-responsive invasive growth and mating in Cryptococcus neoformans. 
  • Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. 
  • Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha. 
  • Characterization of a mutation in yeast causing nonrandom chromosome loss during mitosis. 
  • Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana. 
  • Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. 
  • Convergent evolution of linked mating-type loci in basidiomycete fungi. 
  • Cryptococcus neoformans Mating and Genetic Crosses. 
  • Cryptococcus neoformans mates on pigeon guano: implications for the realized ecological niche and globalization. 
  • Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection. 
  • DNA sequence characterization and molecular evolution of MAT1 and MAT2 mating-type loci of the self-compatible ascomycete mold Neosartorya fischeri. 
  • Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating. 
  • Discovery of a modified tetrapolar sexual cycle in Cryptococcus amylolentus and the evolution of MAT in the Cryptococcus species complex. 
  • Divergence of protein kinase A catalytic subunits in Cryptococcus neoformans and Cryptococcus gattii illustrates evolutionary reconfiguration of a signaling cascade. 
  • E Pluribus Unum: The Fungal Kingdom as a Rosetta Stone for Biology and Medicine. 
  • Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen. 
  • Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus. 
  • Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. 
  • Evolution of fungal sexual reproduction. 
  • Evolution of the bipolar mating system of the mushroom Coprinellus disseminatus from its tetrapolar ancestors involves loss of mating-type-specific pheromone receptor function. 
  • Evolution of the mating type locus: insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii. 
  • Evolution of the sex-related locus and genomic features shared in microsporidia and fungi. 
  • Evolution under tight linkage to mating type. 
  • Function of Cryptococcus neoformans KAR7 (SEC66) in karyogamy during unisexual and opposite-sex mating. 
  • Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination. 
  • Fungal mating-type loci. 
  • G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans. 
  • Gene conversion occurs within the mating-type locus of Cryptococcus neoformans during sexual reproduction. 
  • Genetic Dissection of Sexual Reproduction in a Primary Homothallic Basidiomycete. 
  • Genetic and Genomic Analyses Reveal Boundaries between Species Closely Related to Cryptococcus Pathogens. 
  • Genetic circuits that govern bisexual and unisexual reproduction in Cryptococcus neoformans. 
  • Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties. 
  • Genetics of Cryptococcus neoformans. 
  • Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications. 
  • Genomics and Transcriptomics Analyses of the Oil-Accumulating Basidiomycete Yeast Trichosporon oleaginosus: Insights into Substrate Utilization and Alternative Evolutionary Trajectories of Fungal Mating Systems. 
  • Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct. 
  • Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis. 
  • Identification of the sex genes in an early diverged fungus. 
  • Impact of mating type, serotype, and ploidy on the virulence of Cryptococcus neoformans. 
  • Interaction between genetic background and the mating-type locus in Cryptococcus neoformans virulence potential. 
  • Isolates of Cryptococcus neoformans from infected animals reveal genetic exchange in unisexual, alpha mating type populations. 
  • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. 
  • MTL genotypes, phenotypic switching, and susceptibility profiles of Candida parapsilosis species group compared to Lodderomyces elongisporus. 
  • Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa. 
  • Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis. 
  • Mating-System Evolution: All Roads Lead to Selfing. 
  • Mating-Type-Specific Ribosomal Proteins Control Aspects of Sexual Reproduction in Cryptococcus neoformans. 
  • Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. 
  • Mechanistic plasticity of sexual reproduction and meiosis in the Candida pathogenic species complex. 
  • Microsporidia evolved from ancestral sexual fungi. 
  • Molecular and genetic evidence for a tetrapolar mating system in the basidiomycetous yeast Kwoniella mangrovensis and two novel sibling species. 
  • Morphological and genomic characterization of Filobasidiella depauperata: a homothallic sibling species of the pathogenic cryptococcus species complex. 
  • Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. 
  • Multiple Pathways to Homothallism in Closely Related Yeast Lineages in the Basidiomycota. 
  • Obligate sexual reproduction of a homothallic fungus closely related to the Cryptococcus pathogenic species complex. 
  • Orchestration of sexual reproduction and virulence by the fungal mating-type locus. 
  • Organization and evolutionary trajectory of the mating type (MAT) locus in dermatophyte and dimorphic fungal pathogens. 
  • PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex. 
  • Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans. 
  • Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans. 
  • Phylogenetic and Phylogenomic Definition of Rhizopus Species. 
  • Polyporales genomes reveal the genetic architecture underlying tetrapolar and bipolar mating systems. 
  • Ratiometric GPCR signaling enables directional sensing in yeast. 
  • Recombination hotspots flank the Cryptococcus mating-type locus: implications for the evolution of a fungal sex chromosome. 
  • Sex and virulence of human pathogenic fungi. 
  • Sex in fungi. 
  • Sex in the Mucoralean fungi. 
  • Sex-induced silencing operates during opposite-sex and unisexual reproduction in Cryptococcus neoformans. 
  • Sexual Reproduction in Dermatophytes. 
  • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. 
  • She Loves Me, She Loves Me Not: On the Dualistic Asexual/Sexual Nature of Dermatophyte Fungi. 
  • Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. 
  • Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. 
  • The Evolution of Sexual Reproduction and the Mating-Type Locus: Links to Pathogenesis of Cryptococcus Human Pathogenic Fungi. 
  • The Pheromone and Pheromone Receptor Mating-Type Locus Is Involved in Controlling Uniparental Mitochondrial Inheritance in Cryptococcus. 
  • The chromosomal region containing pab-1, mip, and the A mating type locus of the secondarily homothallic homobasidiomycete Coprinus bilanatus. 
  • The evolution of sex: a perspective from the fungal kingdom. 
  • The genetic structure and diversity of the A and B mating-type genes from the tropical oyster mushroom, Pleurotus djamor. 
  • The mating type-specific homeodomain genes SXI1 alpha and SXI2a coordinately control uniparental mitochondrial inheritance in Cryptococcus neoformans. 
  • Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans. 
  • Transitions in sexuality: recapitulation of an ancestral tri- and tetrapolar mating system in Cryptococcus neoformans. 
  • Transmission of Hypervirulence traits via sexual reproduction within and between lineages of the human fungal pathogen cryptococcus gattii. 
  • Uniparental nuclear inheritance following bisexual mating in fungi. 
  • Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. 
  • Unisexual reproduction enhances fungal competitiveness by promoting habitat exploration via hyphal growth and sporulation. 
  • Unisexual reproduction of Cryptococcus gattii. 
  • Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans. 
  • Unisexual reproduction. 
  • Unisexual versus bisexual mating in Cryptococcus neoformans: Consequences and biological impacts. 
  • Unseen sex in ancient virgin fungi. 
  • Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation. 
  • alpha AD alpha hybrids of Cryptococcus neoformans: evidence of same-sex mating in nature and hybrid fitness.