Lipid Metabolism

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  Subject Areas on Research

  • (3H)norepinephrine binding and lipolysis by isolated fat cells. 
  • (4-[18F]fluoro-3-iodobenzyl)guanidine, a potential MIBG analogue for positron emission tomography. 
  • 4-Hydroxy-2(E)-nonenal (HNE) catabolism and formation of HNE adducts are modulated by β oxidation of fatty acids in the isolated rat heart. 
  • A Fungal Arrestin Protein Contributes to Cell Cycle Progression and Pathogenesis. 
  • A LCMS-based untargeted lipidomics analysis of cleft palate in mouse. 
  • A Role for Exercise to Counter Skeletal Muscle Clock Disruption. 
  • A conversation with Robert Lefkowitz, Joseph Goldstein, and Michael Brown. Interview by Ushma S. Neil and Howard A. Rockman. 
  • A dose dependent relationship between vitamin A and brain myelin lipids in vitamin A deficient rats. 
  • A high-fat diet elicits differential responses in genes coordinating oxidative metabolism in skeletal muscle of lean and obese individuals. 
  • A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults. 
  • A mouse macrophage lipidome. 
  • A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. 
  • A simple osmium post-fixation paraffin-embedment technique to identify lipid accumulation in fish liver using medaka (Oryziaslatipes) eggs and eleutheroembryos as lipid rich models. 
  • A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration. 
  • A20 modulates lipid metabolism and energy production to promote liver regeneration. 
  • AAV9 gene replacement therapy for respiratory insufficiency in very-long chain acyl-CoA dehydrogenase deficiency. 
  • APOE2 is associated with longevity independent of Alzheimer's disease. 
  • Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. 
  • Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. 
  • Abnormalities of carbohydrate and lipid metabolism in Dahl rats. 
  • Activated α2-macroglobulin binding to human prostate cancer cells triggers insulin-like responses. 
  • Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice. 
  • Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver. 
  • Adaptive and maladaptive roles for ChREBP in the liver and pancreatic islets. 
  • Adipogenic and lipolytic effects of chronic glucocorticoid exposure. 
  • Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration. 
  • Adiponectin preserves metabolic fitness during aging. 
  • Airway epithelium as an effector of inflammation: molecular regulation of secondary mediators. 
  • Altered carbohydrate, lipid, and xenobiotic metabolism by liver from rats flown on Cosmos 1887. 
  • An interview with Sheila Collins, Ph.D. Interview by Vicki Glaser. 
  • An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells. 
  • Analysis of protein binding to receptor-doped lipid monolayers by Monte Carlo simulation. 
  • Androgens promote prostate cancer cell growth through induction of autophagy. 
  • Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease. 
  • Application of combined omics platforms to accelerate biomedical discovery in diabesity. 
  • Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study. 
  • BCAA Supplementation in Mice with Diet-induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis. 
  • Bacterial lipids: metabolism and membrane homeostasis. 
  • Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C. 
  • Bezafibrate induces autophagy and improves hepatic lipid metabolism in glycogen storage disease type Ia. 
  • Bile compositional changes and cholesterol stone formation following orthotopic liver transplantation. 
  • Biological, clinical and population relevance of 95 loci for blood lipids. 
  • Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. 
  • Blunted fat oxidation upon submaximal exercise is partially compensated by enhanced glucose metabolism in children, adolescents, and young adults with Barth syndrome. 
  • Brain Arachidonic Acid Incorporation and Turnover are not Altered in the Flinders Sensitive Line Rat Model of Human Depression. 
  • Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight. 
  • CLL cell apoptosis induced by nitric oxide synthase inhibitors: correlation with lipid solubility and NOS1 dissociation constant. 
  • Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice. 
  • Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. 
  • Case for the panel Nephrotic syndrome with fibrillary and lipid deposits. 
  • Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease. 
  • Catecholamine stimulated myocardial adenylate cyclase: effects of phospholipase digestion and the role of membrane lipids. 
  • Cell-programmed nutrient partitioning in the tumour microenvironment. 
  • Central nervous system distribution of inhaled toluene. 
  • Changes in bioactive lipids, alkylacylglycerol and ceramide, occur in HIV-infected cells. 
  • Changes in lipid profiles of liver microsomes of rats following intratracheal administration of DDT or endosulfan. 
  • Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells. 
  • Cholinergic stimulation of phosphatidylinositol hydrolysis by rat corneal epithelium in vitro. 
  • Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism. 
  • Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. 
  • Cis-acting polymorphisms affect complex traits through modifications of microRNA regulation pathways. 
  • Clinical and physiological abnormalities in hepatic function. 
  • Clusterin: an enigmatic protein recruited by diverse stimuli. 
  • Comparative genomics of Mortierella elongata and its bacterial endosymbiont Mycoavidus cysteinexigens. 
  • Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact. 
  • Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease. 
  • Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole. 
  • Cytotoxicity of intratracheally administered coal fly ash: studies on lipids in the lung of rats. 
  • Cytotoxicity of intratracheally administered coal fly ash: studies on liver and plasma lipids in rats. 
  • Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity. 
  • Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. 
  • Deep phenotyping in zebrafish reveals genetic and diet-induced adiposity changes that may inform disease risk. 
  • Deep thoughts on lipids and cognition. 
  • Deletion of CaMKK2 from the liver lowers blood glucose and improves whole-body glucose tolerance in the mouse. 
  • Dengue virus and autophagy. 
  • Dengue virus-induced autophagy regulates lipid metabolism. 
  • Development of the lipid-rich core in human atherosclerosis. 
  • Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans. 
  • Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044. 
  • Differential modulation of polyunsaturated fatty acids in patients with myocardial infarction treated with ticagrelor or clopidogrel. 
  • Diffusion tensor imaging and myelin composition analysis reveal abnormal myelination in corpus callosum of canine mucopolysaccharidosis I. 
  • Direct effects of thyroid hormones on hepatic lipid metabolism. 
  • Direct observation of poloxamer 188 insertion into lipid monolayers. 
  • Discovering novel brain lipids by liquid chromatography/tandem mass spectrometry. 
  • Discovery of Lipidome Alterations Following Traumatic Brain Injury via High-Resolution Metabolomics. 
  • Disrupted Blood-Retina Lysophosphatidylcholine Transport Impairs Photoreceptor Health But Not Visual Signal Transduction. 
  • Distinct patterns of fat metabolism in skeletal muscle of normal-weight, overweight, and obese humans. 
  • Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation. 
  • Diversity, topographic differentiation, and positional memory in human fibroblasts. 
  • Domain 3 of hepatitis C virus core protein is sufficient for intracellular lipid accumulation. 
  • Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events. 
  • Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer. 
  • Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults. 
  • Early cell-autonomous accumulation of neutral lipids during infection promotes mycobacterial growth. 
  • Early extracellular and cellular lipid deposits in aorta of cholesterol-fed rabbits. 
  • Early-life starvation alters lipid metabolism in adults to cause developmental pathology in Caenorhabditis elegans. 
  • Ectopic lipid deposition and the metabolic profile of skeletal muscle in ovariectomized mice. 
  • Effect of a community-based weight management program on weight loss and cardiovascular disease risk factors. 
  • Effect of antibiotics on the in vitro incorporation of acetate-14C into intestinal lipids. 
  • Effect of cystamine on liver lipids. 
  • Effect of dihydrostreptomycin on tissue lipids of tuberculous guinea-pigs. 
  • Effect of feeding excess of vitamin A and vitamin C on liver, plasma and adrenal lipids of rats. 
  • Effect of heparin on vitamin A induced hyperlipidemia in rats. 
  • Effect of hypervitaminosis A on intestinal lipids of rats. 
  • Effect of lysine and threonine deficient and supplement rice diets on lipids of hepatic smooth and rough endoplasmic reticulum of rats. 
  • Effect of retinol and retinoic acid on liver lipids of rats fed different levels of protein. 
  • Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients. 
  • Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice. 
  • Effects of a single bout of ultraendurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes. 
  • Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT. 
  • Effects of modulation of glycerol kinase expression on lipid and carbohydrate metabolism in human muscle cells. 
  • Effects of monosulfate esters of taurochenodeoxycholate on bile flow and biliary lipids in hamsters. 
  • Effects of temperature acclimation on Pacific bluefin tuna (Thunnus orientalis) cardiac transcriptome. 
  • Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage. 
  • Elevated lipid oxidation is associated with exceeding gestational weight gain recommendations and increased neonatal anthropometrics: a cross-sectional analysis. 
  • Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. 
  • Endogenous elevation of plasma cholecystokinin does not prevent gallstones. 
  • Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach. 
  • Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism. 
  • Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6. 
  • Epigallocatechin-3-gallate (EGCG), a green tea polyphenol, stimulates hepatic autophagy and lipid clearance. 
  • Estimating resource acquisition and at-sea body condition of a marine predator. 
  • Ether lipid metabolism by AADACL1 regulates platelet function and thrombosis. 
  • Exercise training, lipid regulation, and insulin action: a tangled web of cause and effect. 
  • Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. 
  • Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein. 
  • FGF21-FGFR1 Coordinates Phospholipid Homeostasis, Lipid Droplet Function, and ER Stress in Obesity. 
  • FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. 
  • FOXO3 growth inhibition of colonic cells is dependent on intraepithelial lipid droplet density. 
  • Factors influencing the lipid response to selective alpha 1-inhibition. 
  • Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. 
  • Fatty acid transport protein 2 reprograms neutrophils in cancer. 
  • Feeling the Burn: Intestinal Epithelial Cells Modify Their Lipid Metabolism in Response to Bacterial Fermentation Products. 
  • Fenofibrate rapidly decreases hepatic lipid and glycogen storage in neonatal mice with glycogen storage disease type Ia. 
  • Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism. 
  • From the editor: A compendium of lipidology progress. 
  • From the editor: A time of renewal for clinical lipidology. 
  • From the editor: Connectedness and lipidology. 
  • From the editor: Homeward bound? 
  • From the editor: Rounding the corner. 
  • From the editor: Weighing the advantages of lipid conference and journal. 
  • From the editor: What is the bottom line for clinical lipidology research? 
  • Fructose and sugar: A major mediator of non-alcoholic fatty liver disease. 
  • Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. 
  • Gene transcription, metabolite and lipid profiling in eco-indicator daphnia magna indicate diverse mechanisms of toxicity by legacy and emerging flame-retardants. 
  • Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. 
  • Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease. 
  • Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 
  • Genomics and Transcriptomics Analyses of the Oil-Accumulating Basidiomycete Yeast Trichosporon oleaginosus: Insights into Substrate Utilization and Alternative Evolutionary Trajectories of Fungal Mating Systems. 
  • Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin. 
  • Growth hormone and prolactin receptors in adipogenesis: STAT-5 activation, suppressors of cytokine signaling, and regulation of insulin-like growth factor I. 
  • Gut microbiome contributions to altered metabolism in a pig model of undernutrition. 
  • HDAC4 promotes Pax7-dependent satellite cell activation and muscle regeneration. 
  • Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma. 
  • Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages. 
  • Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. 
  • Hepatic failure in adult Niemann-Pick disease. 
  • Hepatic function in rats after spaceflight: effects on lipids, glycogen, and enzymes. 
  • Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance. 
  • Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. 
  • Hormone therapy: physiological complexity belies therapeutic simplicity. 
  • Host-Directed Therapies for Tuberculosis. 
  • Human aortic fibrolipid lesions. Progenitor lesions for fibrous plaques, exhibiting early formation of the cholesterol-rich core. 
  • Huntington's disease: membrane abnormalities and protein glycosylation. 
  • Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. 
  • Hyperlipidemia and transplantation: etiologic factors and therapy. 
  • Hypolipidemic activity of tetrakis-mu-(trimethylamine-boranecarboxylato)-bis(trimethylamin e- carboxyborane)-dicopper(II) in rodents and its effect on lipid metabolism. 
  • Identification and comparative analysis of hepatitis C virus-host cell protein interactions. 
  • Identification and replication of novel genetic variants of ABO gene to reduce the incidence of diseases and promote longevity by modulating lipid homeostasis. 
  • Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. 
  • Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults. 
  • Improved methodologies for the study of adipose biology: insights gained and opportunities ahead. 
  • Incorporation of palmitate-1-14C into liver lipids of rats fed millet (Sorghum vulgarie) at different protein levels. 
  • Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency. 
  • Influence of obesity-related risk factors in the aetiology of glioma. 
  • Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. 
  • Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins. 
  • Interaction of vitamin A and cortisol on liver and plasma lipids of rats. 
  • Interplay between lipids and branched-chain amino acids in development of insulin resistance. 
  • Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver. 
  • Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. 
  • Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused? 
  • Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles. 
  • Is it time to reconsider combination lipid therapy in high-risk diabetic patients? 
  • JCL roundtable: Lipid treatment targets. 
  • JCL roundtable: Pediatric lipidology. 
  • JCL roundtable: South Asian atherosclerotic risk. 
  • Kruppel-like factor 15 is required for the cardiac adaptive response to fasting. 
  • Large-scale profiling of Rab GTPase trafficking networks: the membrome. 
  • Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice. 
  • Lipid and Nucleocapsid N-Protein Accumulation in COVID-19 Patient Lung and Infected Cells. 
  • Lipid changes associated with antiretroviral therapy: results differ by reporting approach. 
  • Lipid profile of human synovial fluid following intra-articular ankle fracture. 
  • Lipid profiles of pediatric hematopoietic stem cell transplant survivors. 
  • Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. 
  • Lipid rafts in protein sorting and cell polarity in budding yeast Saccharomyces cerevisiae. 
  • Lipid requirements for leukocyte chemotaxis and phagocytosis: effects of inhibitors of phospholipid and cholesterol synthesis. 
  • Lipid-induced metabolic dysfunction in skeletal muscle. 
  • Lipid-induced mitochondrial stress and insulin action in muscle. 
  • Lipid-rich variant of a pancreatic endocrine neoplasm in an endoscopic ultrasound-guided fine needle aspiration biopsy. 
  • Lipidomics reveals a remarkable diversity of lipids in human plasma. 
  • Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation. 
  • Lipids and Their Effects in Chronic Lymphocytic Leukemia. 
  • Lipids and bariatric procedures Part 2 of 2: scientific statement from the American Society for Metabolic and Bariatric Surgery (ASMBS), the National Lipid Association (NLA), and Obesity Medicine Association (OMA). 
  • Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: EXECUTIVE SUMMARY. 
  • Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: FULL REPORT. 
  • Lipids at the interface of virus-host interactions. 
  • Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression. 
  • Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice. 
  • Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells. 
  • Loss of sirtuin 4 leads to elevated glucose- and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds. 
  • Lung, heart, kidney and spleen lipids in experimental tuberculosis in chicken. 
  • Lysolipid exchange with lipid vesicle membranes. 
  • MED1 mediator subunit is a key regulator of hepatic autophagy and lipid metabolism. 
  • Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases. 
  • Mechanical ventilation of rat lung: effect on surfactant forms. 
  • Mechanisms of activation of the RAW264.7 macrophage cell line by transfected mammalian DNA. 
  • Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases. 
  • Mechanisms of prostanoid synthesis in human synovial cells: cytokine-peptide synergism. 
  • Metabolic Dysregulation in Hepacivirus Infection of Common Marmosets (Callithrix jacchus). 
  • Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease. 
  • Metabolic activity of the lung. 
  • Metabolic coupling factors in pancreatic beta-cell signal transduction. 
  • Metabolic effects of dietary lactose in adult female rats. 
  • Metabolic effects of excess energy intake: does food composition matter? 
  • Metabolic flexibility during late pregnancy is associated with neonatal adiposity. 
  • Metabolomic Approaches Reveal the Role of CAR in Energy Metabolism. 
  • Metabolomic analysis reveals altered skeletal muscle amino acid and fatty acid handling in obese humans. 
  • Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet. 
  • Metabolomic mapping of atypical antipsychotic effects in schizophrenia. 
  • Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function. 
  • Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions. 
  • Microarray analysis of peroxisome proliferator-activated receptor-gamma induced changes in gene expression in macrophages. 
  • Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons. 
  • Microglial-neuronal interactions during neurodegenerative diseases. 
  • Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors. 
  • Mitochondria in apoptosis and human disease. 
  • Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice. 
  • Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. 
  • Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis. 
  • Monoamine oxidase A and B activities in liver of riboflavin-deficient rats. 
  • Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy. 
  • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. 
  • Multi-omic profiles of hepatic metabolism in TPN-fed preterm pigs administered new generation lipid emulsions. 
  • Multifaceted roles for lipids in viral infection. 
  • Multiparity leads to obesity and inflammation in mothers and obesity in male offspring. 
  • Muscle Krüppel-like factor 15 regulates lipid flux and systemic metabolic homeostasis. 
  • Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits. 
  • Neuromodulation, Specialized Proresolving Mediators, and Resolution of Pain. 
  • Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress. 
  • Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation. 
  • Nitrosative modifications of protein and lipid signaling molecules by reactive nitrogen species. 
  • Nonalcoholic Fatty Liver Disease and Hypercholesterolemia: Roles of Thyroid Hormones, Metabolites, and Agonists. 
  • Nonalcoholic Steatohepatitis. 
  • Novel Transcriptional Mechanisms for Regulating Metabolism by Thyroid Hormone. 
  • Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis. 
  • Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice. 
  • Obesity and lipid stress inhibit carnitine acetyltransferase activity. 
  • Obesity, cholesterol metabolism, and breast cancer pathogenesis. 
  • Old news and a new order. 
  • Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats. 
  • Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury. 
  • Oxidative damage to macromolecules in human Parkinson disease and the rotenone model. 
  • PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. 
  • PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer-associated fibroblasts. 
  • PHOSPHOLIPIDS OF THE SEXUAL SEGMENT OF THE KIDNEY OF THE INDIAN HOUSE LIZARD, HEMIDACTYLUS FLAVIVIRIDIS RUPPELL. 
  • PPAR nuclear receptors and altered RPE lipid metabolism in age-related macular degeneration. 
  • PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans. 
  • PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling. 
  • Palmitoylation increases the kinase activity of the G protein-coupled receptor kinase, GRK6. 
  • Parkin regulates neuronal lipid homeostasis through SREBP2-lipoprotein lipase pathway-implications for Parkinson's disease. 
  • Pars plana vitrectomy and internal limiting membrane peeling in an eye with foveal lipid deposition after focal laser surgery for diabetic macular edema. 
  • Pathogenesis of Nonalcoholic Steatohepatitis. 
  • Pathogenesis of Posttraumatic Osteoarthritis of the Ankle. 
  • Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia. 
  • Pathogenesis of hepatic steatosis in the parenterally fed rat. 
  • Peripapillary chorioretinal atrophy: Bruch's membrane changes and photoreceptor loss. 
  • Peripheral metabolic actions of leptin. 
  • Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252. 
  • Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats. 
  • Pharmacometabolomics of statin response. 
  • Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha. 
  • Placental transport of free palmitic and linoleic acids in the guinea pig. 
  • Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men. 
  • Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. 
  • Polarized Exosome Release from the Retinal Pigmented Epithelium. 
  • Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. 
  • Prevention of future cardiovascular disease in high-risk pediatric patients: a role for lipid lowering therapy? 
  • Protein lipidation in cell signaling. 
  • Pseudomonas invasion of type I pneumocytes is dependent on the expression and phosphorylation of caveolin-2. 
  • Quantitative ultrastructural analysis of perifibrous lipid and its association with elastin in nonatherosclerotic human aorta. 
  • Radioprotection of whole-body gamma irradiation induced alterations in lipid metabolism of liver and plasma by AET (S-2, aminoethyl isothiuronium Br. H. Br.) and serotonin in rats. 
  • Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium. 
  • Real-Time Visualization of the Precipitation and Phase Behavior of Octaethylporphyrin in Lipid Microparticles. 
  • Recycling of surfactant lipid and apoprotein-A studied by electron microscopic autoradiography. 
  • Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines. 
  • Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis. 
  • Representation of strong baseline contributions in 1H MR spectra. 
  • Results of bariatric surgery. 
  • Retinol and adrenal lipids of rats. 
  • Review article: the impact of liver-directed therapies on the atherogenic risk profile in non-alcoholic steatohepatitis. 
  • Revisiting the connection between intramyocellular lipids and insulin resistance: a long and winding road. 
  • Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. 
  • Role of inflammation in nonalcoholic steatohepatitis. 
  • Role of lymphatics in removal of sheep lung surfactant lipid. 
  • Role of receptor mechanisms in the adaptive response to habitual exercise. 
  • SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. 
  • Seasonal variations in the pattern of lipids in the sexual segment, kidney and liver of the Indian house lizard, Hemidactylus flaviviridis Ruppell. 
  • Serine Availability Influences Mitochondrial Dynamics and Function through Lipid Metabolism. 
  • Sex-specific alterations in mRNA level of key lipid metabolism enzymes in skeletal muscle of overweight and obese subjects following endurance exercise. 
  • Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. 
  • Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets. 
  • Specialized Pro-Resolving Lipid Mediators Regulate Ozone-Induced Pulmonary and Systemic Inflammation. 
  • Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation. 
  • Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics. 
  • Spleen lipids: effect of whole body gamma irradiation and radioprotective chemicals. 
  • Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics. 
  • Structural features of the terminal loop region of frog retinal rod outer segment disk membranes: I. Organization of lipid components. 
  • Structure of protein geranylgeranyltransferase-I from the human pathogen Candida albicans complexed with a lipid substrate. 
  • Studies on mode of action of vitamin A. 
  • Successful renal transplantation in a patient with congenital generalized lipodystrophy: a case report. 
  • TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation. 
  • TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. 
  • Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia. 
  • Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models. 
  • Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose. 
  • The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine. 
  • The Enigma of Glucose and Lipid Metabolism. 
  • The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide. 
  • The Sweet Path to Metabolic Demise: Fructose and Lipid Synthesis. 
  • The arterial wall and the atherosclerotic lesion. 
  • The draft genome of tropical fruit durian (Durio zibethinus). 
  • The effect of choline supplementation on hepatic steatosis in the parenterally fed rat. 
  • The homeodomain protein HOXB13 regulates the cellular response to androgens. 
  • The impact of lipid-based nutrient supplementation on anti-malarial antibodies in pregnant women in a randomized controlled trial. 
  • The lipid-rich core region of human atherosclerotic fibrous plaques. Prevalence of small lipid droplets and vesicles by electron microscopy. 
  • The outer surface lipoprotein VolA mediates utilization of exogenous lipids by Vibrio cholerae. 
  • The role of lipid-related genes, aging-related processes, and environment in healthspan. 
  • The role of lipoproteins in atherogenesis. 
  • The urinary proteome infers dysregulation of mitochondrial, lysosomal, and protein reabsorption processes in chronic kidney disease of unknown etiology (CKDu). 
  • Theoretical analysis of lipid transport in sciatic nerve. 
  • Thiazolidinediones and risk for atherosclerosis: pleiotropic effects of PPar gamma agonism. 
  • Thyroid Hormone Receptor α Regulates Autophagy, Mitochondrial Biogenesis, and Fatty Acid Use in Skeletal Muscle. 
  • Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells. 
  • Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. 
  • Thyroid hormone regulation of hepatic lipid and carbohydrate metabolism. 
  • Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. 
  • Total parenteral nutrition. 
  • Transcriptomics in the wild: Hibernation physiology in free-ranging dwarf lemurs. 
  • Transmethylation reactions are required for initial morphologic and biochemical responses of human monocytes to chemoattractants. 
  • Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice. 
  • Ultrastructure of the human aortic fibrolipid lesion. Formation of the atherosclerotic lipid-rich core. 
  • Upake of plasma lipids by extrahepatic tissues of vitamin A fed rats. 
  • Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-γ-Dependent Manner. 
  • WRP/srGAP3 facilitates the initiation of spine development by an inverse F-BAR domain, and its loss impairs long-term memory. 
  • [THE ENZYMES OF THE LEUKOCYTE]. 
  • n-3 Canola oil effectively replaces fish oil as a new safe dietary source of DHA in feed for juvenile Atlantic salmon. 
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  Keywords of People

  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Guan, Ziqiang, Research Professor in Biochemistry, Biochemistry
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Soderling, Scott Haydn, George Barth Geller Distinguished Professor of Molecular Biology, Cell Biology