TRPP Cation Channels

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  Subject Areas on Research

  • Another cystic mystery solved. 
  • Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1. 
  • Exome-Based Rare-Variant Analyses in CKD. 
  • Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the loss of polycystin-1. 
  • Interleukin-1 receptor activation aggravates autosomal dominant polycystic kidney disease by modulating regulated necrosis. 
  • Mitochondrial DNA-depleted A549 cells are resistant to bleomycin. 
  • Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1. 
  • Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity. 
  • TRP channels in disease. 
  • The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development. 
  • Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. 
  • Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene.