Radiotherapy, Intensity-Modulated

• 

  Subject Areas on Research

  • A Collimator Setting Optimization Algorithm for Dual-Arc Volumetric Modulated Arc Therapy in Pancreas Stereotactic Body Radiation Therapy. 
  • A Pooled Toxicity Analysis of Moderately Hypofractionated Proton Beam Therapy and Intensity Modulated Radiation Therapy in Early-Stage Prostate Cancer Patients. 
  • A comparison of two methodologies for radiotherapy treatment plan optimization and QA for clinical trials. 
  • A comprehensive investigation of the accuracy and reproducibility of a multitarget single isocenter VMAT radiosurgery technique. 
  • A knowledge-based approach to improving and homogenizing intensity modulated radiation therapy planning quality among treatment centers: an example application to prostate cancer planning. 
  • A method for generating intensity-modulated radiation therapy fields for small animal irradiators utilizing 3D-printed compensator molds. 
  • A methodology for selecting the beam arrangement to reduce the intensity-modulated radiation therapy (IMRT) dose to the SPECT-defined functioning lung. 
  • A methodology for using SPECT to reduce intensity-modulated radiation therapy (IMRT) dose to functioning lung. 
  • A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy. 
  • A novel convolution-based approach to address ionization chamber volume averaging effect in model-based treatment planning systems. 
  • A novel technique for VMAT QA with EPID in cine mode on a Varian TrueBeam linac. 
  • A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation. 
  • A planning quality evaluation tool for prostate adaptive IMRT based on machine learning. 
  • A prognostic volumetric threshold of gross tumor volume in head and neck cancer patients treated with radiotherapy. 
  • A quality assurance method that utilizes 3D dosimetry and facilitates clinical interpretation. 
  • A rabbit irradiation platform for outcome assessment of lung stereotactic radiosurgery. 
  • A singular value decomposition linear programming (SVDLP) optimization technique for circular cone based robotic radiotherapy. 
  • A technique of using gated-CT images to determine internal target volume (ITV) for fractionated stereotactic lung radiotherapy. 
  • A tool for patient-specific prediction of delivery discrepancies in machine parameters using trajectory log files. 
  • AAPM Task Group 198 Report: An implementation guide for TG 142 quality assurance of medical accelerators. 
  • ACR Appropriateness Criteria® ipsilateral radiation for squamous cell carcinoma of the tonsil. 
  • Adaptive replanning strategies accounting for shrinkage in head and neck IMRT. 
  • Adjuvant radiation therapy, androgen deprivation, and docetaxel for high-risk prostate cancer postprostatectomy: Results of NRG Oncology/RTOG study 0621. 
  • Advanced Treatment Technique for Locally Advanced Cervical Cancer: Time for a Standard of Care Shift? 
  • Advanced radiation therapy technologies in the treatment of rectal and anal cancer: intensity-modulated photon therapy and proton therapy. 
  • Advances in treatment techniques: arc-based and other intensity modulated therapies. 
  • American College of Radiology Appropriateness Criteria(®) treatment of stage I T1 glottic cancer. 
  • American Society of Radiation Oncology recommendations for documenting intensity-modulated radiation therapy treatments. 
  • An artificial intelligence-driven agent for real-time head-and-neck IMRT plan generation using conditional generative adversarial network (cGAN). 
  • An investigation of PRESAGE® 3D dosimetry for IMRT and VMAT radiation therapy treatment verification. 
  • An investigation of the accuracy of an IMRT dose distribution using two- and three-dimensional dosimetry techniques. 
  • Anaplastic Thyroid Carcinoma, Version 2.2015. 
  • Apparatus-dependent dosimetric differences in spine stereotactic body radiotherapy. 
  • Application of dose compensation in image-guided radiotherapy of prostate cancer. 
  • Applying pytorch toolkit to plan optimization for circular cone based robotic radiotherapy. 
  • Arc-modulated radiation therapy based on linear models. 
  • Assessment of PlanIQ Feasibility DVH for head and neck treatment planning. 
  • Association Between Choice of Radical Prostatectomy, External Beam Radiotherapy, Brachytherapy, or Active Surveillance and Patient-Reported Quality of Life Among Men With Localized Prostate Cancer. 
  • Association between bone marrow dosimetric parameters and acute hematologic toxicity in anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy. 
  • Atlas-guided prostate intensity modulated radiation therapy (IMRT) planning. 
  • Automatic IMRT planning via static field fluence prediction (AIP-SFFP): a deep learning algorithm for real-time prostate treatment planning. 
