E2F3 Transcription Factor
Subject Areas on Research
- A role for E2F activities in determining the fate of Myc-induced lymphomagenesis.
- Distinctions in the specificity of E2F function revealed by gene expression signatures.
- E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
- Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma.
- Gene expression phenotypic models that predict the activity of oncogenic pathways.
- Myc requires distinct E2F activities to induce S phase and apoptosis.
- Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
- The E2F1-3 transcription factors are essential for cellular proliferation.
- Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice.