Transient Receptor Potential Channels
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Subject Areas on Research
- A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion.
- A TRPA1-dependent mechanism for the pungent sensation of weak acids.
- A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma.
- A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
- Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptors.
- Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control.
- Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons.
- Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.
- Contracture and transient receptor potential channel upregulation in the anterior glenohumeral joint capsule of patients with end-stage osteoarthritis.
- Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
- Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.
- Emerging mechanistic targets in lung injury induced by combustion-generated particles.
- Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1.
- Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon!
- How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways.
- Induction of CB1 cannabinoid receptor by inflammation in primary afferent neurons facilitates antihyperalgesic effect of peripheral CB1 agonist.
- Mechanosensitive channels in striated muscle and the cardiovascular system: not quite a stretch anymore.
- Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants.
- Menthol preference among smokers: association with TRPA1 variants.
- Molecular mechanisms of TRPV4-mediated neural signaling.
- Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1.
- Nanospring behaviour of ankyrin repeats.
- OnabotulinumtoxinA effects on trigeminal nociceptors.
- Oral thermosensing by murine trigeminal neurons: modulation by capsaicin, menthol and mustard oil.
- Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice.
- Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice.
- Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult.
- Proton-gated ion channels in mouse bone marrow stromal cells.
- Pungent products from garlic activate the sensory ion channel TRPA1.
- Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome.
- Recent Advances in Lipopolysaccharide Recognition Systems.
- Receptors, channels, and signalling in the urothelial sensory system in the bladder.
- Regulation of Pain and Itch by TRP Channels.
- Role of metabolic activation and the TRPA1 receptor in the sensory irritation response to styrene and naphthalene.
- S-nitrosylation TRiPs a calcium switch.
- Sample preparation of the human TRPA1 ion channel for cryo-EM studies.
- Sensing hot and cold with TRP channels.
- Sensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures.
- Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli.
- Sweet neurons inhibit texture discrimination by signaling TMC-expressing mechanosensitive neurons in Drosophila.
- TRP channels in disease.
- TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis.
- TRPA1 is a major oxidant sensor in murine airway sensory neurons.
- TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
- TRPA1 mediates the noxious effects of natural sesquiterpene deterrents.
- TRPA1: Acrolein meets its target.
- TRPV channels' role in osmotransduction and mechanotransduction.
- TRPV4 as osmosensor: a transgenic approach.
- Tear gas: an epidemiological and mechanistic reassessment.
- The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia.
- The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole.
- The role of TRPV4 channels in cutaneous epithelia.
- The role of Transient Receptor Potential Vanilloid 1 (TRPV1) channels in pancreatitis.
- Thermosensory and mechanosensory perception in human genetic disease.
- Transient Receptor Potential (TRP) Ion Channels in Orofacial Pain.
- Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti-inflammatory effects of eucalyptol.
- Transient receptor potential (TRP) channels and taste sensation.
- Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases.
- Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice.
- Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system?
- Trigeminal TRPs and the scent of pain.
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Keywords of People
- Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
- Jordt, Sven Eric, Associate Professor in Anesthesiology, Pharmacology & Cancer Biology