  • Benchmark Credentialing Results for NRG-BR001: The First National Cancer Institute-Sponsored Trial of Stereotactic Body Radiation Therapy for Multiple Metastases. 
  • Challenges in the clinical application of advanced technologies to reduce radiation-associated normal tissue injury. 
  • Changes in initial treatment for prostate cancer among Medicare beneficiaries, 1999-2007. 
  • Changes on Midchemoradiation Therapy Fluorodeoxyglucose Positron Emission Tomography for Cervical Cancer Are Associated with Prognosis. 
  • Chemoradiation for patients with large-volume laryngeal cancers. 
  • Chemoradiotherapy for locoregionally advanced squamous cell carcinoma of the base of tongue. 
  • Chemotherapy and intensity-modulated radiation therapy for locally advanced pancreatic cancer achieves a high rate of R0 resection. 
  • Clinical practice guidance for radiotherapy planning after induction chemotherapy in locoregionally advanced head-and-neck cancer. 
  • Commissioning and dosimetric characteristics of TrueBeam system: composite data of three TrueBeam machines. 
  • Comparison of 2D and 3D gamma analyses. 
  • Comparison of Patient- and Practitioner-Reported Toxic Effects Associated With Chemoradiotherapy for Head and Neck Cancer. 
  • Comparison of three concomitant boost techniques for early-stage breast cancer. 
  • Comparisons of volumetric modulated arc therapy (VMAT) quality assurance (QA) systems: sensitivity analysis to machine errors. 
  • Concurrent chemotherapy and intensity-modulated radiation therapy for anal canal cancer patients: a multicenter experience. 
  • Concurrent chemotherapy and intensity-modulated radiotherapy for organ preservation of locoregionally advanced oral cavity cancer. 
  • Daily bone alignment with limited repeat CT correction rivals daily ultrasound alignment for prostate radiotherapy. 
  • Delivered Dose Distribution Visualized Directly With Onboard kV-CBCT: Proof of Principle. 
  • Development of a 3D remote dosimetry protocol compatible with MRgIMRT. 
  • Development of an accurate EPID-based output measurement and dosimetric verification tool for electron beam therapy. 
  • Diode-based transmission detector for IMRT delivery monitoring: a validation study. 
  • Diode-based transmission detector for IMRT delivery monitoring: a validation study. 
  • Dose as a function of lung volume and planned treatment volume in helical tomotherapy intensity-modulated radiation therapy-based stereotactic body radiation therapy for small lung tumors. 
  • Dose prediction via distance-guided deep learning: Initial development for nasopharyngeal carcinoma radiotherapy. 
  • Dose-volume toxicity modeling for de-intensified chemo-radiation therapy for HPV-positive oropharynx cancer. 
  • Dosimetric Predictors of Patient-Reported Xerostomia and Dysphagia With Deintensified Chemoradiation Therapy for HPV-Associated Oropharyngeal Squamous Cell Carcinoma. 
  • Dosimetric analysis of the alopecia preventing effect of hippocampus sparing whole brain radiation therapy. 
  • Dosimetric assessment of rigid setup error by CBCT for HN-IMRT. 
  • Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI). 
  • Dosimetric comparison of 6 MV and 15 MV single arc rapidarc to helical TomoTherapy for the treatment of pancreatic cancer. 
  • Dosimetric comparison of four target alignment methods for prostate cancer radiotherapy. 
  • Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT. 
  • Dosimetric effect of intrafraction motion and residual setup error for hypofractionated prostate intensity-modulated radiotherapy with online cone beam computed tomography image guidance. 
  • Dosimetry tools and techniques for IMRT. 
  • Effect of increasing experience on dosimetric and clinical outcomes in the management of malignant pleural mesothelioma with intensity-modulated radiation therapy. 
  • Effect of machine learning methods on predicting NSCLC overall survival time based on Radiomics analysis. 
  • Efficient independent planar dose calculation for FFF IMRT QA with a bivariate Gaussian source model. 
  • Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas. 
  • Emerging role of intensity-modulated radiation therapy in anorectal cancer. 
  • Establishing the feasibility of the dosimetric compliance criteria of RTOG 1308: phase III randomized trial comparing overall survival after photon versus proton radiochemotherapy for inoperable stage II-IIIB NSCLC. 
  • Evaluation of a commercial DIR platform for contour propagation in prostate cancer patients treated with IMRT/VMAT. 
  • Evaluation of dosimetric uncertainty caused by MR geometric distortion in MRI-based liver SBRT treatment planning. 
  • Evaluation of integrated respiratory gating systems on a Novalis Tx system. 
  • Evolution and Management of Treatment-Related Toxicity in Anal Cancer. 
  • Extension of the NCAT phantom for the investigation of intra-fraction respiratory motion in IMRT using 4D Monte Carlo. 
  • FDG-PET assessment of the effect of head and neck radiotherapy on parotid gland glucose metabolism. 
  • Fast, high-resolution 3D dosimetry utilizing a novel optical-CT scanner incorporating tertiary telecentric collimation. 
  • Fitting NTCP models to bladder doses and acute urinary symptoms during post-prostatectomy radiotherapy. 
  • Functional and molecular image guidance in radiotherapy treatment planning optimization. 
  • HPV16-associated squamous cell carcinoma of the tongue metastatic to the ciliary body, iris, and lacrimal gland. 
  • Helical IMRT-Based Stereotactic Body Radiation Therapy Using an Abdominal Compression Technique and Modified Fractionation Regimen for Small Hepatocellular Carcinoma. 
  • Helical tomotherapy for bilateral breast cancer: Clinical experience. 
  • Helical tomotherapy planning for lung cancer based on ventilation magnetic resonance imaging. 
  • Image Guided Hypofractionated Postprostatectomy Intensity Modulated Radiation Therapy for Prostate Cancer. 
  • Image acquisition optimization of a limited-angle intrafraction verification (LIVE) system for lung radiotherapy. 
  • Impact of Esophageal Motion on Dosimetry and Toxicity With Thoracic Radiation Therapy. 
  • Impact of dose calculation accuracy during optimization on lung IMRT plan quality. 
  • Impact of volumetric modulated arc therapy technique on treatment with partial breast irradiation. 
  • Improving Quality and Consistency in NRG Oncology Radiation Therapy Oncology Group 0631 for Spine Radiosurgery via Knowledge-Based Planning. 
  • In Reply to Fiorino and Cozzarini. 
  • Incorporating Case-Based Reasoning for Radiation Therapy Knowledge Modeling: A Pelvic Case Study. 
  • Incorporating single-side sparing in models for predicting parotid dose sparing in head and neck IMRT. 
  • Independent calculation of monitor units for VMAT and SPORT. 
  • Independent verification of gantry angle for pre-treatment VMAT QA using EPID. 
  • Induction chemotherapy with carboplatin, nab-paclitaxel and cetuximab for at least N2b nodal status or surgically unresectable squamous cell carcinoma of the head and neck. 
  • Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management. 
  • Initial analysis of the dosimetric benefit and clinical resource cost of CBCT-based online adaptive radiotherapy for patients with cancers of the cervix or rectum. 
  • Input feature design and its impact on the performance of deep learning models for predicting fluence maps in intensity-modulated radiation therapy. 
  • Insights of an AI agent via analysis of prediction errors: a case study of fluence map prediction for radiation therapy planning. 
  • Integral dose conservation in radiotherapy. 
  • Intensity modulated radiation therapy reduces gastrointestinal toxicity in locally advanced pancreas cancer. 
  • Intensity-Modulated Radiation Therapy Is Not Associated with Perioperative or Survival Benefit over 3D-Conformal Radiotherapy for Rectal Cancer. 
  • Intensity-modulated radiation therapy for anal cancer. 
  • Intensity-modulated radiation therapy for anal cancer: toxicity versus outcomes. 
  • Intensity-modulated radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis. 
  • Intensity-modulated radiation therapy for gastrointestinal tumors. 
  • Intensity-modulated radiation therapy, proton therapy, or conformal radiation therapy and morbidity and disease control in localized prostate cancer. 
  • Introducing matrix sparsity with kernel truncation into dose calculations for fluence optimization. 
  • Investigation of the feasibility of relative 3D dosimetry in the Radiologic Physics Center Head and Neck IMRT phantom using presage/optical-CT. 
  • Is a 3-mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer? 
  • Is a single isocenter sufficient for volumetric modulated arc therapy radiosurgery when multiple itracranial metastases are spatially dispersed? 
  • Knowledge-Based Statistical Inference Method for Plan Quality Quantification. 
  • Knowledge-Based Tradeoff Hyperplanes for Head and Neck Treatment Planning. 
  • Knowledge-based adaptive planning quality assurance using dosimetric indicators for stereotactic adaptive radiotherapy for pancreatic cancer. 
  • Knowledge-based planning for intensity-modulated radiation therapy: A review of data-driven approaches. 
  • LINAC based stereotactic radiosurgery for multiple brain metastases: guidance for clinical implementation. 
  • Lung IMRT planning with automatic determination of beam angle configurations. 
  • MRI-based treatment planning for liver stereotactic body radiotherapy: validation of a deep learning-based synthetic CT generation method. 
  • Methods, safety, and early clinical outcomes of dose escalation using simultaneous integrated and sequential boosts in patients with locally advanced gynecologic malignancies. 
  • Modeling of multiple planning target volumes for head and neck treatments in knowledge-based treatment planning. 
  • Modeling the dosimetry of organ-at-risk in head and neck IMRT planning: an intertechnique and interinstitutional study. 
  • Monte Carlo calculation of imaging doses from diagnostic multidetector CT and kilovoltage cone-beam CT as part of prostate cancer treatment plans. 
  • Monte Carlo-based dosimetry of head-and-neck patients treated with SIB-IMRT. 
  • Moving from IMRT QA measurements toward independent computer calculations using control charts. 
  • Multi-omics to predict acute radiation esophagitis in patients with lung cancer treated with intensity-modulated radiation therapy. 
  • National survey of patient specific IMRT quality assurance in China. 
  • Novel Technologies for Improved Treatment Outcome and Patient Safety in Cancer Radiotherapy. 
  • On the feasibility of optical-CT imaging in media of different refractive index. 
  • On the sensitivity of TG-119 and IROC credentialing to TPS commissioning errors. 
  • On the use of trajectory log files for machine & patient specific QA. 
  • On-board patient positioning for head-and-neck IMRT: comparing digital tomosynthesis to kilovoltage radiography and cone-beam computed tomography. 
  • Optimizing patient positioning for intensity modulated radiation therapy in hippocampal-sparing whole brain radiation therapy. 
  • PET/CT of cancer patients: part 2, deformable registration imaging before and after chemotherapy for radiation treatment planning in head and neck cancer. 
  • Parameter optimization in HN-IMRT for Elekta linacs. 
  • Parotid gland dose in intensity-modulated radiotherapy for head and neck cancer: is what you plan what you get? 
  • Pathologic complete response of a malignant peripheral nerve sheath tumor in the lung treated with neoadjuvant Ifosfamide and radiation therapy. 
  • Pattern of failure in anaplastic glioma patients with an IDH1/2 mutation. 
  • Phase 1 Dose Escalation Study of Accelerated Radiation Therapy With Concurrent Chemotherapy for Locally Advanced Lung Cancer. 
  • Pixel response-based EPID dosimetry for patient specific QA. 
  • Point/Counterpoint. A 3D-conformal technique is better than IMRT or VMAT for lung SBRT. 
  • Postoperative Radiation Therapy for Prostate Cancer: Comparison of Conventional Versus Hypofractionated Radiation Regimens. 
  • Preliminary outcome and toxicity report of extended-field, intensity-modulated radiation therapy for gynecologic malignancies. 
  • Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers. 
  • Prospective Phase 2 Study of Radiation Therapy Dose and Volume De-escalation for Elective Neck Treatment of Oropharyngeal and Laryngeal Cancer. 
  • Prostate cancer and the hypofractionation hypothesis. 
  • Prostate cancer-specific mortality after radical prostatectomy or external beam radiation therapy in men with 1 or more high-risk factors. 
  • Prostate intrafraction motion evaluation using kV fluoroscopy during treatment delivery: a feasibility and accuracy study. 
  • Proton Whole-Lung Irradiation: Initial Report of Outcomes. 
  • Proton therapy for the treatment of inflammatory breast cancer. 
  • Proton-beam therapy after radical prostatectomy: Continued DVH idolatry? 
  • Quality assurance for online adapted treatment plans: benchmarking and delivery monitoring simulation. 
  • Quality of Life in Patients With Low-Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy: A Phase 3 Randomized Clinical Trial. 
  • Quantifying the dosimetric trade-offs when using intensity-modulated radiotherapy to treat concave targets containing normal tissues. 
  • Quantitative Approach to Failure Mode and Effect Analysis for Linear Accelerator Quality Assurance. 
  • Quantitative analysis of the factors which affect the interpatient organ-at-risk dose sparing variation in IMRT plans. 
  • Quantitative comparison of automatic and manual IMRT optimization for prostate cancer: the benefits of DVH prediction. 
  • RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. 
  • Radiation treatment planning and delivery strategies for a pregnant brain tumor patient. 
  • Radiosurgery treatment planning using conformal arc informed volumetric modulated arc therapy. 
  • Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes. 
  • Re-examining TG-142 recommendations in light of modern techniques for linear accelerator based radiosurgery. 
  • Real-time pretreatment review limits unacceptable deviations on a cooperative group radiation therapy technique trial: quality assurance results of RTOG 0933. 
  • Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002). 
  • Reflecting on survivorship outcomes to aid initial decision making in patients treated for IDH-mutated anaplastic glioma. 
  • Reirradiation for recurrent head and neck cancer. 
  • Retrospective quality metrics review of stereotactic radiosurgery plans treating multiple targets using single-isocenter volumetric modulated arc therapy. 
  • Risk of Pelvic Fracture With Radiation Therapy in Older Patients. 
  • Seduced by technology? 
  • Semiautomated head-and-neck IMRT planning using dose warping and scaling to robustly adapt plans in a knowledge database containing potentially suboptimal plans. 
  • Similarities between static and rotational intensity-modulated plans. 
  • Simultaneous integrated boost (SIB) for treatment of gynecologic carcinoma: Intensity-modulated radiation therapy (IMRT) vs volumetric-modulated arc therapy (VMAT) radiotherapy. 
  • Single institution's dosimetry and IGRT analysis of prostate SBRT. 
  • Single isocenter SRS using CAVMAT offers improved robustness to commissioning and treatment delivery uncertainty compared to VMAT. 
  • Standardized beam bouquets for lung IMRT planning. 
  • Stereotactic radiotherapy for malignancies involving the trigeminal and facial nerves. 
  • Strategies for optimizing the response of cancer and normal tissues to radiation. 
  • Study of Spinal Cord Substructure Expansion Margin in Esophageal Cancer. 
  • Superior prognostic utility of gross and metabolic tumor volume compared to standardized uptake value using PET/CT in head and neck squamous cell carcinoma patients treated with intensity-modulated radiotherapy. 
  • Survival Outcomes of Elderly Patients With Glioblastoma Multiforme in Their 75th Year or Older Treated With Adjuvant Therapy. 
  • Technical note: Determining the applicability of a clinical knowledge-based learning model via prospective outlier detection. 
  • Technical note: Interpolated Pareto surface similarity metrics for multi-criteria optimization in radiation therapy. 
  • Technology assessment: vigilance required. 
  • Temporal lobe injury patterns following intensity modulated radiotherapy in a large cohort of nasopharyngeal carcinoma patients. 
  • The ASTRO clinical practice guidelines in cervical cancer: Optimizing radiation therapy for improved outcomes. 
  • The Effect of Various Dose Normalization Strategies When Implementing Linear Boltzmann Transport Equation Dose Calculation for Lung Stereotactic Body Radiation Therapy Planning. 
  • The Role of Radiotherapy for Chordoma Patients Managed With Surgery: Analysis of the National Cancer Database. 
  • The Use of Re-irradiation in Locally Recurrent, Non-metastatic Rectal Cancer. 
  • The VAMPIRE challenge: A multi-institutional validation study of CT ventilation imaging. 
  • The application of distance transformation on parameter optimization of inverse planning in intensity-modulated radiation therapy. 
  • The management of imaging dose during image-guided radiotherapy: report of the AAPM Task Group 75. 
  • The markerless lung target tracking AAPM Grand Challenge (MATCH) results. 
  • The role of external beam radiotherapy in the treatment of hepatocellular cancer. 
  • The role of seminal vesicle motion in target margin assessment for online image-guided radiotherapy for prostate cancer. 
  • The role of whole brain radiation therapy in the management of melanoma brain metastases. 
  • Three IMRT advanced planning tools: A multi-institutional side-by-side comparison. 
  • To Fracture Not-Sustained Benefits of Intensity Modulated Radiation Therapy (IMRT) in Pelvic Malignancies. 
  • Transfer learning for fluence map prediction in adrenal stereotactic body radiation therapy. 
  • Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats. 
  • Using FDG-PET to measure early treatment response in head and neck squamous cell carcinoma: quantifying intrinsic variability in order to understand treatment-induced change. 
  • Utilizing knowledge from prior plans in the evaluation of quality assurance. 
  • Virtual patient-specific QA with DVH-based metrics. 
  • Volumetric arc intensity-modulated therapy for spine body radiotherapy: comparison with static intensity-modulated treatment. 
  • Volumetric-modulated arc therapy: effective and efficient end-to-end patient-specific quality assurance. 
• 

  Keywords of People

  • O'Daniel, Jennifer Colleen, Assistant Professor of Radiation Oncology, Radiation Oncology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Wu, Qingrong, Professor of Radiation Oncology, Radiation Oncology
  • Yoo, Sua, Associate Professor of Radiation Oncology, Radiation Oncology